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MX2022010831A - Formulaciones inyectables de liberacion extendida que comprenden un agente activo de isoxazolina, metodos y usos de las mismas. - Google Patents

Formulaciones inyectables de liberacion extendida que comprenden un agente activo de isoxazolina, metodos y usos de las mismas.

Info

Publication number
MX2022010831A
MX2022010831A MX2022010831A MX2022010831A MX2022010831A MX 2022010831 A MX2022010831 A MX 2022010831A MX 2022010831 A MX2022010831 A MX 2022010831A MX 2022010831 A MX2022010831 A MX 2022010831A MX 2022010831 A MX2022010831 A MX 2022010831A
Authority
MX
Mexico
Prior art keywords
extended release
injectable formulations
active agent
release injectable
methods
Prior art date
Application number
MX2022010831A
Other languages
English (en)
Inventor
Susan Mancini Cady
Peter Cheifetz
Izabela Galeska
Fallois Loic Le Hir De
Original Assignee
Boehringer Ingelheim Animal Health Usa Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Animal Health Usa Inc filed Critical Boehringer Ingelheim Animal Health Usa Inc
Publication of MX2022010831A publication Critical patent/MX2022010831A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Formulaciones inyectables de liberación extendida para combatir parásitos en animales, que comprenden al menos un agente activo de isoxazolina, un polímero farmacéuticamente aceptable y un solvente. Esta invención también provee métodos mejorados para erradicar, controlar y prevenir infecciones e infestaciones por parásitos en un animal que comprende administrar las formulaciones inyectables de liberación extendida de la invención a un animal que lo necesita.
MX2022010831A 2015-04-08 2017-10-05 Formulaciones inyectables de liberacion extendida que comprenden un agente activo de isoxazolina, metodos y usos de las mismas. MX2022010831A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562144871P 2015-04-08 2015-04-08

Publications (1)

Publication Number Publication Date
MX2022010831A true MX2022010831A (es) 2022-09-29

Family

ID=57072717

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2017012848A MX2017012848A (es) 2015-04-08 2016-04-06 Formulaciones inyectables de liberacion extendida que comprenden un agente activo de isoxazolina, metodos y usos de las mismas.
MX2022010831A MX2022010831A (es) 2015-04-08 2017-10-05 Formulaciones inyectables de liberacion extendida que comprenden un agente activo de isoxazolina, metodos y usos de las mismas.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2017012848A MX2017012848A (es) 2015-04-08 2016-04-06 Formulaciones inyectables de liberacion extendida que comprenden un agente activo de isoxazolina, metodos y usos de las mismas.

Country Status (17)

