MX2022006444A - Linfocitos t activados por bite ex vivo. - Google Patents
Linfocitos t activados por bite ex vivo.Info
- Publication number
- MX2022006444A MX2022006444A MX2022006444A MX2022006444A MX2022006444A MX 2022006444 A MX2022006444 A MX 2022006444A MX 2022006444 A MX2022006444 A MX 2022006444A MX 2022006444 A MX2022006444 A MX 2022006444A MX 2022006444 A MX2022006444 A MX 2022006444A
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- Prior art keywords
- cells
- methods
- cancer
- immune
- cell
- Prior art date
Links
- 210000001744 T-lymphocyte Anatomy 0.000 title abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 6
- 210000004027 cell Anatomy 0.000 abstract 5
- 238000000034 method Methods 0.000 abstract 5
- 201000011510 cancer Diseases 0.000 abstract 4
- 210000002865 immune cell Anatomy 0.000 abstract 2
- 239000012642 immune effector Substances 0.000 abstract 2
- 229940121354 immunomodulator Drugs 0.000 abstract 2
- 238000011861 anti-inflammatory therapy Methods 0.000 abstract 1
- 230000022534 cell killing Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002489 hematologic effect Effects 0.000 abstract 1
- 230000002147 killing effect Effects 0.000 abstract 1
- 230000001394 metastastic effect Effects 0.000 abstract 1
- 206010061289 metastatic neoplasm Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000004043 responsiveness Effects 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
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- C12N5/06—Animal cells or tissues; Human cells or tissues
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Abstract
La generación y la identificación de células efectoras inmunitarias muy eficaces en términos de actividad de destrucción de células diana se puede potenciar mediante la optimización de la proximidad entre una célula diana y una célula efectora inmunitaria. Los linfocitos T destructores del cáncer descritos en el presente documento pueden proporcionar terapias altamente eficaces para diversos tipos de cáncer, por ejemplo, cánceres sólidos, cánceres hematológicos y formas metastásicas de los mismos. En el presente documento, se proporcionan métodos ex vivo de generación de linfocitos T destructores del cáncer, composiciones que comprenden dichas células inmunitarias; métodos de uso de las células, métodos para seleccionar agentes óptimos para potenciar la actividad de destrucción de las células diana, métodos para seleccionar una célula inmunitaria optimizada y métodos de uso de este enfoque para evaluar la capacidad de respuesta del paciente a otras terapias contra el cáncer.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662321964P | 2016-04-13 | 2016-04-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2022006444A true MX2022006444A (es) | 2022-06-22 |
Family
ID=58669776
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018012488A MX392707B (es) | 2016-04-13 | 2017-04-12 | LINFOCITOS T ACTIVADOS POR BiTE EX VIVO. |
| MX2022006444A MX2022006444A (es) | 2016-04-13 | 2018-10-11 | Linfocitos t activados por bite ex vivo. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018012488A MX392707B (es) | 2016-04-13 | 2017-04-12 | LINFOCITOS T ACTIVADOS POR BiTE EX VIVO. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20190218515A1 (es) |
| EP (1) | EP3445391B1 (es) |
| JP (2) | JP7038353B2 (es) |
| KR (1) | KR20180133442A (es) |
| CN (2) | CN109789195A (es) |
| AU (2) | AU2017249698B2 (es) |
| CA (1) | CA3020830A1 (es) |
| IL (2) | IL295538B2 (es) |
| MX (2) | MX392707B (es) |
| SG (1) | SG11201808909WA (es) |
| WO (1) | WO2017178572A1 (es) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2012000086A (es) | 2009-06-26 | 2012-06-12 | Soricimed Biopharma Inc | Peptidos derivados de soricidi y metodos para la la deteccion de canceres trpv-6 y suministro de farmaco. |
| KR20190006952A (ko) * | 2016-03-31 | 2019-01-21 | 라이언 티씨알 피티이. 리미티드 | 외인성 바이러스-특이적 t 세포 수용체 (tcr)를 발현하는 비-활성화된 t 세포 |
| TW202515920A (zh) * | 2017-04-11 | 2025-04-16 | 美商因荷布瑞克斯生物科學公司 | 具有經受限cd3結合的多重特異性多肽構築體及使用其之方法 |
| WO2019077062A1 (en) * | 2017-10-18 | 2019-04-25 | Vivia Biotech, S.L. | C-CELLS ACTIVATED BY BIT |
| US20200384069A1 (en) * | 2017-12-01 | 2020-12-10 | Soricimed Biopharma Inc. | Trpv6 inhibitors and combination therapies for treating cancers |
| CA3089127A1 (en) * | 2018-02-02 | 2019-08-08 | Wake Forest University Health Sciences | Organoids related to immunotherapy and methods of preparing and using the same |
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