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MX2014007398A - 2, 4-diamine-pyrimidine derivative as serine/threonine kinase inhibitors. - Google Patents

2, 4-diamine-pyrimidine derivative as serine/threonine kinase inhibitors.

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Publication number
MX2014007398A
MX2014007398A MX2014007398A MX2014007398A MX2014007398A MX 2014007398 A MX2014007398 A MX 2014007398A MX 2014007398 A MX2014007398 A MX 2014007398A MX 2014007398 A MX2014007398 A MX 2014007398A MX 2014007398 A MX2014007398 A MX 2014007398A
Authority
MX
Mexico
Prior art keywords
serine
diamine
kinase inhibitors
threonine kinase
pyrimidine derivative
Prior art date
Application number
MX2014007398A
Other languages
Spanish (es)
Inventor
Wendy Lee
Ignacio Aliagas-Martin
Simon Mathieu
Joachim Rudolph
James John Crawford
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority claimed from PCT/EP2012/076531 external-priority patent/WO2013092940A1/en
Publication of MX2014007398A publication Critical patent/MX2014007398A/en

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Abstract

Compounds having the formula I wherein A, R1a, R1b, R2, R3, R4, R5, R6, R7, R8, Ra, Rb, X1, X2, X3 and n are as defined herein are inhibitors of PAK1. Also disclosed are compositions and methods for treating cancer and hyperproliferative disorders.
MX2014007398A 2011-12-22 2012-12-21 2, 4-diamine-pyrimidine derivative as serine/threonine kinase inhibitors. MX2014007398A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP61579227 2011-12-22
PCT/EP2012/076531 WO2013092940A1 (en) 2011-12-22 2012-12-21 2, 4-diamine-pyrimidine derivative as serine/threonine kinase inhibitors

Publications (1)

Publication Number Publication Date
MX2014007398A true MX2014007398A (en) 2014-08-08

Family

ID=52130938

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014007398A MX2014007398A (en) 2011-12-22 2012-12-21 2, 4-diamine-pyrimidine derivative as serine/threonine kinase inhibitors.

Country Status (1)

Country Link
MX (1) MX2014007398A (en)

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