MX2020013000A - Composicion de hidrogel que comprende polimero reticulado. - Google Patents
Composicion de hidrogel que comprende polimero reticulado.Info
- Publication number
- MX2020013000A MX2020013000A MX2020013000A MX2020013000A MX2020013000A MX 2020013000 A MX2020013000 A MX 2020013000A MX 2020013000 A MX2020013000 A MX 2020013000A MX 2020013000 A MX2020013000 A MX 2020013000A MX 2020013000 A MX2020013000 A MX 2020013000A
- Authority
- MX
- Mexico
- Prior art keywords
- thiol
- hyaluronan
- hydrogel composition
- cross
- linked polymer
- Prior art date
Links
- 229920006037 cross link polymer Polymers 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000000017 hydrogel Substances 0.000 title abstract 2
- KIUKXJAPPMFGSW-MNSSHETKSA-N hyaluronan Chemical class CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)C1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H](C(O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-MNSSHETKSA-N 0.000 abstract 6
- 230000004048 modification Effects 0.000 abstract 3
- 238000012986 modification Methods 0.000 abstract 3
- 125000003396 thiol group Chemical group [H]S* 0.000 abstract 3
- 229940099552 hyaluronan Drugs 0.000 abstract 2
- 229920002674 hyaluronan Polymers 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/042—Gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/52—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/042—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/145—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/91—Injection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/23—Carbohydrates
- A61L2300/236—Glycosaminoglycans, e.g. heparin, hyaluronic acid, chondroitin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/402—Anaestetics, analgesics, e.g. lidocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/34—Materials or treatment for tissue regeneration for soft tissue reconstruction
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Birds (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Vascular Medicine (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Polymers & Plastics (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Cardiology (AREA)
- Gynecology & Obstetrics (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
Abstract
Una composición de hidrogel estéril que comprende un polímero reticulado, en donde el polímero reticulado es un producto de oxidación de un hialuronano modificado con tiol y en donde el hialuronano modificado con tiol tiene un grado de modificación de hialuronano con restos de tiol de más de aproximadamente 80 µmol por gramo de polímero, en donde el hialuronano modificado con tiol tiene un grado de modificación de hialuronano con restos de tiol de menos de aproximadamente 280 µmol por gramo de polímero, en donde la composición tiene un contenido de tiol residual de menos de 20% con respecto al grado de modificación del hialuronano modificado con tiol.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18178097 | 2018-06-15 | ||
| EP18178099 | 2018-06-15 | ||
| EP18178098 | 2018-06-15 | ||
| PCT/EP2019/065755 WO2019238954A1 (en) | 2018-06-15 | 2019-06-14 | Hydrogel composition comprising a crosslinked polymer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2020013000A true MX2020013000A (es) | 2021-03-29 |
Family
ID=66821271
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2020013000A MX2020013000A (es) | 2018-06-15 | 2019-06-14 | Composicion de hidrogel que comprende polimero reticulado. |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US12458582B2 (es) |
| EP (2) | EP3806918A1 (es) |
| JP (2) | JP2021526933A (es) |
| KR (2) | KR102852956B1 (es) |
| CN (3) | CN116650519A (es) |
| BR (2) | BR112020024735B1 (es) |
| CA (2) | CA3101410A1 (es) |
| ES (1) | ES2983810T3 (es) |
| IL (2) | IL279446B2 (es) |
| MA (2) | MA52877A (es) |
| MX (1) | MX2020013000A (es) |
| PL (1) | PL3806919T3 (es) |
