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MX2022003814A - Compuestos antibacterianos de 4-quinolinona. - Google Patents

Compuestos antibacterianos de 4-quinolinona.

Info

Publication number
MX2022003814A
MX2022003814A MX2022003814A MX2022003814A MX2022003814A MX 2022003814 A MX2022003814 A MX 2022003814A MX 2022003814 A MX2022003814 A MX 2022003814A MX 2022003814 A MX2022003814 A MX 2022003814A MX 2022003814 A MX2022003814 A MX 2022003814A
Authority
MX
Mexico
Prior art keywords
quinolinone
antibacterial compounds
compounds
antibacterial
tuberculosis
Prior art date
Application number
MX2022003814A
Other languages
English (en)
Inventor
Jérôme Émile Georges Guillemont
Magali Madeleine Simone Motte
LAMMENS Godelieve Maria J
Dirk Antonie Lamprecht
Steffen Friedrich Walter Weidner
Ellen Anita Lanckacker
Original Assignee
Janssen Sciences Ireland Unlimited Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Sciences Ireland Unlimited Co filed Critical Janssen Sciences Ireland Unlimited Co
Publication of MX2022003814A publication Critical patent/MX2022003814A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyridine Compounds (AREA)

Abstract

La presente invención se refiere a los siguientes compuestos (ver Fórmula) donde los componentes integrantes son como se definen en la descripción, y donde los compuestos pueden ser útiles como medicamentos, por ejemplo, para su uso en el tratamiento de la tuberculosis (por ejemplo, combinados).
MX2022003814A 2019-09-30 2020-09-29 Compuestos antibacterianos de 4-quinolinona. MX2022003814A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19200366 2019-09-30
PCT/EP2020/077173 WO2021063914A1 (en) 2019-09-30 2020-09-29 4-quinolinone antibacterial compounds

Publications (1)

Publication Number Publication Date
MX2022003814A true MX2022003814A (es) 2022-05-06

Family

ID=68104401

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022003814A MX2022003814A (es) 2019-09-30 2020-09-29 Compuestos antibacterianos de 4-quinolinona.

Country Status (10)

Country Link
US (1) US20220389008A1 (es)
EP (1) EP4038067A1 (es)
JP (1) JP2022550784A (es)
KR (1) KR20220071199A (es)
CN (1) CN114450288A (es)
AU (1) AU2020358643A1 (es)
BR (1) BR112022005068A2 (es)
CA (1) CA3149988A1 (es)
MX (1) MX2022003814A (es)
WO (1) WO2021063914A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2020360560A1 (en) * 2019-09-30 2022-03-10 Janssen Sciences Ireland Unlimited Company Antibacterial compounds
EP4296674A1 (en) 2022-06-20 2023-12-27 Université Toulouse III - Paul Sabatier Innovative molecules decreasing virulence of mycobacterium for the treatment of tuberculosis

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP2421A (en) 2002-07-25 2012-06-08 Janssen Pharmaceutica Nl Quinoline derivatives and their use as mycobacterial inhibitors.
CN100488960C (zh) * 2006-03-09 2009-05-20 中国药科大学 2-位取代的喹诺酮类化合物及其在制药中的应用
ES2572387T3 (es) * 2010-03-18 2016-05-31 Pasteur Institut Korea Compuestos anti-infecciosos
GB201020076D0 (en) 2010-11-26 2011-01-12 Liverpool School Tropical Medicine Antimalarial compounds
ES2883565T3 (es) * 2013-08-02 2021-12-09 Pasteur Institut Korea Compuestos antiinfecciosos
EP3316968A1 (en) 2015-07-02 2018-05-09 Janssen Sciences Ireland UC Antibacterial compounds
GB201522232D0 (en) * 2015-12-16 2016-01-27 Liverpool School Tropical Medicine Combination product
EA201990044A1 (ru) 2016-06-16 2019-05-31 Янссен Сайенсиз Айрлэнд Анлимитед Компани Гетероциклические соединения в качестве антибактериальных средств
AU2017286368B2 (en) 2016-06-16 2021-02-25 Janssen Sciences Ireland Unlimited Company Heterocyclic compounds as antibacterials
WO2018084809A1 (en) * 2016-11-02 2018-05-11 Nanyang Technological University Methods for the treatment or prevention of mycobacterial infections
AU2020360560A1 (en) * 2019-09-30 2022-03-10 Janssen Sciences Ireland Unlimited Company Antibacterial compounds

Also Published As

Publication number Publication date
CN114450288A (zh) 2022-05-06
AU2020358643A1 (en) 2022-05-26
WO2021063914A1 (en) 2021-04-08
BR112022005068A2 (pt) 2022-09-06
JP2022550784A (ja) 2022-12-05
CA3149988A1 (en) 2021-04-08
KR20220071199A (ko) 2022-05-31
US20220389008A1 (en) 2022-12-08
EP4038067A1 (en) 2022-08-10

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