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MX2019014960A - Composiciones de fosfodiesterasa de tipo 5 (pde5) y métodos de inmunoterapia. - Google Patents

Composiciones de fosfodiesterasa de tipo 5 (pde5) y métodos de inmunoterapia.

Info

Publication number
MX2019014960A
MX2019014960A MX2019014960A MX2019014960A MX2019014960A MX 2019014960 A MX2019014960 A MX 2019014960A MX 2019014960 A MX2019014960 A MX 2019014960A MX 2019014960 A MX2019014960 A MX 2019014960A MX 2019014960 A MX2019014960 A MX 2019014960A
Authority
MX
Mexico
Prior art keywords
methods
compositions
pde5
immunotherapy
proteins
Prior art date
Application number
MX2019014960A
Other languages
English (en)
Inventor
Celeste Richardson
Vipin Suri
Brian Dolinski
Scott Francis Heller
Abhishek Kulkarni
Mara Christine Inniss
dan jun Li
Dexue Sun
Byron Delabarre
Michael N Gladstone
Grace Y Olinger
Original Assignee
Obsidian Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Obsidian Therapeutics Inc filed Critical Obsidian Therapeutics Inc
Publication of MX2019014960A publication Critical patent/MX2019014960A/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • C07K14/52—Cytokines; Lymphokines; Interferons
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    • C—CHEMISTRY; METALLURGY
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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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  • Medicinal Chemistry (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Endocrinology (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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Abstract

La presente invención hace referencia a composiciones y métodos para expresión controlada y regulada de proteínas. También se proporcionan métodos para inducir respuestas inmunitarias contra el cáncer en un sujeto.
MX2019014960A 2017-06-12 2018-06-12 Composiciones de fosfodiesterasa de tipo 5 (pde5) y métodos de inmunoterapia. MX2019014960A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762518078P 2017-06-12 2017-06-12
US201762523862P 2017-06-23 2017-06-23
US201762523850P 2017-06-23 2017-06-23
US201762555313P 2017-09-07 2017-09-07
PCT/US2018/037005 WO2018231759A1 (en) 2017-06-12 2018-06-12 Pde5 compositions and methods for immunotherapy

Publications (1)

Publication Number Publication Date
MX2019014960A true MX2019014960A (es) 2020-08-06

Family

ID=64660633

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019014960A MX2019014960A (es) 2017-06-12 2018-06-12 Composiciones de fosfodiesterasa de tipo 5 (pde5) y métodos de inmunoterapia.

Country Status (9)

Country Link
US (2) US11241485B2 (es)
EP (1) EP3638289A4 (es)
JP (2) JP7362596B2 (es)
CN (1) CN111107866A (es)
CA (1) CA3067211A1 (es)
MA (1) MA49403A (es)
MX (1) MX2019014960A (es)
SG (1) SG11201912010XA (es)
WO (1) WO2018231759A1 (es)

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