Country Link
US (2) US20170020848A1 (es)
EP (1) EP3280413A1 (es)
JP (2) JP6824900B2 (es)
KR (1) KR102593069B1 (es)
CN (1) CN108055825B (es)
AR (1) AR104212A1 (es)
AU (3) AU2016246598B2 (es)
BR (1) BR112017021073A2 (es)
CA (1) CA2981797C (es)
CL (1) CL2017002536A1 (es)
CO (1) CO2017010065A2 (es)
EA (2) EA036272B1 (es)
IL (1) IL254813B (es)
MX (2) MX2017012848A (es)
SG (2) SG10201912724SA (es)
UY (1) UY36610A (es)
WO (1) WO2016164487A1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY37137A (es) * 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
CA3059114A1 (en) * 2017-04-05 2018-10-11 Boehringer Ingelheim Animal Health USA Inc. Crystalline forms of (s)-afoxolaner
ES2971223T3 (es) 2017-04-13 2024-06-04 Ceva Sante Animale Implante para tratar infestaciones por parasitos
UA127892C2 (uk) 2017-11-07 2024-02-07 Інтервет Інтернешнл Б.В. Спосіб одержання частинок ізоксазоліну великого розміру
PH12020550555B1 (en) 2017-11-07 2024-03-06 Intervet Int Bv Injectable isoxazoline pharmaceutical compositions and uses thereof
AU2018385363B2 (en) * 2017-12-12 2024-06-13 Intervet International B.V. Implantable isoxazoline pharmaceutical compositions and uses thereof
TWI812673B (zh) 2018-02-12 2023-08-21 美商富曼西公司 用於防治無脊椎害蟲之萘異噁唑啉化合物
AR116524A1 (es) * 2018-10-04 2021-05-19 Elanco Tiergesundheit Ag Potenciación de tratamiento de helmintos
WO2020180635A1 (en) * 2019-03-01 2020-09-10 Boehringer Ingelheim Animal Health USA Inc. Injectable clorsulon compositions, methods and uses thereof
PH12021552713A1 (en) * 2019-05-03 2022-07-04 Intervet Int Bv Injectable pharmaceutical compositions and uses thereof
US12497370B2 (en) 2019-12-18 2025-12-16 Elanco Tiergesundheit Ag Isoxazoline derivatives
DK4153133T3 (da) * 2020-05-20 2024-02-05 Intervet Int Bv Injicerbare farmaceutiske sammensætninger og anvendelser deraf
AU2021311722A1 (en) 2020-07-24 2023-02-02 Elanco Us Inc. Process for making an isoxazoline compound and intermediate thereof
WO2022140728A1 (en) * 2020-12-21 2022-06-30 Boehringer Ingelheim Animam Health Usa Inc. Parasiticidal collar comprising isoxazoline compounds
AU2022306297A1 (en) 2021-07-09 2024-02-08 Plexium, Inc. Aryl compounds and pharmaceutical compositions that modulate ikzf2
CN118477040B (zh) * 2024-04-11 2025-02-25 河北威远药业有限公司 一种氟雷拉纳溶液的制备方法
WO2025257633A1 (en) 2024-06-12 2025-12-18 Boehringer Ingelheim Vetmedica Gmbh Long-acting castor oil-containing injectable formulations and methods of use thereof
WO2026024600A1 (en) * 2024-07-22 2026-01-29 Zoetis Services Llc Isoxazoline and macrocyclic lactone microspheres

