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GB202312988D0 - Thymic organoids - Google Patents

Thymic organoids

Info

Publication number
GB202312988D0
GB202312988D0 GBGB2312988.5A GB202312988A GB202312988D0 GB 202312988 D0 GB202312988 D0 GB 202312988D0 GB 202312988 A GB202312988 A GB 202312988A GB 202312988 D0 GB202312988 D0 GB 202312988D0
Authority
GB
United Kingdom
Prior art keywords
thymic organoids
organoids
thymic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB2312988.5A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Francis Crick Institute Ltd
Original Assignee
Francis Crick Institute Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Francis Crick Institute Ltd filed Critical Francis Crick Institute Ltd
Priority to GBGB2312988.5A priority Critical patent/GB202312988D0/en
Publication of GB202312988D0 publication Critical patent/GB202312988D0/en
Priority to PCT/EP2024/073738 priority patent/WO2025045783A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/065—Thymocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
    • C12N2502/1185—Thymus cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2513/00—3D culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C12N2533/74—Alginate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
GBGB2312988.5A 2023-08-25 2023-08-25 Thymic organoids Ceased GB202312988D0 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GBGB2312988.5A GB202312988D0 (en) 2023-08-25 2023-08-25 Thymic organoids
PCT/EP2024/073738 WO2025045783A1 (en) 2023-08-25 2024-08-23 Thymic organoids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB2312988.5A GB202312988D0 (en) 2023-08-25 2023-08-25 Thymic organoids

Publications (1)

Publication Number Publication Date
GB202312988D0 true GB202312988D0 (en) 2023-10-11

Family

ID=88237129

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB2312988.5A Ceased GB202312988D0 (en) 2023-08-25 2023-08-25 Thymic organoids

Country Status (2)

Country Link
GB (1) GB202312988D0 (en)
WO (1) WO2025045783A1 (en)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2016343682A1 (en) * 2015-10-30 2018-06-14 The Regents Of The University Of California Methods of generating T-cells from stem cells and immunotherapeutic methods using the T-cells
KR101721514B1 (en) * 2016-08-02 2017-03-30 부산대학교 산학협력단 Cell scaffold for three dimensional cell culture comprising agarose, decelluarized extracellular matrix and collagen
US20230002727A1 (en) * 2019-11-25 2023-01-05 Allegheny Singer Research Institute Thymus organoids bioengineered from human pluripotent stem cells
GB2601793B (en) * 2020-12-10 2025-07-23 The Francis Crick Institute Ltd Thymic constructs and uses thereof
EP4347793A1 (en) * 2021-05-25 2024-04-10 Universiteit Gent Generating t cell precursors via agonizing tumor necrosis factor receptor 2
CN115287262B (en) * 2022-01-28 2024-04-02 浙江中医药大学 Thymic organoid microspheres and preparation methods and applications thereof

Also Published As

Publication number Publication date
WO2025045783A1 (en) 2025-03-06

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)