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MX2022007117A - Anticuerpo con especificidad de enlace para la il-13 humana. - Google Patents

Anticuerpo con especificidad de enlace para la il-13 humana.

Info

Publication number
MX2022007117A
MX2022007117A MX2022007117A MX2022007117A MX2022007117A MX 2022007117 A MX2022007117 A MX 2022007117A MX 2022007117 A MX2022007117 A MX 2022007117A MX 2022007117 A MX2022007117 A MX 2022007117A MX 2022007117 A MX2022007117 A MX 2022007117A
Authority
MX
Mexico
Prior art keywords
human
antibody
antibody molecules
binding specificity
specificity
Prior art date
Application number
MX2022007117A
Other languages
English (en)
Inventor
Ralph Adams
Daniel John Lightwood
Roger Thomas Palframan
Original Assignee
UCB Biopharma SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UCB Biopharma SRL filed Critical UCB Biopharma SRL
Publication of MX2022007117A publication Critical patent/MX2022007117A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Dermatology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La invención se refiere a moléculas de anticuerpos que tienen especificidad para los determinantes antigénicos de la IL-13 humana, a los usos terapéuticos de las moléculas de anticuerpos, y a los métodos para producir las moléculas de anticuerpos.
MX2022007117A 2019-12-20 2020-12-18 Anticuerpo con especificidad de enlace para la il-13 humana. MX2022007117A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1919062.8A GB201919062D0 (en) 2019-12-20 2019-12-20 Antibody
PCT/EP2020/087053 WO2021123190A1 (en) 2019-12-20 2020-12-18 Antibody with binding specificity for human il-13.

Publications (1)

Publication Number Publication Date
MX2022007117A true MX2022007117A (es) 2022-07-11

Family

ID=69322674

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022007117A MX2022007117A (es) 2019-12-20 2020-12-18 Anticuerpo con especificidad de enlace para la il-13 humana.

Country Status (14)

Country Link
US (1) US20230084464A1 (es)
EP (1) EP4077382A1 (es)
JP (1) JP7710446B2 (es)
KR (1) KR20220117305A (es)
CN (1) CN114829398B (es)
AU (1) AU2020406155A1 (es)
BR (1) BR112022011619A2 (es)
CA (1) CA3164231A1 (es)
CL (1) CL2022001684A1 (es)
CO (1) CO2022008268A2 (es)
GB (1) GB201919062D0 (es)
IL (1) IL293812A (es)
MX (1) MX2022007117A (es)
WO (1) WO2021123190A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114617962A (zh) 2016-04-27 2022-06-14 艾伯维公司 使用抗-il-13抗体治疗il-13活性在其中有害的疾病的方法

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Also Published As

Publication number Publication date
JP2023507282A (ja) 2023-02-22
US20230084464A1 (en) 2023-03-16
KR20220117305A (ko) 2022-08-23
AU2020406155A1 (en) 2022-08-04
JP7710446B2 (ja) 2025-07-18
CO2022008268A2 (es) 2022-06-21
CN114829398A (zh) 2022-07-29
IL293812A (en) 2022-08-01
CA3164231A1 (en) 2021-06-24
EP4077382A1 (en) 2022-10-26
WO2021123190A1 (en) 2021-06-24
BR112022011619A2 (pt) 2022-12-20
CL2022001684A1 (es) 2023-05-26
GB201919062D0 (en) 2020-02-05
CN114829398B (zh) 2025-05-27

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