| WO (2) | WO2019238954A1 (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2020013000A (es) | 2018-06-15 | 2021-03-29 | Croma Pharma Gmbh | Composicion de hidrogel que comprende polimero reticulado. |
| AR115549A1 (es) | 2018-06-15 | 2021-02-03 | Croma Pharma Gmbh | Composición de hidrogel que comprende un polímero reticulado |
| CN114787199B (zh) * | 2019-12-19 | 2023-06-20 | 克罗马药品有限责任公司 | 硫醇修饰的透明质酸和包含交联透明质酸的水凝胶 |
| WO2021143736A1 (en) * | 2020-01-16 | 2021-07-22 | The Hong Kong University Of Science And Technology | Compositions and methods for controlled release of target agent |
| CN115702937B (zh) * | 2021-08-04 | 2024-12-17 | 四川大学 | 改性多酚载体材料、靶向纳米递送系统及制备方法和用途 |
| KR20230145624A (ko) * | 2022-04-08 | 2023-10-18 | (주)아크로스 | 안전성이 우수한 조직수복용 생체재료의 제조 방법 |
| CN115414276A (zh) * | 2022-06-24 | 2022-12-02 | 辽宁德玛生物科技有限公司 | 一种注射用琼脂糖凝胶剂及其制备方法 |
| TWI840941B (zh) * | 2022-09-06 | 2024-05-01 | 科妍生物科技股份有限公司 | 製造自體交聯透明質酸凝膠之方法及其產物 |
| IT202200023682A1 (it) | 2022-11-16 | 2024-05-16 | Francesco Bernardini | Composizioni e metodi per migliorare difetti volumetrici del viso |
| WO2024113006A1 (en) * | 2022-11-28 | 2024-06-06 | Telethon Kids Institute | Novel hydrogels |
| CN117298355B (zh) * | 2023-11-28 | 2024-03-08 | 常州百瑞吉生物医药股份有限公司 | 一种包裹性透明质酸凝胶组合物及其制备方法与应用 |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4582865A (en) * | 1984-12-06 | 1986-04-15 | Biomatrix, Inc. | Cross-linked gels of hyaluronic acid and products containing such gels |
| US6174999B1 (en) | 1987-09-18 | 2001-01-16 | Genzyme Corporation | Water insoluble derivatives of polyanionic polysaccharides |
| US6630457B1 (en) | 1998-09-18 | 2003-10-07 | Orthogene Llc | Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same |
| AT406054B (de) | 1998-11-04 | 2000-02-25 | Andreas Bernkop-Schnuerch | Verfahren zur verbesserung der mucoadhäsion von polymeren sowie deren herstellung und verwendung |
| DE60133744T2 (de) | 2000-07-28 | 2009-05-14 | Anika Therapeutics, Inc., Woburn | Bioabsorbierbare kompositmaterialien aus derivatisierter hyaluronsäure |
| JP4176475B2 (ja) | 2001-01-19 | 2008-11-05 | 博徳 山本 | 内視鏡用注射剤 |
| ATE312076T1 (de) | 2001-02-22 | 2005-12-15 | Anika Therapeutics Inc | Thiol-modifizierte hyaluronan-derivate |
| GB2386900B (en) | 2002-03-25 | 2006-11-01 | Johnson & Johnson Medical Ltd | Use in wound dressings of chemically modified polysaccharides |
| ES2449017T3 (es) | 2002-06-21 | 2014-03-17 | The University Of Utah Research Foundation | Compuestos reticulados, y métodos de preparación y uso de los mismos |
| ZA200604869B (en) | 2003-12-04 | 2007-11-28 | Univ Utah Res Found | Modified macromolecules and methods of making and using thereof |
| KR101142583B1 (ko) | 2004-01-07 | 2012-05-11 | 세이가가쿠 고교 가부시키가이샤 | 히알루론산 유도체 및 그것을 포함하는 약제 |
| TW200536861A (en) | 2004-04-02 | 2005-11-16 | Denki Kagaku Kogyo Kk | Hyaluronic acid/methotrexate compound |
| US8143391B2 (en) | 2004-09-07 | 2012-03-27 | Chugai Seiyaku Kabushiki Kaisha | Process for producing water-soluble hyaluronic acid modification |
| ITPD20050242A1 (it) | 2005-08-03 | 2007-02-04 | Fidia Farmaceutici | Bioconiugati antitumorali dell'acido ialuronico o dei suoi derivati, ottenibili per coniugazione chimica diretta o indiretta, e loro impiego in campo farmaceutico |
| CN101287475B (zh) | 2005-09-07 | 2012-11-14 | 阿尔卡米亚肿瘤学股份有限公司 | 包含透明质酸和治疗抗体的治疗组合物以及制药用途 |
| US20080031854A1 (en) | 2006-07-11 | 2008-02-07 | Prestwich Glenn D | Thiolated macromolecules and methods of making and using thereof |
| FR2909560B1 (fr) * | 2006-12-06 | 2012-12-28 | Fabre Pierre Dermo Cosmetique | Gel d'acide hyaluronique pour injection intradermique |
| CN101200504B (zh) | 2006-12-11 | 2010-05-12 | 上海百瑞吉生物医药有限公司 | 高分子巯基化改性衍生物及其交联材料 |
| US9597277B2 (en) * | 2006-12-22 | 2017-03-21 | Croma-Pharma Gesellschaft M.B.H. | Use of polymers |
| CA2686505A1 (fr) * | 2007-05-11 | 2008-11-20 | Galderma Research & Development | Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations |
