[go: up one dir, main page]

MX2019009362A - Compuestos heterociclicos novedosos y sus usos en la prevencion o el tratamiento de infecciones bacterianas. - Google Patents

Compuestos heterociclicos novedosos y sus usos en la prevencion o el tratamiento de infecciones bacterianas.

Info

Publication number
MX2019009362A
MX2019009362A MX2019009362A MX2019009362A MX2019009362A MX 2019009362 A MX2019009362 A MX 2019009362A MX 2019009362 A MX2019009362 A MX 2019009362A MX 2019009362 A MX2019009362 A MX 2019009362A MX 2019009362 A MX2019009362 A MX 2019009362A
Authority
MX
Mexico
Prior art keywords
preventing
bacterial infections
treating bacterial
heterocyclic compounds
novel heterocyclic
Prior art date
Application number
MX2019009362A
Other languages
English (en)
Inventor
Le Strat Frédéric
Chasset Sophie
Chevreuil Francis
Barbion Julien
Caravano Audrey
Simon Christophe
Ledoussal Benoît
Oliveira Chrystelle
Waeckel Ludovic
Hélène QUERNIN Marie-
Moreau François
Original Assignee
Mutabilis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mutabilis filed Critical Mutabilis
Publication of MX2019009362A publication Critical patent/MX2019009362A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se refiere a compuesto de fórmula (I) y sus usos para el tratamiento de infecciones bacterianas. (ver Fórmula).
MX2019009362A 2017-02-06 2018-02-06 Compuestos heterociclicos novedosos y sus usos en la prevencion o el tratamiento de infecciones bacterianas. MX2019009362A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17305127 2017-02-06
EP17305958 2017-07-18
PCT/EP2018/052963 WO2018141991A1 (en) 2017-02-06 2018-02-06 Novel heterocyclic compounds and their use in preventing or treating bacterial infections

Publications (1)

Publication Number Publication Date
MX2019009362A true MX2019009362A (es) 2019-10-22

Family

ID=61168117

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019009362A MX2019009362A (es) 2017-02-06 2018-02-06 Compuestos heterociclicos novedosos y sus usos en la prevencion o el tratamiento de infecciones bacterianas.

Country Status (15)

Country Link
US (1) US20200017496A1 (es)
EP (1) EP3577117A1 (es)
JP (1) JP2020506198A (es)
KR (1) KR20190115062A (es)
CN (1) CN110392684A (es)
AU (1) AU2018216243A1 (es)
BR (1) BR112019015834A2 (es)
CA (1) CA3051972A1 (es)
CL (1) CL2019002203A1 (es)
IL (1) IL268362A (es)
MX (1) MX2019009362A (es)
RU (1) RU2019124705A (es)
TW (1) TW201831482A (es)
WO (1) WO2018141991A1 (es)
ZA (1) ZA201904998B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3110111A1 (en) 2018-08-09 2020-02-13 Antabio Sas Diazabicyclooctanones as inhibitors of serine beta-lactamases
US11905286B2 (en) 2018-08-09 2024-02-20 Antabio Sas Diazabicyclooctanones as inhibitors of serine beta-lactamases

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2812635B1 (fr) * 2000-08-01 2002-10-11 Aventis Pharma Sa Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens
FR2835186B1 (fr) 2002-01-28 2006-10-20 Aventis Pharma Sa Nouveaux composes heterocycliques, actifs comme inhibiteurs de beta-lactamases
FR2930553B1 (fr) 2008-04-29 2010-05-21 Novexel Composes azabicycliques, leur preparation et leur utilisation comme medicaments, notamment inhibiteurs de beta-lactamases
EP2748165B1 (en) * 2011-08-27 2016-11-02 Wockhardt Limited 1,6-diazabicyclo[3,2,1]octan-7-one derivatives and their use in the treatment of bacterial infections.
AU2012310136B2 (en) * 2011-09-13 2016-07-07 Wockhardt Limited Nitrogen containing compounds and their use
KR101946107B1 (ko) * 2012-08-25 2019-02-08 욱크하르트 리미티드 １,６-디아자비시클로〔３,２,１〕옥탄-７-온 유도체 및 세균 감염의 치료에서의 이의 용도
CN105143225A (zh) * 2013-03-08 2015-12-09 沃克哈特有限公司 一种制备(2s,5r)-7-氧代-6-磺酰氧基-2-[((3r)-哌啶-3-羰基)-肼基羰基]-1,6-二氮杂-双环[3.2.1]辛烷的方法
WO2014141132A1 (en) * 2013-03-14 2014-09-18 Naeja Pharmaceutical Inc. NEW HETEROCYCLIC COMPOUNDS AND THEIR USE AS ANTIBACTERIAL AGENTS AND β-LACTAMASE INHIBITORS

