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MX2019011570A - Lineas celulares estimuladoras para expansion y activacion ex vivo de celulas asesinas naturales. - Google Patents

Lineas celulares estimuladoras para expansion y activacion ex vivo de celulas asesinas naturales.

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Publication number
MX2019011570A
MX2019011570A MX2019011570A MX2019011570A MX2019011570A MX 2019011570 A MX2019011570 A MX 2019011570A MX 2019011570 A MX2019011570 A MX 2019011570A MX 2019011570 A MX2019011570 A MX 2019011570A MX 2019011570 A MX2019011570 A MX 2019011570A
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MX
Mexico
Prior art keywords
cell lines
natural killer
cells
activation
killer cells
Prior art date
Application number
MX2019011570A
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English (en)
Inventor
Campana Dario
Kamiya Takahiro
Original Assignee
Nat Univ Singapore
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Publication date
Application filed by Nat Univ Singapore filed Critical Nat Univ Singapore
Publication of MX2019011570A publication Critical patent/MX2019011570A/es

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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0646—Natural killers cells [NK], NKT cells
    • A—HUMAN NECESSITIES
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    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/15—Natural-killer [NK] cells; Natural-killer T [NKT] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/00—Cellular immunotherapy
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    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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  • Health & Medical Sciences (AREA)
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  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Varias modalidades descritas en el presente documento se refieren a lineas celulares estimuladoras disenadas para expandir preferentemente celulas asesinas naturales (NK) en un cultivo celular mixto que comprende celulas NK y celulas T. En varias modalidades, tambien se proporcionan poblaciones de celulas NK derivadas del cultivo conjunto de un cultivo celular mixto con lineas celulares estimuladoras. Los usos de las lineas celulares estimuladoras para expandir preferentemente las celulas NK en un cultivo celular mixto tambien se proporcionan en varias modalidades.
MX2019011570A 2017-03-27 2018-03-27 Lineas celulares estimuladoras para expansion y activacion ex vivo de celulas asesinas naturales. MX2019011570A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762477311P 2017-03-27 2017-03-27
PCT/SG2018/050138 WO2018182511A1 (en) 2017-03-27 2018-03-27 Stimulatory cell lines for ex vivo expansion and activation of natural killer cells

Publications (1)

Publication Number Publication Date
MX2019011570A true MX2019011570A (es) 2019-11-18

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MX2019011570A MX2019011570A (es) 2017-03-27 2018-03-27 Lineas celulares estimuladoras para expansion y activacion ex vivo de celulas asesinas naturales.

Country Status (13)

Country Link
US (1) US11896616B2 (es)
EP (1) EP3601537A4 (es)
JP (1) JP7270253B2 (es)
KR (1) KR102624509B1 (es)
CN (1) CN110494557A (es)
AU (1) AU2018245749A1 (es)
BR (1) BR112019020001A2 (es)
CA (1) CA3056591A1 (es)
IL (1) IL269380A (es)
MX (1) MX2019011570A (es)
RU (1) RU2019128544A (es)
SG (1) SG11201908337VA (es)
WO (1) WO2018182511A1 (es)

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