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MX2021008094A - Metodos y composiciones para el tratamiento del cancer. - Google Patents

Metodos y composiciones para el tratamiento del cancer.

Info

Publication number
MX2021008094A
MX2021008094A MX2021008094A MX2021008094A MX2021008094A MX 2021008094 A MX2021008094 A MX 2021008094A MX 2021008094 A MX2021008094 A MX 2021008094A MX 2021008094 A MX2021008094 A MX 2021008094A MX 2021008094 A MX2021008094 A MX 2021008094A
Authority
MX
Mexico
Prior art keywords
cancer
compositions
treatment
methods
protein
Prior art date
Application number
MX2021008094A
Other languages
English (en)
Inventor
Gregory A Demopulos
Michael Cicirelli
George A Gaitanaris
Marc A Gavin
Alexander Gragerov
Thomas L Little
Rene Onrust
Neil S Cutshall
Original Assignee
Omeros Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omeros Corp filed Critical Omeros Corp
Publication of MX2021008094A publication Critical patent/MX2021008094A/es

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    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/17Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
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    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
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    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • A61K31/522Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
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    • A61K31/53Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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Abstract

La presente divulgacion se refiere a compuestos, composiciones y metodos para el tratamiento de diversas enfermedades y/o padecimientos relacionados con el receptor acoplado a proteínas G 174 (p.ej., varios tipos de cancer).
MX2021008094A 2019-01-11 2020-01-10 Metodos y composiciones para el tratamiento del cancer. MX2021008094A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962791591P 2019-01-11 2019-01-11
US201962886235P 2019-08-13 2019-08-13
US201962936223P 2019-11-15 2019-11-15
US201962946631P 2019-12-11 2019-12-11
PCT/US2020/013183 WO2020146795A1 (en) 2019-01-11 2020-01-10 Methods and compositions for treating cancer

Publications (1)

Publication Number Publication Date
MX2021008094A true MX2021008094A (es) 2021-09-21

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Application Number Title Priority Date Filing Date
MX2021008094A MX2021008094A (es) 2019-01-11 2020-01-10 Metodos y composiciones para el tratamiento del cancer.

Country Status (15)

Country Link
US (2) US20200345725A1 (es)
EP (1) EP3908601B1 (es)
JP (1) JP7625524B2 (es)
KR (1) KR20210114963A (es)
CN (1) CN113727999A (es)
AU (1) AU2020205753B2 (es)
BR (1) BR112021012685A2 (es)
CA (1) CA3126735A1 (es)
CL (1) CL2021001818A1 (es)
IL (1) IL284745B2 (es)
JO (1) JOP20210164A1 (es)
MX (1) MX2021008094A (es)
SG (1) SG11202106963YA (es)
WO (1) WO2020146795A1 (es)
ZA (1) ZA202104870B (es)

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US20240391990A1 (en) * 2021-09-03 2024-11-28 Nan TANG Bi-functional fusion protein and uses thereof
WO2023055942A1 (en) * 2021-09-29 2023-04-06 The Johns Hopkins University Methods and compositions to augment efficacy and reduce toxicity of non-engrafting, cd8-depleted allogenic donor lymphocyte infusions
WO2024044659A1 (en) * 2022-08-24 2024-02-29 Tectonic Therapeutic, Inc. Constitutively active g protein-coupled receptor compositions and methods of use thereof
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CN118403075B (zh) * 2024-04-30 2025-06-13 暨南大学 偏钨酸钠在制备治疗或预防流感病毒感染的药物中的应用
WO2025259871A1 (en) 2024-06-14 2025-12-18 Gilead Sciences, Inc. Anti-ccr8 antibodies and uses thereof
CN119745799B (zh) * 2024-12-05 2025-10-24 浙江大学 一种调节atp-ado轴解除免疫抑制的超声激活型脂质体及其应用

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