MX2019008390A - Compounds useful for treating cancer. - Google Patents
Compounds useful for treating cancer.Info
- Publication number
- MX2019008390A MX2019008390A MX2019008390A MX2019008390A MX2019008390A MX 2019008390 A MX2019008390 A MX 2019008390A MX 2019008390 A MX2019008390 A MX 2019008390A MX 2019008390 A MX2019008390 A MX 2019008390A MX 2019008390 A MX2019008390 A MX 2019008390A
- Authority
- MX
- Mexico
- Prior art keywords
- group
- alkyl
- treating cancer
- hydroxyl
- compounds useful
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 201000011510 cancer Diseases 0.000 title abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 2
- 125000003709 fluoroalkyl group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- -1 N-methylpiperazinyl group Chemical group 0.000 abstract 1
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000004428 fluoroalkoxy group Chemical group 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
- 125000002757 morpholinyl group Chemical group 0.000 abstract 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
- 125000003373 pyrazinyl group Chemical group 0.000 abstract 1
- PBMFSQRYOILNGV-UHFFFAOYSA-N pyridazine Chemical compound C1=CC=NN=C1 PBMFSQRYOILNGV-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
The present invention relates to compound (I) wherein: means a pyridazine, a pyrimidine or a pyrazine group, R independently represent a hydrogen atom, a halogen atom or a group chosen among a CN group, a hydroxyl group, a COOR1 group, a (C1-C3)fluoroalkyl group, a (C1-C3)fluoroalkoxy group, a NO2 group, a NR1R2 group, a (C1-C4)alkoxy group, a phenoxy group and a (C1-C3)alkyl group, said alkyl being optionally mono-substituted by a hydroxyl group, n is 1, 2 or 3, n is 1 or 2, R is a hydrogen atom, a halogen atom or a group chosen among a (C1-C3)alkyl group,, a hydroxyl group, a COOR1 group, a NO2 group, a NR1R2 group, a morpholinyl or a morpholino group, a N-methylpiperazinyl group, a (C1-C3)fluoroalkyl group, a (C1-C4)alkoxy group and a CN group, Z is N or C, Y is N or C, X is N or C, W is N or C, T is N or C, U is N or C, for use as an agent for preventing, inhibiting or treating cancer. Some of said compounds are new and also form part of the invention.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18655209P | 2009-06-12 | 2009-06-12 | |
| US18654409P | 2009-06-12 | 2009-06-12 | |
| EP20090305540 EP2266972A1 (en) | 2009-06-12 | 2009-06-12 | New chemical molecules that inhibit the splicing mechanism for treating diseases resulting from splicing anomalies |
| EP09162630A EP2261214A1 (en) | 2009-06-12 | 2009-06-12 | Compounds useful to treat premature aging and in particular progeria |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2019008390A true MX2019008390A (en) | 2019-09-09 |
Family
ID=56384060
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019008390A MX2019008390A (en) | 2009-06-12 | 2011-12-07 | Compounds useful for treating cancer. |
Country Status (3)
| Country | Link |
|---|---|
| JP (11) | JP6149127B2 (en) |
| HR (1) | HRP20191460T1 (en) |
| MX (1) | MX2019008390A (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10253020B2 (en) | 2009-06-12 | 2019-04-09 | Abivax | Compounds for preventing, inhibiting, or treating cancer, AIDS and/or premature aging |
| MX353776B (en) * | 2009-06-12 | 2018-01-29 | Abivax | Compounds useful for treating cancer. |
| HRP20191460T1 (en) * | 2009-06-12 | 2019-11-15 | Abivax | COMPOUNDS USEFUL FOR TREATMENT OF CANCER |
