MX2021000614A - Células diferenciadas de células pluripotentes inmunodiseñadas. - Google Patents
Células diferenciadas de células pluripotentes inmunodiseñadas.Info
- Publication number
- MX2021000614A MX2021000614A MX2021000614A MX2021000614A MX2021000614A MX 2021000614 A MX2021000614 A MX 2021000614A MX 2021000614 A MX2021000614 A MX 2021000614A MX 2021000614 A MX2021000614 A MX 2021000614A MX 2021000614 A MX2021000614 A MX 2021000614A
- Authority
- MX
- Mexico
- Prior art keywords
- cells
- immunoengineered
- pluripotent
- differentiated
- hypoimmune
- Prior art date
Links
- 210000004027 cell Anatomy 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000000747 cardiac effect Effects 0.000 abstract 1
- 230000012202 endocytosis Effects 0.000 abstract 1
- 230000003511 endothelial effect Effects 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000001537 neural effect Effects 0.000 abstract 1
- 230000000242 pagocytic effect Effects 0.000 abstract 1
- 210000004694 pigment cell Anatomy 0.000 abstract 1
- 239000000790 retinal pigment Substances 0.000 abstract 1
- 210000000130 stem cell Anatomy 0.000 abstract 1
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- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
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Abstract
La invención proporciona células pluripotentes hipoinmunogénicas "listas para usar" universalmente aceptables y células cardíacas, endoteliales, neurales, de islotes o de pigmento de la retina de las mismas. Tales células hipoinmunes se utilizan para tratar a los pacientes que las necesitan. Las células carecen de los principales antígenos inmunes que desencadenan respuestas inmunes y están diseñadas para evitar la endocitosis fagocítica.
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862698973P | 2018-07-17 | 2018-07-17 | |
| US201862698965P | 2018-07-17 | 2018-07-17 | |
| US201862698984P | 2018-07-17 | 2018-07-17 | |
| US201862698981P | 2018-07-17 | 2018-07-17 | |
| US201862698978P | 2018-07-17 | 2018-07-17 | |
| PCT/US2019/042117 WO2020018615A2 (en) | 2018-07-17 | 2019-07-17 | Cells differentiated from immunoengineered pluripotent cells |
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| MX2025004255A MX2025004255A (es) | 2018-07-17 | 2021-01-15 | Celulas diferenciadas de celulas pluripotentes inmunodise?adas |
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| MX2025004255A MX2025004255A (es) | 2018-07-17 | 2021-01-15 | Celulas diferenciadas de celulas pluripotentes inmunodise?adas |
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| EP (1) | EP3824074A4 (es) |
| JP (2) | JP2021530232A (es) |
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| IL (2) | IL314721A (es) |
| MX (2) | MX2021000614A (es) |
| SG (1) | SG11202100157YA (es) |
| WO (1) | WO2020018615A2 (es) |
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| MX2021000614A (es) * | 2018-07-17 | 2021-07-02 | Univ California | Células diferenciadas de células pluripotentes inmunodiseñadas. |
| US11162079B2 (en) | 2019-05-10 | 2021-11-02 | The Regents Of The University Of California | Blood type O Rh-hypo-immunogenic pluripotent cells |
| MX2021013713A (es) | 2019-05-10 | 2021-12-10 | Univ California | Celulas pluripotentes modificadas. |
| GB2584664B (en) * | 2019-06-10 | 2023-05-24 | Newcells Biotech Ltd | Improved retinal organoids and methods of making the same |
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| US20230058557A1 (en) * | 2020-01-15 | 2023-02-23 | The Regents Of The University Of California | Transplanted cell protection via inhibition of polymorphonuclear cells |
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| BR112022021617A2 (pt) * | 2020-04-27 | 2023-01-03 | Sana Biotechnology Inc | Dosagem repetida de células hipoimunogênicas |
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| JP2024535677A (ja) | 2021-08-11 | 2024-10-02 | サナ バイオテクノロジー,インコーポレイテッド | 即時血液媒介性炎症反応を減少させるための同種細胞療法を目的とした遺伝子改変細胞 |
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| MX2021000614A (es) * | 2018-07-17 | 2021-07-02 | Univ California | Células diferenciadas de células pluripotentes inmunodiseñadas. |
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| BR112021000637A2 (pt) | 2021-04-13 |
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