MX2021011971A - Proceso para preparar cicloserinas sustituidas. - Google Patents
Proceso para preparar cicloserinas sustituidas.Info
- Publication number
- MX2021011971A MX2021011971A MX2021011971A MX2021011971A MX2021011971A MX 2021011971 A MX2021011971 A MX 2021011971A MX 2021011971 A MX2021011971 A MX 2021011971A MX 2021011971 A MX2021011971 A MX 2021011971A MX 2021011971 A MX2021011971 A MX 2021011971A
- Authority
- MX
- Mexico
- Prior art keywords
- sub
- sup
- aryl
- substituted
- preparation
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000001188 haloalkyl group Chemical group 0.000 abstract 2
- 239000000543 intermediate Substances 0.000 abstract 2
- DYDCUQKUCUHJBH-UWTATZPHSA-N D-Cycloserine Chemical class N[C@@H]1CONC1=O DYDCUQKUCUHJBH-UWTATZPHSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000004438 haloalkoxy group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/12—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
La presente invención se refiere a procesos para preparar compuestos de tipo cicloserina sustituida de fórmula (I) (ver Fórmula) donde R1 es alquilo C1-C8, haloalquilo C1-C8, cicloalquilo C3-C6, arilo o arilo sustituido con de uno a cinco R11, o aril-(alquileno C1-C4) o aril-(alquileno C1-C4) sustituido con de uno a cinco R11; y cada R11 es independientemente alquilo C1-C4, haloalquilo C1-C4, alcoxi C1-C4, haloalcoxi C1-C4, ciano o halógeno. La invención también se refiere a intermedios producidos mediante los procesos. Los compuestos de fórmula (I) son intermedios útiles para producir compuestos en los campos agrícola y farmacéutico.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14166654 | 2014-04-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2021011971A true MX2021011971A (es) | 2021-11-03 |
Family
ID=50693448
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016014119A MX388328B (es) | 2014-04-30 | 2015-04-30 | Proceso para preparar cicloserinas sustituidas. |
| MX2021011971A MX2021011971A (es) | 2014-04-30 | 2016-10-27 | Proceso para preparar cicloserinas sustituidas. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016014119A MX388328B (es) | 2014-04-30 | 2015-04-30 | Proceso para preparar cicloserinas sustituidas. |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US9643938B2 (es) |
| EP (1) | EP3137449B1 (es) |
| JP (1) | JP6523334B2 (es) |
| CN (3) | CN114031572B (es) |
| BR (2) | BR112016025076B1 (es) |
| DK (1) | DK3137449T3 (es) |
| ES (1) | ES2774363T3 (es) |
| HU (1) | HUE049170T2 (es) |
| IL (1) | IL248267B (es) |
| MX (2) | MX388328B (es) |
| PL (1) | PL3137449T3 (es) |
| SI (1) | SI3137449T1 (es) |
| WO (1) | WO2015166094A1 (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3137449B1 (en) * | 2014-04-30 | 2019-12-18 | Syngenta Participations AG | Process for the preparation of substituted cycloserines |
| US12497370B2 (en) | 2019-12-18 | 2025-12-16 | Elanco Tiergesundheit Ag | Isoxazoline derivatives |
| CN114014776B (zh) * | 2021-12-09 | 2024-03-12 | 西安鸿钧睿泽新材料科技有限公司 | 一种具有低全球变暖潜值的化合物、制备方法及其应用 |
| AR129405A1 (es) | 2022-05-30 | 2024-08-21 | Syngenta Crop Protection Ag | Procedimiento para la preparación de 2-oxazolidinonas 4-sustituidas |
| WO2024033374A1 (en) | 2022-08-11 | 2024-02-15 | Syngenta Crop Protection Ag | Novel arylcarboxamide or arylthioamide compounds |
| WO2024089216A1 (en) | 2022-10-27 | 2024-05-02 | Syngenta Crop Protection Ag | Novel sulfur-containing heteroaryl carboxamide compounds |
| EP4634152A1 (en) | 2022-12-15 | 2025-10-22 | Syngenta Crop Protection AG | Novel bicyclic-carboxamide compounds useful as pesticides |
| KR20250151434A (ko) | 2023-02-24 | 2025-10-21 | 신젠타 크롭 프로텍션 아게 | 이속사졸린 유도체의 제조 공정 |
