MX2019012952A - Composiciones parasiticidas que comprenden derivados de indol, metodos y usos de los mismos. - Google Patents
Composiciones parasiticidas que comprenden derivados de indol, metodos y usos de los mismos.Info
- Publication number
- MX2019012952A MX2019012952A MX2019012952A MX2019012952A MX2019012952A MX 2019012952 A MX2019012952 A MX 2019012952A MX 2019012952 A MX2019012952 A MX 2019012952A MX 2019012952 A MX2019012952 A MX 2019012952A MX 2019012952 A MX2019012952 A MX 2019012952A
- Authority
- MX
- Mexico
- Prior art keywords
- indeol
- derivatives
- methods
- compositions including
- parasiticide compositions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000000590 parasiticidal effect Effects 0.000 title 1
- 239000002297 parasiticide Substances 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 3
- 241000242594 Platyhelminthes Species 0.000 abstract 2
- 210000004185 liver Anatomy 0.000 abstract 2
- 244000045947 parasite Species 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- 150000002475 indoles Chemical class 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 239000007972 injectable composition Substances 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/36—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings
- A01N43/38—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03K—PULSE TECHNIQUE
- H03K5/00—Manipulating of pulses not covered by one of the other main groups of this subclass
- H03K5/01—Shaping pulses
- H03K5/04—Shaping pulses by increasing duration; by decreasing duration
-
- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03K—PULSE TECHNIQUE
- H03K7/00—Modulating pulses with a continuously-variable modulating signal
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Pest Control & Pesticides (AREA)
- Dentistry (AREA)
- Environmental Sciences (AREA)
- Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- Agronomy & Crop Science (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nonlinear Science (AREA)
- Physics & Mathematics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
La invención se relaciona a composiciones orales, tópicas o inyectables para combatir parásitos de gusanos planos del hígado en mamíferos, que comprenden por lo menos un agente activo de derivado de indol. La invención también proporciona un método mejorado para erradicar y controlar las infecciones e infestaciones de parásitos de gusanos planos del hígado en un mamífero que comprende administrar las composiciones de la invención al mamífero en necesidad de las mismas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462014245P | 2014-06-19 | 2014-06-19 | |
| PCT/US2015/036580 WO2015196014A1 (en) | 2014-06-19 | 2015-06-19 | Parasiticidal compositions comprising indole derivatives, methods and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2019012952A true MX2019012952A (es) | 2019-12-16 |
| MX383300B MX383300B (es) | 2025-03-13 |
Family
ID=54868421
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019012952A MX383300B (es) | 2014-06-19 | 2015-06-19 | Composiciones parasiticidas que comprenden derivados de indol, metodos y usos de los mismos. |
| MX2016016928A MX2016016928A (es) | 2014-06-19 | 2015-06-19 | Composiciones parasiticidas que comprenden derivados de indol, metodos y usos de los mismos. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016016928A MX2016016928A (es) | 2014-06-19 | 2015-06-19 | Composiciones parasiticidas que comprenden derivados de indol, metodos y usos de los mismos. |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US9776986B2 (es) |
| EP (2) | EP3157912B1 (es) |
| JP (1) | JP6619756B2 (es) |
| CN (1) | CN106536481B (es) |
| AU (2) | AU2015276941B2 (es) |
| BR (2) | BR112016029888B1 (es) |
| CA (1) | CA2952857A1 (es) |
| CL (3) | CL2016003258A1 (es) |
| CO (1) | CO2017000412A2 (es) |
| EA (1) | EA030459B1 (es) |
| ES (2) | ES2723969T3 (es) |
| MX (2) | MX383300B (es) |
| NZ (1) | NZ728102A (es) |
| PT (1) | PT3157912T (es) |
| WO (1) | WO2015196014A1 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3307706B1 (en) * | 2015-06-15 | 2019-07-24 | Bayer CropScience AG | Halogen-substituted phenoxyphenylamidines and the use thereof as fungicides |
| CN107082758A (zh) * | 2016-02-15 | 2017-08-22 | 中山大学 | 一种合成吲哚衍生物的方法 |
| US10426772B2 (en) | 2016-05-16 | 2019-10-01 | Regents Of The University Of Minnesota | Use of ergot alkaloids as an anthelmintic agent |