| EP2757161A1 (en) | 2013-01-17 | 2014-07-23 | Splicos | miRNA-124 as a biomarker of viral infection |
| EP2974729A1 (en) | 2014-07-17 | 2016-01-20 | Abivax | Quinoline derivatives for use in the treatment of inflammatory diseases |
| EP3669873A1 (en) | 2018-12-20 | 2020-06-24 | Abivax | Quinoline derivatives for use ine the traeatment of inflammation diseases |
| WO2023138657A1 (en) * | 2022-01-24 | 2023-07-27 | 江苏恒瑞医药股份有限公司 | Quinoline amine compound, preparation method therefor, and use thereof in medicine |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE958647C (en) * | 1952-12-28 | 1957-02-21 | Hoechst Ag | Process for the preparation of 7-amino-2-oxy-4-methyl-quinolines |
| US6177401B1 (en) * | 1992-11-13 | 2001-01-23 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften | Use of organic compounds for the inhibition of Flk-1 mediated vasculogenesis and angiogenesis |
| EE05362B1 (en) * | 2001-01-22 | 2010-12-15 | Memory Pharmaceuticals Corporation | Aniline derivatives useful as phosphodiesterase 4 inhibitors |
| AU2002950217A0 (en) * | 2002-07-16 | 2002-09-12 | Prana Biotechnology Limited | 8- Hydroxy Quinoline Derivatives |
| FR2912745A1 (en) * | 2007-02-19 | 2008-08-22 | Centre Nat Rech Scient | NEW INDOLE-DERIVED COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| CA2681481A1 (en) * | 2007-03-16 | 2008-09-25 | Mount Sinai School Of Medicine | Induction and/or maintenance of tumor dormancy by disruption of urokinase plasminogen activator receptor-integrin interaction |
| MX353776B (en) * | 2009-06-12 | 2018-01-29 | Abivax | Compounds useful for treating cancer. |
| HRP20191460T1 (en) * | 2009-06-12 | 2019-11-15 | Abivax | COMPOUNDS USEFUL FOR TREATMENT OF CANCER |
-
2010
- 2010-06-14 HR HRP20191460 patent/HRP20191460T1/en unknown
-
2011
- 2011-12-07 MX MX2019008390A patent/MX2019008390A/en unknown
-
2016
- 2016-01-15 JP JP2016006101A patent/JP6149127B2/en active Active
- 2016-01-15 JP JP2016006103A patent/JP6154922B2/en active Active
- 2016-01-15 JP JP2016006104A patent/JP6149129B2/en active Active
- 2016-01-15 JP JP2016006102A patent/JP6149128B2/en active Active
- 2016-01-15 JP JP2016006105A patent/JP6150445B2/en active Active
-
2017
- 2017-03-31 JP JP2017071704A patent/JP6336650B2/en active Active
- 2017-03-31 JP JP2017070251A patent/JP6419243B2/en active Active
- 2017-05-22 JP JP2017101011A patent/JP6378802B2/en active Active
-
2018
- 2018-06-25 JP JP2018119763A patent/JP2018162292A/en not_active Withdrawn
- 2018-06-25 JP JP2018119762A patent/JP6606577B2/en active Active
- 2018-06-25 JP JP2018119761A patent/JP6694476B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP6336650B2 (en) | 2018-06-06 |
| JP6694476B2 (en) | 2020-05-13 |
| JP6149127B2 (en) | 2017-06-14 |
| JP6149129B2 (en) | 2017-06-14 |
| JP2016128463A (en) | 2016-07-14 |
| JP2016128462A (en) | 2016-07-14 |
| JP6149128B2 (en) | 2017-06-14 |
| JP6154922B2 (en) | 2017-06-28 |
| JP2018162291A (en) | 2018-10-18 |
| JP6150445B2 (en) | 2017-06-21 |
| JP6378802B2 (en) | 2018-08-22 |
| JP6606577B2 (en) | 2019-11-13 |
| JP6419243B2 (en) | 2018-11-07 |
| JP2016135776A (en) | 2016-07-28 |
| JP2018162292A (en) | 2018-10-18 |
| HRP20191460T1 (en) | 2019-11-15 |
| JP2018162290A (en) | 2018-10-18 |
| JP2016147850A (en) | 2016-08-18 |
| JP2017137342A (en) | 2017-08-10 |
| JP2017137341A (en) | 2017-08-10 |
| JP2017222639A (en) | 2017-12-21 |
| JP2016128461A (en) | 2016-07-14 |
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