Family Cites Families (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3740421A (en) 1966-09-19 1973-06-19 Basf Wyandotte Corp Polyoxyethylene-polyoxypropylene aqueous gels
US3950360A (en) 1972-06-08 1976-04-13 Sankyo Company Limited Antibiotic substances
JPS4914624A (es) 1972-06-08 1974-02-08
SE434277B (sv) 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4134973A (en) 1977-04-11 1979-01-16 Merck & Co., Inc. Carbohydrate derivatives of milbemycin and processes therefor
US4199569A (en) 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof
US4144352A (en) 1977-12-19 1979-03-13 Merck & Co., Inc. Milbemycin compounds as anthelmintic agents
US4203976A (en) 1978-08-02 1980-05-20 Merck & Co., Inc. Sugar derivatives of C-076 compounds
JPS57139012A (en) 1981-02-23 1982-08-27 Sankyo Co Ltd Anthelmintic composition
US4427663A (en) 1982-03-16 1984-01-24 Merck & Co., Inc. 4"-Keto-and 4"-amino-4"-deoxy avermectin compounds and substituted amino derivatives thereof
EP0192060B1 (de) 1985-02-04 1991-09-18 Nihon Bayer Agrochem K.K. Heterocyclische Verbindungen
EP0237482A1 (de) 1986-03-06 1987-09-16 Ciba-Geigy Ag C(29)-Carbonyloxi-milbemycin-Derivate zur Bekämpfung von tier- und pflanzenparasitären Schädlingen
BR8701302A (pt) 1986-03-25 1987-12-22 Sankyo Co Compostos macrolideos,sua preparacao e seu uso
ES2039258T3 (es) 1986-07-02 1993-09-16 Ciba-Geigy Ag Pesticidas.
US4855317A (en) 1987-03-06 1989-08-08 Ciba-Geigy Corporation Insecticides and parasiticides
US4871719A (en) 1987-03-24 1989-10-03 Ciba-Geigy Corporation Composition for controlling parasites in productive livestock
US4874749A (en) 1987-07-31 1989-10-17 Merck & Co., Inc. 4"-Deoxy-4-N-methylamino avermectin Bla/Blb
EP0319142B1 (en) 1987-11-03 1994-04-06 Beecham Group Plc Intermediates for the preparation of anthelmintic macrolide antibiotics
NZ232422A (en) 1989-02-16 1992-11-25 Merck & Co Inc 13-ketal milbemycin derivatives and parasiticides
NZ247278A (en) 1991-02-12 1995-03-28 Ancare Distributors Veterinary anthelmintic drench comprising a suspension of praziquantel in a liquid carrier
US5330768A (en) 1991-07-05 1994-07-19 Massachusetts Institute Of Technology Controlled drug delivery using polymer/pluronic blends
US5345377A (en) 1992-10-30 1994-09-06 Electric Power Research Institute, Inc. Harmonic controller for an active power line conditioner
GB9300883D0 (en) 1993-01-18 1993-03-10 Pfizer Ltd Antiparasitic agents
AUPM969994A0 (en) 1994-11-28 1994-12-22 Virbac S.A. Equine anthelmintic formulations
US6207647B1 (en) 1997-07-18 2001-03-27 Smithkline Beecham Corporation RatA
ES2359973T3 (es) * 1998-03-19 2011-05-30 MERCK SHARP & DOHME CORP. Composiciones poliméricas líquidas para la liberación controlada de sustancias bioactivas.
CN102558082B (zh) 2004-03-05 2015-09-30 日产化学工业株式会社 异噁唑啉取代苯甲酰胺化合物的制备中间体
US8362086B2 (en) 2005-08-19 2013-01-29 Merial Limited Long acting injectable formulations
AU2006285613B2 (en) 2005-09-02 2011-11-17 Nissan Chemical Corporation Isoxazoline-substituted benzamide compound and harmful organism-controlling agent
US20090143410A1 (en) 2005-12-14 2009-06-04 Kanu Maganbhai Patel Isoxazolines for Controlling Invertebrate Pests
TW200803740A (en) 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
TWI412322B (zh) 2005-12-30 2013-10-21 Du Pont 控制無脊椎害蟲之異唑啉
AU2007240954A1 (en) 2006-04-20 2007-11-01 E. I. Du Pont De Nemours And Company Pyrazolines for controlling invertebrate pests
JP2008044880A (ja) 2006-08-15 2008-02-28 Bayer Cropscience Ag 殺虫性イソオキサゾリン類
JP5256753B2 (ja) 2007-03-29 2013-08-07 住友化学株式会社 イソオキサゾリン化合物とその有害生物防除用途
BRPI0810196A2 (pt) 2007-04-10 2011-12-06 Bayer Cropscience Ag inseticidas de derivados de aril isoxazolina
BRPI0809770B8 (pt) 2007-06-13 2022-12-06 Du Pont Composto e composição para controlar uma praga de invertebrados
TWI430995B (zh) * 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
TWI556741B (zh) * 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
KR20100075996A (ko) 2007-10-03 2010-07-05 이 아이 듀폰 디 네모아 앤드 캄파니 무척추 해충의 방제를 위한 나프탈렌 이속사졸린 화합물
WO2010003923A1 (en) 2008-07-09 2010-01-14 Basf Se Pestcidal active mixtures comprising isoxazoline compounds i
CA2747060A1 (en) * 2008-12-18 2010-07-15 Novartis Ag Isoxazolines derivatives and their use as pesticide
EA021522B9 (ru) * 2009-12-17 2016-08-31 Мериал Лимитед Противопаразитарные дигидроазоловые соединения и содержащие их композиции
PL2576523T3 (pl) 2010-05-27 2016-08-31 Du Pont Krystaliczna postać 4-[5 - [3 -chloro-5 -(trifluorometylo)fenylo] -4,5 -dihydro-5 -(trifluorometylo)-3 - izoksazolilo]-n-[2-okso-2-[(2,2,2-trifluoroetylo)amino]etylo]-1- naftalenokarboksyamidu
DK178277B1 (da) * 2010-06-18 2015-10-26 Novartis Tiergesundheit Ag Diaryloxazolinforbindelser til bekæmpelse af fiskelus
KR101920476B1 (ko) 2010-12-27 2018-11-21 인터벳 인터내셔널 비.브이. 글리코푸롤을 포함하는 국소 적용 이속사졸린 제제
JP2014505089A (ja) * 2011-02-10 2014-02-27 ノバルティス アーゲー 無脊椎有害動物を防除するためのイソオキサゾリン誘導体
ES2542409T3 (es) 2011-03-10 2015-08-05 Novartis Tiergesundheit Ag Derivados de isoxazol
WO2012120399A1 (en) 2011-03-10 2012-09-13 Pfizer Inc. Spirocyclic isoxazoline derivatives as antiparasitic agents
RS61048B1 (sr) * 2011-09-12 2020-12-31 Boehringer Ingelheim Animal Health Usa Inc Paraziticidne kompozicije koje sadrže izoksazolin aktivni agens, postupak i njihove primene
AR088669A1 (es) * 2011-11-21 2014-06-25 Lilly Co Eli Derivados de dihidrodibenzo[c][1,2]oxaborol y dihidroisoxazol utiles para el control de ectoparasitos
AR088668A1 (es) * 2011-11-21 2014-06-25 Lilly Co Eli Moleculas pequeñas que contienen boro
ES2978407T3 (es) * 2011-12-02 2024-09-12 Boehringer Ingelheim Vetmedica Gmbh Formulaciones de moxidectina inyectables de acción prolongada
ES2720201T3 (es) 2012-02-06 2019-07-18 Merial Inc Composiciones parasiticidas orales veterinarias que comprenden agentes activos de acción sistémica y usos de las mismas
ES2748631T3 (es) * 2012-09-07 2020-03-17 Zoetis Services Llc Combinaciones parasiticidas de isoxazolina espirocíclica
EP2892901A1 (en) 2012-09-07 2015-07-15 Zoetis LLC Spirocyclic isoxazolines as antiparasitic agents
US20160081986A1 (en) 2013-05-20 2016-03-24 Zoetis Services Llc Long-acting spiro-isoxazoline antiparasitic compositions
EP3052080B1 (en) * 2013-09-30 2025-06-25 Zoetis Services LLC Long-acting spiro-isoxazoline formulations