| WO2008148071A2 (en) | 2007-05-24 | 2008-12-04 | Nidus2, Llc | Injectable dermis |
| WO2009005790A2 (en) * | 2007-06-29 | 2009-01-08 | Carbylan Biosurgery, Inc. | Sterile thiol-derivatized hyaluronic acid polymer compositions and uses thereof |
| CA2694089A1 (en) * | 2007-07-16 | 2009-01-22 | Northeastern University | Therapeutic stable nanoparticles |
| US9161970B2 (en) * | 2007-12-12 | 2015-10-20 | Allergan, Inc. | Dermal filler |
| WO2009105614A2 (en) | 2008-02-22 | 2009-08-27 | Dermal Technologies, Llc | Compositions for tissue augmentation |
| US9585987B2 (en) | 2008-02-29 | 2017-03-07 | Pvac Medical Technologies Ltd | Composition for the formation of gels |
| US20090269417A1 (en) | 2008-04-24 | 2009-10-29 | Medtronic, Inc. | Thiolated chitosan gel |
| CN101367884A (zh) | 2008-09-25 | 2009-02-18 | 复旦大学 | 一种半胱胺修饰的巯基化透明质酸偶合物及其制备方法和应用 |
| CN101721349B (zh) | 2008-10-16 | 2011-07-20 | 常州百瑞吉生物医药有限公司 | 可注射原位交联水凝胶及其制备方法和用途 |
| EP2411064A2 (en) | 2009-03-23 | 2012-02-01 | Genzyme Corporation | Cartilage repair |
| US20110172180A1 (en) | 2010-01-13 | 2011-07-14 | Allergan Industrie. Sas | Heat stable hyaluronic acid compositions for dermatological use |
| CN102399295B (zh) * | 2010-09-09 | 2013-11-06 | 常州百瑞吉生物医药有限公司 | 低巯基化改性度生物相容高分子巯基化衍生物及其交联材料和用途 |
| US9393263B2 (en) * | 2011-06-03 | 2016-07-19 | Allergan, Inc. | Dermal filler compositions including antioxidants |
| KR102312056B1 (ko) | 2011-06-03 | 2021-10-12 | 알러간 인더스트리 에스에이에스 | 항산화제를 포함하는 피부 충전제 조성물 |
| WO2013040242A2 (en) * | 2011-09-14 | 2013-03-21 | Allergan, Inc. | Dermal filler compositions for fine line treatment |
| ES2823650T3 (es) * | 2011-12-08 | 2021-05-07 | Allergan Ind Sas | Composiciones de relleno dérmico |
| FR2997014B1 (fr) | 2012-10-24 | 2015-03-20 | Teoxane | Composition sterile dermo-injectable |
| ES2661913T3 (es) | 2013-05-08 | 2018-04-04 | Allergan Industrie | Geles de ácido hialurónico reticulados con trimetafosfato de sodio |
| JP6434003B2 (ja) | 2013-06-28 | 2018-12-05 | ガルデルマ エス．エー． | 成形された架橋ヒアルロン酸生成物を製造するための方法 |
| ITMI20131193A1 (it) * | 2013-07-16 | 2015-01-17 | Ira Srl | Acido ialuronico reticolato, processo per la sua preparazione ed applicazioni in ambito estetico |
| ES2725430T3 (es) | 2014-07-11 | 2019-09-24 | Allergan Ind Sas | Geles de ácido hialurónico reticulados por trimetafosfato de sodio |
| CN104892962B (zh) | 2015-06-05 | 2017-12-08 | 四川大学 | 一种巯基/二硫键可控自交联透明质酸水凝胶的制备方法及其应用 |
| IT201600096125A1 (it) * | 2016-09-26 | 2018-03-26 | Ntc Srl | Complesso e composizioni per il trattamento di affezioni oculari e cutanee |
| AR110125A1 (es) | 2016-11-07 | 2019-02-27 | Croma Pharma Ges M B H | Compuestos poliméricos que liberan sulfuro de hidrógeno |
| CN108465128B (zh) | 2018-03-01 | 2021-03-16 | 杭州协合医疗用品有限公司 | 一种交联透明质酸细胞支架材料的制备方法 |
| MX2020013000A (es) | 2018-06-15 | 2021-03-29 | Croma Pharma Gmbh | Composicion de hidrogel que comprende polimero reticulado. |
-
2019
- 2019-06-14 MX MX2020013000A patent/MX2020013000A/es unknown
- 2019-06-14 US US17/252,549 patent/US12458582B2/en active Active
- 2019-06-14 CN CN202310704045.6A patent/CN116650519A/zh active Pending
- 2019-06-14 WO PCT/EP2019/065755 patent/WO2019238954A1/en not_active Ceased
- 2019-06-14 CN CN201980038268.5A patent/CN112334165A/zh active Pending
- 2019-06-14 IL IL279446A patent/IL279446B2/en unknown
- 2019-06-14 CA CA3101410A patent/CA3101410A1/en active Pending
- 2019-06-14 US US17/252,532 patent/US12097277B2/en active Active
- 2019-06-14 JP JP2020569872A patent/JP2021526933A/ja active Pending
- 2019-06-14 PL PL19731275.4T patent/PL3806919T3/pl unknown
- 2019-06-14 EP EP19729775.7A patent/EP3806918A1/en active Pending
- 2019-06-14 KR KR1020217000861A patent/KR102852956B1/ko active Active
- 2019-06-14 CN CN201980040062.6A patent/CN112334167A/zh active Pending
- 2019-06-14 JP JP2020569875A patent/JP7374133B2/ja active Active
