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MX2019011897A - Celulas efectoras inmunitarias especificas de antigenos. - Google Patents

Celulas efectoras inmunitarias especificas de antigenos.

Info

Publication number
MX2019011897A
MX2019011897A MX2019011897A MX2019011897A MX2019011897A MX 2019011897 A MX2019011897 A MX 2019011897A MX 2019011897 A MX2019011897 A MX 2019011897A MX 2019011897 A MX2019011897 A MX 2019011897A MX 2019011897 A MX2019011897 A MX 2019011897A
Authority
MX
Mexico
Prior art keywords
antigen
effector cells
immune effector
specific immune
lymphocytes
Prior art date
Application number
MX2019011897A
Other languages
English (en)
Inventor
A Vodyanyk Maksym
Zhang Xin
j brandl Andrew
Rajesh Deepika
Swanson Bradley
Munn Christie
Burton Sarah
Bo Wang Wen
MCLEOD Ethan
Original Assignee
Fujifilm Cellular Dynamics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujifilm Cellular Dynamics Inc filed Critical Fujifilm Cellular Dynamics Inc
Publication of MX2019011897A publication Critical patent/MX2019011897A/es

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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/15—Natural-killer [NK] cells; Natural-killer T [NKT] cells
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    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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Abstract

En la presente se proporcionan métodos para la producción de linfocitos NK y linfocitos T efectores específicos de antígenos a partir de células madre pluripotentes que expresan un receptor de antígenos quiméricos (CAR). Además, en la presente se proporcionan métodos para la terapia celular adoptiva mediante la administración de los linfocitos NK y/o linfocitos T efectores que se proporcionan en la presente.
MX2019011897A 2017-04-18 2018-04-18 Celulas efectoras inmunitarias especificas de antigenos. MX2019011897A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762486875P 2017-04-18 2017-04-18
PCT/US2018/028133 WO2018195175A1 (en) 2017-04-18 2018-04-18 Antigen-specific immune effector cells

Publications (1)

Publication Number Publication Date
MX2019011897A true MX2019011897A (es) 2019-11-28

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Application Number Title Priority Date Filing Date
MX2019011897A MX2019011897A (es) 2017-04-18 2018-04-18 Celulas efectoras inmunitarias especificas de antigenos.

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Country Link
US (1) US12163155B2 (es)
EP (2) EP3612557B1 (es)
JP (1) JP7181219B2 (es)
KR (1) KR102668891B1 (es)
CN (1) CN110891967B (es)
AU (1) AU2018254442B2 (es)
BR (1) BR112019021745A2 (es)
CA (1) CA3058779A1 (es)
DK (1) DK3612557T3 (es)
EA (1) EA201992469A1 (es)
ES (1) ES2912383T3 (es)
IL (1) IL269716B2 (es)
MX (1) MX2019011897A (es)
SG (1) SG11201909331UA (es)
WO (1) WO2018195175A1 (es)

Families Citing this family (26)

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WO2018195175A1 (en) 2018-10-25
CN110891967A (zh) 2020-03-17
CN110891967B (zh) 2025-03-14
US12163155B2 (en) 2024-12-10
CA3058779A1 (en) 2018-10-25
EA201992469A1 (ru) 2020-05-27
IL269716B2 (en) 2025-07-01
KR20190141190A (ko) 2019-12-23
EP3612557A1 (en) 2020-02-26
EP4083063A2 (en) 2022-11-02
DK3612557T3 (da) 2022-04-19
AU2018254442A1 (en) 2019-10-17
AU2018254442B2 (en) 2024-03-28
BR112019021745A2 (pt) 2020-05-05
EP3612557B1 (en) 2022-01-19

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