Also Published As

Publication number Publication date
US20200017496A1 (en) 2020-01-16
IL268362A (en) 2019-09-26
ZA201904998B (en) 2020-03-25
KR20190115062A (ko) 2019-10-10
CA3051972A1 (en) 2018-08-09
BR112019015834A2 (pt) 2020-03-31
WO2018141991A1 (en) 2018-08-09
CL2019002203A1 (es) 2019-11-29
JP2020506198A (ja) 2020-02-27
RU2019124705A (ru) 2021-02-05
TW201831482A (zh) 2018-09-01
EP3577117A1 (en) 2019-12-11
AU2018216243A1 (en) 2019-08-22
CN110392684A (zh) 2019-10-29

Similar Documents

Publication Publication Date Title
PH12020551760A1 (en) Pyridazinones as parp7 inhibitors
PH12020500655A1 (en) Compounds
MX2017012545A (es) Compuestos heterociclicos y su uso en la prevencion o tratamiento de las infecciones bacterianas.
WO2015003816A3 (en) Cystobactamides
TN2017000544A1 (en) 1,1,1-trifluoro-3-hydroxypropan-2-yl carbamate derivatives and 1,1,1-trifluoro-4-hydroxybutan-2-yl carbamate derivatives as magl inhibitors
GEAP202215303A (en) Chromane monobactam compounds for the treatment of bacterial infections
MY203303A (en) Compounds
PH12017501019A1 (en) Isoxazole hydromaxamic acid compounds as lpxc inhibitors
EA201990044A1 (ru) Гетероциклические соединения в качестве антибактериальных средств
MX2021014531A (es) Compuestos de aminopurina sustituida, composiciones del mismo, y metodos de tratamiento con los mismos.
PH12015502611A1 (en) Heterocyclic compounds as hedgehog signaling pathway inhibitors
ZA202002093B (en) Antibacterial compounds
NZ724798A (en) Polymyxin derivatives as antimicrobial compounds
EA201692358A1 (ru) Производные изоиндолина для применения в лечении вирусной инфекции
MX2016009248A (es) Compuestos que contienen nitrogeno y su uso como agentes antibacterianos.
MX2020006191A (es) Bacteriocinas terapeuticas.
MX2017012535A (es) Compuestos hetorociclicos novedosos y su uso en la prevencion o tratamiento de las infecciones bacterianas.
PH12016502130B1 (en) Novel pyrrolopyrimidine compound or salt thereof, pharmaceutical composition containing same, especially agent for prevention and/or treatment of tumors etc based on nae inhibitory effect
NZ735398A (en) Novel n-acyl-arylsulfonamide derivatives as aminoacyl-trna synthetase inhibitors
PH12019502277A1 (en) Crystalline forms of (s)-afoxolaner
EA201992370A1 (ru) Соединения и способы для лечения бактериальных инфекций
MX2021015514A (es) Compuesto heterociclico.
MX2017014080A (es) Compuestos heterociclicos y su uso en la prevencion o tratamiento de las infecciones bacterianas.
PH12020550222A1 (en) Gluconic acid derivatives for use in the treatment and/or prevention of microbial infections
MX2015005753A (es) Agentes antimicrobianos.