Also Published As

Publication number Publication date
KR20170134700A (ko) 2017-12-06
IL254813B (en) 2020-03-31
EP3280413A1 (en) 2018-02-14
SG11201708068PA (en) 2017-10-30
MX2017012848A (es) 2018-01-15
CN108055825B (zh) 2021-03-30
EA202090762A1 (ru) 2020-09-08
US20210299104A1 (en) 2021-09-30
CO2017010065A2 (es) 2018-01-05
CA2981797A1 (en) 2016-10-13
WO2016164487A1 (en) 2016-10-13
UY36610A (es) 2016-10-31
CL2017002536A1 (es) 2018-04-20
KR102593069B1 (ko) 2023-10-23
AR104212A1 (es) 2017-07-05
AU2020210266A1 (en) 2020-08-20
IL254813A0 (en) 2017-12-31
EA201792235A1 (ru) 2018-01-31
JP2021050206A (ja) 2021-04-01
SG10201912724SA (en) 2020-02-27
BR112017021073A2 (pt) 2018-07-03
JP2018510897A (ja) 2018-04-19
CA2981797C (en) 2023-11-21
NZ736374A (en) 2024-02-23
AU2022202035A1 (en) 2022-04-14
JP6824900B2 (ja) 2021-02-03
AU2020210266B2 (en) 2022-03-10
CN108055825A (zh) 2018-05-18
US20170020848A1 (en) 2017-01-26
AU2016246598A1 (en) 2017-11-02
EA036272B1 (ru) 2020-10-21
AU2016246598B2 (en) 2020-07-23

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