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MX2019009552A - Terapias de combinacion para el tratamiento de canceres relacionados con el antigeno de maduracion de celulas b (bcma) y trastornos autoinmunitarios. - Google Patents

Terapias de combinacion para el tratamiento de canceres relacionados con el antigeno de maduracion de celulas b (bcma) y trastornos autoinmunitarios.

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Publication number
MX2019009552A
MX2019009552A MX2019009552A MX2019009552A MX2019009552A MX 2019009552 A MX2019009552 A MX 2019009552A MX 2019009552 A MX2019009552 A MX 2019009552A MX 2019009552 A MX2019009552 A MX 2019009552A MX 2019009552 A MX2019009552 A MX 2019009552A
Authority
MX
Mexico
Prior art keywords
bcma
treatment
cell antigen
combination therapies
autoimmune disorders
Prior art date
Application number
MX2019009552A
Other languages
English (en)
Inventor
R Riddell Stanley
GREEN Damian
HILL Tyler
Original Assignee
Hutchinson Fred Cancer Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hutchinson Fred Cancer Res filed Critical Hutchinson Fred Cancer Res
Publication of MX2019009552A publication Critical patent/MX2019009552A/es

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    • A61K39/001102—Receptors, cell surface antigens or cell surface determinants
    • A61K39/001116—Receptors for cytokines
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Abstract

La presente invención se refiere a métodos para usar moléculas de unión específicas de BCMA (tales como un receptor o anticuerpo de antígeno quimérico específico de BCMA) en combinación con inhibidores de ?-secretasa, que se pueden hacer de manera concurrente o secuencial, para tratar o prevenir una enfermedad proliferativa relacionada con células B, tal como un cáncer o una enfermedad autoinmunitaria, o similares. Se puede usar una molécula de unión específica de BCMA en combinación con un inhibidor de ?-secretasa por ejemplo, en inmunoterapia adoptiva.
MX2019009552A 2017-02-17 2018-02-16 Terapias de combinacion para el tratamiento de canceres relacionados con el antigeno de maduracion de celulas b (bcma) y trastornos autoinmunitarios. MX2019009552A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762460612P 2017-02-17 2017-02-17
US201762582270P 2017-11-06 2017-11-06
PCT/US2018/000050 WO2018151836A1 (en) 2017-02-17 2018-02-16 Combination therapies for treatment of bcma-related cancers and autoimmune disorders

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MX2019009552A true MX2019009552A (es) 2019-10-02

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MX2019009552A MX2019009552A (es) 2017-02-17 2018-02-16 Terapias de combinacion para el tratamiento de canceres relacionados con el antigeno de maduracion de celulas b (bcma) y trastornos autoinmunitarios.

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US (2) US11845803B2 (es)
EP (2) EP4269594A3 (es)
JP (3) JP2020507605A (es)
KR (2) KR20240063204A (es)
CN (2) CN117357638A (es)
AU (2) AU2018222749B2 (es)
BR (1) BR112019017120A8 (es)
CA (1) CA3052779A1 (es)
ES (1) ES2949364T3 (es)
IL (1) IL268349B2 (es)
MX (1) MX2019009552A (es)
PH (1) PH12019550153A1 (es)
SG (1) SG11201907580SA (es)
WO (1) WO2018151836A1 (es)

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