| WO2026021962A1 (en) | 2024-07-26 | 2026-01-29 | Basf Se | Process for the preparation of an aqueous solution comprising n-alkylhydroxylamine |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB799066A (en) * | 1955-11-17 | 1958-07-30 | Hoffmann La Roche | Process for the manufacture of isoxazolidone compounds |
| CH488719A (de) * | 1967-06-26 | 1970-04-15 | Eprova Ag | Verfahren zur Herstellung von Cycloserin (D-4-Amino-3-isoxazolidinon) |
| JPS5714337B2 (es) * | 1973-02-23 | 1982-03-24 | ||
| WO1996030381A1 (en) * | 1995-03-28 | 1996-10-03 | Novo Nordisk A/S | Immunosuppressive agents |
| CA2689607A1 (en) * | 2007-06-06 | 2008-12-18 | Tyrogenex, Inc. | Kinase inhibitor compounds |
| US8952175B2 (en) * | 2007-06-27 | 2015-02-10 | Nissan Chemical Industries, Ltd. | Method for production of 3-hydroxypropan-1-one compound, method for production of 2-propen-1-one compound and method for production of isoxazoline compound |
| TWI487486B (zh) * | 2009-12-01 | 2015-06-11 | Syngenta Participations Ag | 以異唑啉衍生物為主之殺蟲化合物 |
| KR20120131646A (ko) * | 2011-05-26 | 2012-12-05 | 주식회사 참조아 | 이속사졸리디논 유도체인 ｄ-시클로세린의 제조방법 |
| AR086587A1 (es) * | 2011-05-31 | 2014-01-08 | Syngenta Participations Ag | Compuestos insecticidas |
| EP3137449B1 (en) * | 2014-04-30 | 2019-12-18 | Syngenta Participations AG | Process for the preparation of substituted cycloserines |
-
2015
- 2015-04-30 EP EP15722685.3A patent/EP3137449B1/en active Active
- 2015-04-30 CN CN202111372808.9A patent/CN114031572B/zh active Active
- 2015-04-30 WO PCT/EP2015/059612 patent/WO2015166094A1/en not_active Ceased
- 2015-04-30 HU HUE15722685A patent/HUE049170T2/hu unknown
- 2015-04-30 CN CN201580022794.4A patent/CN106255681B/zh active Active
- 2015-04-30 DK DK15722685.3T patent/DK3137449T3/da active
- 2015-04-30 ES ES15722685T patent/ES2774363T3/es active Active
- 2015-04-30 PL PL15722685T patent/PL3137449T3/pl unknown
- 2015-04-30 BR BR112016025076-1A patent/BR112016025076B1/pt active IP Right Grant
- 2015-04-30 SI SI201531115T patent/SI3137449T1/sl unknown
- 2015-04-30 CN CN201810808594.7A patent/CN108822053A/zh active Pending
- 2015-04-30 JP JP2016565167A patent/JP6523334B2/ja active Active
- 2015-04-30 MX MX2016014119A patent/MX388328B/es unknown
- 2015-04-30 US US15/307,386 patent/US9643938B2/en active Active
- 2015-04-30 BR BR122021004312-4A patent/BR122021004312B1/pt active IP Right Grant
-
2016
- 2016-10-09 IL IL248267A patent/IL248267B/en active IP Right Grant
- 2016-10-27 MX MX2021011971A patent/MX2021011971A/es unknown
-
2017
- 2017-04-03 US US15/477,159 patent/US9815803B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20170204072A1 (en) | 2017-07-20 |
| CN106255681B (zh) | 2019-11-22 |
| PL3137449T3 (pl) | 2020-07-27 |
| WO2015166094A1 (en) | 2015-11-05 |
| JP6523334B2 (ja) | 2019-05-29 |
| SI3137449T1 (sl) | 2020-04-30 |
| IL248267B (en) | 2019-07-31 |
| BR122021004312B1 (pt) | 2022-02-08 |
| CN114031572B (zh) | 2025-07-08 |
| BR112016025076B1 (pt) | 2022-03-03 |
| HUE049170T2 (hu) | 2020-09-28 |
| CN106255681A (zh) | 2016-12-21 |
| ES2774363T3 (es) | 2020-07-20 |
| IL248267A0 (en) | 2016-11-30 |
| CN114031572A (zh) | 2022-02-11 |
| EP3137449A1 (en) | 2017-03-08 |
| BR112016025076A2 (pt) | 2018-07-10 |
| EP3137449B1 (en) | 2019-12-18 |
| MX2016014119A (es) | 2017-02-09 |
| DK3137449T3 (da) | 2020-03-02 |
| US9643938B2 (en) | 2017-05-09 |
| US9815803B2 (en) | 2017-11-14 |
| MX388328B (es) | 2025-03-19 |
| JP2017518272A (ja) | 2017-07-06 |
| CN108822053A (zh) | 2018-11-16 |
| US20170044116A1 (en) | 2017-02-16 |
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