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MX2019014008A - Composiciones y usos para inmunoterapia. - Google Patents

Composiciones y usos para inmunoterapia.

Info

Publication number
MX2019014008A
MX2019014008A MX2019014008A MX2019014008A MX2019014008A MX 2019014008 A MX2019014008 A MX 2019014008A MX 2019014008 A MX2019014008 A MX 2019014008A MX 2019014008 A MX2019014008 A MX 2019014008A MX 2019014008 A MX2019014008 A MX 2019014008A
Authority
MX
Mexico
Prior art keywords
cells
methods
immunosensitive
immunotherapy
compositions
Prior art date
Application number
MX2019014008A
Other languages
English (en)
Inventor
Sadelain Michel
D Fedorov Victor
Original Assignee
Memorial Sloan Kettering Cancer Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Memorial Sloan Kettering Cancer Center filed Critical Memorial Sloan Kettering Cancer Center
Publication of MX2019014008A publication Critical patent/MX2019014008A/es

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
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Abstract

La presente invención proporciona células inmunosensibles, incluyendo células T, células T citotóxicas, células T reguladoras, y células Asesinas Naturales (NK), que expresan un receptor de reconocimiento de antígeno y un receptor de antígeno quimérico inhibidor (iCAR); métodos para utilizar la célula inmunosensible incluyen aquellos para el tratamiento de neoplasia y otras patologías donde se desea un aumento en una respuesta inmune específica de antígeno.
MX2019014008A 2013-03-15 2015-09-15 Composiciones y usos para inmunoterapia. MX2019014008A (es)

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