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MX2019007248A - Enzimas de polimerizacion para reacciones de secuenciacion. - Google Patents

Enzimas de polimerizacion para reacciones de secuenciacion.

Info

Publication number
MX2019007248A
MX2019007248A MX2019007248A MX2019007248A MX2019007248A MX 2019007248 A MX2019007248 A MX 2019007248A MX 2019007248 A MX2019007248 A MX 2019007248A MX 2019007248 A MX2019007248 A MX 2019007248A MX 2019007248 A MX2019007248 A MX 2019007248A
Authority
MX
Mexico
Prior art keywords
polymerizing enzymes
sequencing reactions
nucleic acid
enzymes
polymerizing
Prior art date
Application number
MX2019007248A
Other languages
English (en)
Inventor
Reed Brian
Wadud Bhuiya Mohammad
Lackey Jeremy
M Rothberg Jonathan
Pandey Manjula
Christian Thomas
Original Assignee
Quantum Si Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quantum Si Inc filed Critical Quantum Si Inc
Publication of MX2019007248A publication Critical patent/MX2019007248A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07—Nucleotidyltransferases (2.7.7)
    • C12Y207/07007—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

Abstract

Las composiciones que comprenden las enzimas de polimerizacion recombinantes modificadas se proporcionan, junto con moleculas de acido nucleico que codifican las enzimas de polimerizacion modificadas; en algunos aspectos, se proporcionan los metodos para utilizar dichas enzimas de polimerizacion para sintetizar una molecula de acido nucleico o para secuenciar una plantilla de acido nucleico.
MX2019007248A 2016-12-19 2017-12-19 Enzimas de polimerizacion para reacciones de secuenciacion. MX2019007248A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662436410P 2016-12-19 2016-12-19
PCT/US2017/067427 WO2018118997A2 (en) 2016-12-19 2017-12-19 Polymerizing enzymes for sequencing reactions

Publications (1)

Publication Number Publication Date
MX2019007248A true MX2019007248A (es) 2019-08-16

Family

ID=61148468

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019007248A MX2019007248A (es) 2016-12-19 2017-12-19 Enzimas de polimerizacion para reacciones de secuenciacion.

Country Status (11)

Country Link
US (2) US11312944B2 (es)
EP (1) EP3555272A2 (es)
JP (2) JP2020501573A (es)
KR (2) KR20190093659A (es)
CN (1) CN110268055A (es)
AU (1) AU2017378990B2 (es)
BR (1) BR112019012181A2 (es)
CA (1) CA3047321A1 (es)
MX (1) MX2019007248A (es)
TW (1) TWI788318B (es)
WO (1) WO2018118997A2 (es)

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AU2020364058A1 (en) 2019-10-11 2022-05-26 Quantum-Si Incorporated Surface modification in the vapor phase
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Also Published As

Publication number Publication date
KR20190093659A (ko) 2019-08-09
AU2017378990A1 (en) 2019-06-20
WO2018118997A2 (en) 2018-06-28
EP3555272A2 (en) 2019-10-23
TWI788318B (zh) 2023-01-01
CA3047321A1 (en) 2018-06-28
TW201835328A (zh) 2018-10-01
JP2020501573A (ja) 2020-01-23
BR112019012181A2 (pt) 2019-11-05
US11312944B2 (en) 2022-04-26
US20180208911A1 (en) 2018-07-26
WO2018118997A3 (en) 2018-08-02
US20180362941A9 (en) 2018-12-20
US20230058852A1 (en) 2023-02-23
AU2017378990B2 (en) 2024-05-16
JP2023026651A (ja) 2023-02-24
CN110268055A (zh) 2019-09-20
KR20230052995A (ko) 2023-04-20

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