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MX2018014509A - Exosomas que contienen polipeptidos terapeuticos. - Google Patents

Exosomas que contienen polipeptidos terapeuticos.

Info

Publication number
MX2018014509A
MX2018014509A MX2018014509A MX2018014509A MX2018014509A MX 2018014509 A MX2018014509 A MX 2018014509A MX 2018014509 A MX2018014509 A MX 2018014509A MX 2018014509 A MX2018014509 A MX 2018014509A MX 2018014509 A MX2018014509 A MX 2018014509A
Authority
MX
Mexico
Prior art keywords
therapeutic polypeptides
polypeptide
evs
containing therapeutic
present
Prior art date
Application number
MX2018014509A
Other languages
English (en)
Other versions
MX378381B (es
Inventor
Wood Matthew
Hean Justin
Mager Imre
El Andaloussi Samir
Wiklander Oscar
Nordin Joel
Original Assignee
Evox Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evox Therapeutics Ltd filed Critical Evox Therapeutics Ltd
Publication of MX2018014509A publication Critical patent/MX2018014509A/es
Publication of MX378381B publication Critical patent/MX378381B/es

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  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)

Abstract

La presente invencion se refiere a un creativo mecanismo de liberacion para la entrega intracelular e intramembranal mediada por vesiculas extracelulares (VEs) de polipéptidos terapeuticos. Especificamente, la invencion se refiere a VEs que contienen constructos polipeptidicos que incluyen un polipeptido terapeutico que esta unido de forma liberable a un polipeptido exosomal. Ademas, la presente invencion corresponde a metodos de produccion, composiciones farmaceuticas, usos medicos y aplicaciones, asi como otras muchas modalidades relacionadas con las VEs.
MX2018014509A 2016-05-25 2017-05-25 Exosomas que contienen polipeptidos terapeuticos MX378381B (es)

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GBGB1609216.5A GB201609216D0 (en) 2016-05-25 2016-05-25 Exosomes comprising therapeutic polypeptides
PCT/GB2017/051479 WO2017203260A1 (en) 2016-05-25 2017-05-25 Exosomes comprising therapeutic polypeptides

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EP4523706A3 (en) 2025-05-28
CA3024020A1 (en) 2017-11-30
PT3463465T (pt) 2020-11-04
CN109715211B (zh) 2022-12-20
AU2017270932A1 (en) 2018-12-20
KR20190011279A (ko) 2019-02-01
JP6855567B2 (ja) 2021-04-07
EP3463465A1 (en) 2019-04-10
ES2836553T3 (es) 2021-06-25
US11534499B2 (en) 2022-12-27
BR112018074229A2 (pt) 2019-03-26
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CN109715211A (zh) 2019-05-03
AU2017270932B2 (en) 2021-04-29
KR102253731B1 (ko) 2021-05-24
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JP2019520852A (ja) 2019-07-25
RU2018145738A (ru) 2020-06-25
CA3024020C (en) 2022-03-08
JP2024103494A (ja) 2024-08-01
SG11201810116VA (en) 2018-12-28
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