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MX2020008275A - Metodos para tratar trastornos mitocondriales. - Google Patents

Metodos para tratar trastornos mitocondriales.

Info

Publication number
MX2020008275A
MX2020008275A MX2020008275A MX2020008275A MX2020008275A MX 2020008275 A MX2020008275 A MX 2020008275A MX 2020008275 A MX2020008275 A MX 2020008275A MX 2020008275 A MX2020008275 A MX 2020008275A MX 2020008275 A MX2020008275 A MX 2020008275A
Authority
MX
Mexico
Prior art keywords
sulforaphane
methods
mitochondrial disorders
treating mitochondrial
present disclosure
Prior art date
Application number
MX2020008275A
Other languages
English (en)
Inventor
Shaoyun Liu
Original Assignee
Shaoyun Liu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shaoyun Liu filed Critical Shaoyun Liu
Publication of MX2020008275A publication Critical patent/MX2020008275A/es

Links

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
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    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/26—Cyanate or isocyanate esters; Thiocyanate or isothiocyanate esters
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
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    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
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    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
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    • A—HUMAN NECESSITIES
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    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Psychology (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Obesity (AREA)
  • Botany (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)

Abstract

La presente descripción proporciona composiciones y métodos farmacéuticos y nutracéuticos para el tratamiento de trastornos mitocondriales. Las composiciones farmacéuticas o nutracéuticas incluyen un sulforafano estabilizado, como el complejo de sulforafano-ciclodextrina, que incrementa la eficacia, la actividad biológica y la estabilidad del sulforafano aislado. La presente descripción también incluye el uso de sulforafano estabilizado como un agente terapéutico eficaz para el tratamiento de trastornos mitocondriales, tales como la miopatía mitocondrial.
MX2020008275A 2018-02-09 2019-02-08 Metodos para tratar trastornos mitocondriales. MX2020008275A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862628353P 2018-02-09 2018-02-09
PCT/US2019/017150 WO2019157245A1 (en) 2018-02-09 2019-02-08 Methods for treating mitochondrial disorders

Publications (1)

Publication Number Publication Date
MX2020008275A true MX2020008275A (es) 2020-11-24

Family

ID=67549579

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020008275A MX2020008275A (es) 2018-02-09 2019-02-08 Metodos para tratar trastornos mitocondriales.

Country Status (10)

Country Link
US (2) US12440461B2 (es)
EP (1) EP3559892A4 (es)
JP (3) JP7512206B2 (es)
CN (2) CN120919092A (es)
AU (1) AU2019217990B2 (es)
CA (1) CA3090394A1 (es)
MX (1) MX2020008275A (es)
PH (1) PH12020551179A1 (es)
SG (1) SG11202007286TA (es)
WO (1) WO2019157245A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113750082A (zh) * 2021-09-08 2021-12-07 北京化工大学 用于治疗前列腺炎及前列腺增生的药物及应用
CN114588141A (zh) * 2022-03-31 2022-06-07 北京化工大学 一种用于治疗银屑病的药物
CN116019795A (zh) * 2023-01-03 2023-04-28 北京化工大学 莱菔素用于制备抗衰老药物的用途
CN117017961A (zh) * 2023-08-14 2023-11-10 北京化工大学 一种莱菔素及其组合物在制备抗疲劳产品中的应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100500991B1 (ko) 2003-01-02 2005-07-14 육근우 황토 단무지의 제조방법
WO2006102236A1 (en) 2005-03-18 2006-09-28 Caudill Seed Inc. Cancer chemoprotective compositions and natural oils and methods for making same
WO2012142511A2 (en) 2011-04-15 2012-10-18 Md Matrix Health Llc Dba Md Matrix Health Inc Orthomolecular compositions and their use in stabilizing the extracellular matrix
EP2854862B1 (en) * 2012-06-01 2018-08-01 Pharmagra Labs, Inc. Sulforaphane isolation and purification
WO2015051492A1 (zh) * 2013-10-08 2015-04-16 北京化工大学 1-(烷基亚磺酰基)-2-异硫氰基烷基-1-烯烃在制备治疗多种癌症与肿瘤的药物中的应用
CN104510732A (zh) * 2013-10-08 2015-04-15 北京化工大学 1-(烷基亚磺酰基)-2-异硫氰基烷基-1-烯烃在制备治疗多种癌症与肿瘤的药物中的应用
CN104720072A (zh) * 2015-02-15 2015-06-24 北京化工大学 提高莱菔素稳定性的方法
CN106820118A (zh) * 2017-01-17 2017-06-13 吉速利（上海）健康科技股份有限公司 保健辅酶q10粉及其制备方法
CN106924213B (zh) * 2017-04-28 2020-04-07 领思科技(大连)有限公司 莱菔素微囊剂及其制备方法

Also Published As

Publication number Publication date
AU2019217990A1 (en) 2020-08-20
US12440461B2 (en) 2025-10-14
AU2019217990B2 (en) 2024-11-07
EP3559892A1 (en) 2019-10-30
JP2025071293A (ja) 2025-05-02
JP2023087054A (ja) 2023-06-22
PH12020551179A1 (en) 2021-06-07
US20190343784A1 (en) 2019-11-14
JP7512206B2 (ja) 2024-07-08
CN120919092A (zh) 2025-11-11
US20210330629A1 (en) 2021-10-28
EP3559892A4 (en) 2020-09-23
JP2021512961A (ja) 2021-05-20
WO2019157245A1 (en) 2019-08-15
CN110366739A (zh) 2019-10-22
NZ766695A (en) 2025-06-27
CA3090394A1 (en) 2019-08-15
SG11202007286TA (en) 2020-08-28
US11273135B2 (en) 2022-03-15

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