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MX2024012982A - Metodos para la generacion de celulas-t a partir de celulas madre y metodos inmunoterapeuticos que utilizan las celulas-t - Google Patents

Metodos para la generacion de celulas-t a partir de celulas madre y metodos inmunoterapeuticos que utilizan las celulas-t

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Publication number
MX2024012982A
MX2024012982A MX2024012982A MX2024012982A MX2024012982A MX 2024012982 A MX2024012982 A MX 2024012982A MX 2024012982 A MX2024012982 A MX 2024012982A MX 2024012982 A MX2024012982 A MX 2024012982A MX 2024012982 A MX2024012982 A MX 2024012982A
Authority
MX
Mexico
Prior art keywords
cells
methods
generating
immunotherapeutic
stem
Prior art date
Application number
MX2024012982A
Other languages
English (en)
Inventor
Gay M Crooks
Amelie Montel-Hagen
Christopher S Seet
Original Assignee
The Regents Of The Universtiy Of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Regents Of The Universtiy Of California filed Critical The Regents Of The Universtiy Of California
Publication of MX2024012982A publication Critical patent/MX2024012982A/es

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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
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    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/00—Cellular immunotherapy
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    • A61K40/32—T-cell receptors [TCR]
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
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Abstract

Se proporcionan métodos y composición para la producción de células T; también se proporcionan métodos terapéuticos usando las células T diseñadas; por ejemplo, en ciertos aspectos los métodos incluyen preparar composiciones de cultivos celulares tridimensionales que comprenden células estromales y células madre o progenitoras hematopoyéticas en un medio libre de suero para producir células T.
MX2024012982A 2015-10-30 2018-04-26 Metodos para la generacion de celulas-t a partir de celulas madre y metodos inmunoterapeuticos que utilizan las celulas-t MX2024012982A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562248931P 2015-10-30 2015-10-30
US201562265204P 2015-12-09 2015-12-09
US201662359456P 2016-07-07 2016-07-07
PCT/US2016/059375 WO2017075389A1 (en) 2015-10-30 2016-10-28 Methods of generating t-cells from stem cells and immunotherapeutic methods using the t-cells

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MX2024012982A true MX2024012982A (es) 2024-11-08

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MX2018005274A MX2018005274A (es) 2015-10-30 2016-10-28 Metodos para la generacion de celulas-t a partir de celulas madre y metodos inmunoterapeuticos que utilizan las celulas-t.
MX2024012982A MX2024012982A (es) 2015-10-30 2018-04-26 Metodos para la generacion de celulas-t a partir de celulas madre y metodos inmunoterapeuticos que utilizan las celulas-t

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