- 2019-06-14 ES ES19731275T patent/ES2983810T3/es active Active
- 2019-06-14 BR BR112020024735-9A patent/BR112020024735B1/pt active IP Right Grant
- 2019-06-14 EP EP19731275.4A patent/EP3806919B1/en active Active
- 2019-06-14 WO PCT/EP2019/065756 patent/WO2019238955A1/en not_active Ceased
- 2019-06-14 IL IL279445A patent/IL279445B2/en unknown
- 2019-06-14 BR BR112020024637-9A patent/BR112020024637B1/pt active IP Right Grant
- 2019-06-14 MA MA052877A patent/MA52877A/fr unknown
- 2019-06-14 CA CA3101412A patent/CA3101412A1/en active Pending
- 2019-06-14 MA MA052880A patent/MA52880A/fr unknown
- 2019-06-14 KR KR1020217000860A patent/KR20210021362A/ko not_active Ceased
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2020013000A (es) | Composicion de hidrogel que comprende polimero reticulado. | |
| CY1122122T1 (el) | Υδατικο οφθαλμικο διαλυμα και μεθοδος για τη θεραπευτικη αγωγη συνδρομου ξηρου οφθαλμου | |
| CL2012003684A1 (es) | Una solucion oftalmica que incluye por lo menos una prostaglandina, un agente solubilizador, un agente gelificador carbomero, un agente inhibidor de la polimerizacion del carbomero y un agente co-gelificador/co-solubilizador, la cual tiene una viscosidad entre 8 y 20 mpa.s y no contiene conservadores antimicrobianos; y frasco que la comprende. | |
| MX2015002448A (es) | Lentes de contacto fabricados con macromeros de polisiloxano compatibles con hema. | |
| AR117592A1 (es) | Composición de hidrogel que comprende un polímero reticulado | |
| EA201690712A1 (ru) | Композиции из фрагментов белков шелка и изделия, изготовленные из них | |
| AR081020A1 (es) | Polimeros hidrofilos no reactivos que tienen siloxanos terminales y metodos para prepararlos y usarlos | |
| BR112015022755A2 (pt) | métodos para a reticulação de composições de polímeros na presença de oxigênio atmosférico | |
| MX394705B (es) | Desinfectante de superficies con propiedad biocida residual | |
| MX341475B (es) | Composiciones de copolimero hibrido para aplicaciones de cuidado personal. | |
| BR112017012184A2 (pt) | composições e métodos para reticular polímeros na presença de oxigênio atmosférico | |
| EP4233926A3 (en) | Methods of manufacturing injectable gels comprising cross-linked hyaluronic acid and hydroxyapatite | |
| ECSP21026021A (es) | Moduladores de la expresión de pnpla3 | |
| BR112016029341A2 (pt) | composições poliméricas curáveis por umidade tendo polímeros halogenados e mercaptidas de metal | |
| MX2020003947A (es) | Anticuerpo anti-cd3 y composicion farmaceutica para el tratamiento del cancer que comprende el mismo. | |
| MX2020003943A (es) | Anticuerpo anti-msln y composicion farmaceutica para el tratamiento del cancer que comprende el mismo. | |
| EP4378535A3 (en) | Antibiotic formulations for lower back pain | |
| EP4368208A3 (en) | Novel hyaluronic acid-based hydrogels having medical applications | |
| AR098764A1 (es) | Composición de polímero vulcanizable | |
| CO2019008987A2 (es) | Mejoras en o con respecto a compuestos orgánicos | |
| CL2016002572A1 (es) | Artículo moldeado por soplado por inyección y estiramiento que comprende una resina de hdpe que tiene un mi2 de 0,5-8,0 dg/min, una polidispersidad (mw/mn) de 2,0-7,0, una viscosidad de cizallamiento cero entre 1.000-50.000 pa•sec, además tiene 45° de brillo de más de o igual a 50 y una turbidez de menos de 0 igual a 25%. | |
| MX390139B (es) | Caucho de copolimero que contiene grupo nitrilo, composicion de caucho reticulable, y caucho reticulado | |
| MX2019003206A (es) | Gel de acido hialuronico con un cation de zinc divalente. | |
| BR112017022737A2 (pt) | adesivo funcionalizado, halogenado à base de olefina, artigos que contendo o mesmo, e processo para usar o mesmo | |
| MX2019007216A (es) | Caucho de nitrilo que contiene grupo carboxilo, metodo para producir el mismo, composicion de caucho de nitrilo reticulable, y caucho reticulado. |