| KR102204380B1 (ko) * | 2019-04-03 | 2021-01-19 | 영남대학교산학협력단 | 5-브로모인돌을 유효성분으로 함유하는 소나무재선충병 방제용 조성물 및 이의 용도 |
| CN112675850A (zh) * | 2020-12-23 | 2021-04-20 | 江苏广域化学有限公司 | 镍催化剂、其制备方法及嘧啶类衍生物的合成方法 |
| CN113109332A (zh) * | 2021-04-14 | 2021-07-13 | 山东商业职业技术学院 | 食盐中碘酸钾的快速检测试剂及方法 |
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| KR101022649B1 (ko) * | 2008-08-07 | 2011-03-22 | 삼성모바일디스플레이주식회사 | 헤테로고리 화합물 및 이를 이용한 유기 전계 발광 장치 |
| AU2009309027A1 (en) | 2008-10-31 | 2010-05-06 | Merck Sharp & Dohme Corp. | Novel substituted azabenzoxazoles |
| CN102070618B (zh) * | 2009-11-23 | 2013-08-21 | 和记黄埔医药(上海)有限公司 | 一种化合物及其晶体 |
| CN102153544B (zh) * | 2010-02-12 | 2015-04-29 | 上海阳帆医药科技有限公司 | 一类酪氨酸激酶抑制剂的制备及用途 |
| EP2455378A1 (en) | 2010-11-03 | 2012-05-23 | Philip Morris Products S.A. | Carbazole and carboline derivatives, and preparation and therapeutic applications thereof |
| AR084433A1 (es) * | 2010-12-22 | 2013-05-15 | Ironwood Pharmaceuticals Inc | Inhibidores de la faah y composiciones farmaceuticas que los contienen |
| WO2012088431A1 (en) * | 2010-12-23 | 2012-06-28 | Ironwood Pharmaceuticals, Inc. | Faah inhibitors |
| EP2669271A4 (en) * | 2011-01-25 | 2014-08-13 | Kissei Pharmaceutical | INDOLE DERIVATIVE AND PHARMACEUTICAL ACCEPTABLE SALT THEREOF |
| EP2685824A4 (en) | 2011-03-17 | 2014-09-10 | Merck Sharp & Dohme | INDUSTRIAL DERIVATIVES USED AS CCR2 ANTAGONISTS |
| SG11201406730RA (en) * | 2012-04-20 | 2014-11-27 | Merial Ltd | Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof |
| CN103641767B (zh) * | 2013-11-22 | 2017-01-11 | 沈阳药科大学 | 取代苯基吲哚基硒醚、硒亚砜、硒砜及其作为肿瘤细胞增殖抑制剂的用途 |
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2015
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- 2015-06-19 CN CN201580040216.3A patent/CN106536481B/zh active Active
- 2015-06-19 BR BR112016029888-8A patent/BR112016029888B1/pt not_active IP Right Cessation
- 2015-06-19 PT PT15738519T patent/PT3157912T/pt unknown
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- 2015-06-19 MX MX2019012952A patent/MX383300B/es unknown
- 2015-06-19 CA CA2952857A patent/CA2952857A1/en not_active Abandoned
- 2015-06-19 ES ES18212461T patent/ES2895826T3/es active Active
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- 2015-06-19 MX MX2016016928A patent/MX2016016928A/es active IP Right Grant
- 2015-06-19 AU AU2015276941A patent/AU2015276941B2/en active Active
- 2015-06-19 EP EP15738519.6A patent/EP3157912B1/en active Active
- 2015-06-19 JP JP2016574080A patent/JP6619756B2/ja not_active Expired - Fee Related
- 2015-06-19 NZ NZ728102A patent/NZ728102A/en unknown
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- 2015-06-19 EP EP18212461.0A patent/EP3517524B1/en active Active
- 2015-06-19 WO PCT/US2015/036580 patent/WO2015196014A1/en not_active Ceased
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2016
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2017
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2018
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2019
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Also Published As
| Publication number | Publication date |
|---|---|
| US20170290803A1 (en) | 2017-10-12 |
| PT3157912T (pt) | 2019-06-04 |
| WO2015196014A1 (en) | 2015-12-23 |
| CL2019000462A1 (es) | 2019-05-10 |
| BR112016029888A2 (pt) | 2017-08-22 |
| JP6619756B2 (ja) | 2019-12-11 |
| CL2016003258A1 (es) | 2017-06-16 |
| MX2016016928A (es) | 2017-04-25 |
| EP3517524A1 (en) | 2019-07-31 |
| CL2020002588A1 (es) | 2021-01-22 |
| EA201790040A1 (ru) | 2017-05-31 |
| ES2895826T3 (es) | 2022-02-22 |
| JP2017518352A (ja) | 2017-07-06 |
| CO2017000412A2 (es) | 2017-04-28 |
| US9776986B2 (en) | 2017-10-03 |
| ES2723969T3 (es) | 2019-09-04 |
| AU2015276941B2 (en) | 2018-07-19 |
| EP3157912A1 (en) | 2017-04-26 |
| CN106536481B (zh) | 2019-11-22 |
| BR112016029888B1 (pt) | 2021-05-18 |
| MX383300B (es) | 2025-03-13 |
| US10251863B2 (en) | 2019-04-09 |
| EP3157912B1 (en) | 2019-02-20 |
| EA030459B1 (ru) | 2018-08-31 |
| US20150366198A1 (en) | 2015-12-24 |
| AU2015276941A1 (en) | 2017-02-02 |
| CN106536481A (zh) | 2017-03-22 |
| EP3517524B1 (en) | 2021-05-26 |
| BR122020023385B1 (pt) | 2021-05-25 |
| AU2018205140A1 (en) | 2018-08-02 |
| NZ728102A (en) | 2018-04-27 |
| CA2952857A1 (en) | 2015-12-23 |
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