[go: up one dir, main page]

MX2018012527A - Uso de ribosido de nicotinamida, ribosido de acido nicotinico, mononucleotido de nicotinamida y derivados de compuestos nicotinoílo en formula para lactantes. - Google Patents

Uso de ribosido de nicotinamida, ribosido de acido nicotinico, mononucleotido de nicotinamida y derivados de compuestos nicotinoílo en formula para lactantes.

Info

Publication number
MX2018012527A
MX2018012527A MX2018012527A MX2018012527A MX2018012527A MX 2018012527 A MX2018012527 A MX 2018012527A MX 2018012527 A MX2018012527 A MX 2018012527A MX 2018012527 A MX2018012527 A MX 2018012527A MX 2018012527 A MX2018012527 A MX 2018012527A
Authority
MX
Mexico
Prior art keywords
riboside
nicotinamide
nicotinic acid
infant formula
compound derivatives
Prior art date
Application number
MX2018012527A
Other languages
English (en)
Inventor
Dellinger Ryan
RHONEMUS Troy
Morris Mark
Conze Dietrich
Boileau Amy
Original Assignee
Chromadex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chromadex Inc filed Critical Chromadex Inc
Publication of MX2018012527A publication Critical patent/MX2018012527A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/13Nucleic acids or derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12Fatty acids or derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15Vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16Inorganic salts, minerals or trace elements
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/175Amino acids
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/19Dairy proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/30Dietetic or nutritional methods, e.g. for losing weight
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4415Pyridoxine, i.e. Vitamin B6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A61K31/51Thiamines, e.g. vitamin B1
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525Isoalloxazines, e.g. riboflavins, vitamin B2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00Function of food ingredients
    • A23V2200/30Foods, ingredients or supplements having a functional effect on health
    • A23V2200/32Foods, ingredients or supplements having a functional effect on health having an effect on the health of the digestive tract

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pediatric Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Fodder In General (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Dairy Products (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Feed For Specific Animals (AREA)
  • Saccharide Compounds (AREA)

Abstract

Se proporcionan métodos para suministrar al menos un compuesto seleccionado de ribósido de nicotinamida (NR), ribósido de ácido nicotinico (NAR) y mononucleótido de nicotinamida (NMN), derivados de estos o sales de estos, en combinación con al menos una de tiamina (vitamina B1), riboflavina (vitamina 82), niacina (vitamina B3) y piridoxina (vitamina 86), a un sujeto humano lactante que necesita dicho compuesto o compuestos.
MX2018012527A 2016-04-14 2017-04-14 Uso de ribosido de nicotinamida, ribosido de acido nicotinico, mononucleotido de nicotinamida y derivados de compuestos nicotinoílo en formula para lactantes. MX2018012527A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662322460P 2016-04-14 2016-04-14
PCT/US2017/027755 WO2017181102A1 (en) 2016-04-14 2017-04-14 Use of nicotinamide riboside, nicotinic acid riboside, nicotinamide mononucleotide, and nicotinoyl compound derivatives in infant formula

Publications (1)

Publication Number Publication Date
MX2018012527A true MX2018012527A (es) 2019-08-21

Family

ID=60039660

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018012527A MX2018012527A (es) 2016-04-14 2017-04-14 Uso de ribosido de nicotinamida, ribosido de acido nicotinico, mononucleotido de nicotinamida y derivados de compuestos nicotinoílo en formula para lactantes.

Country Status (12)

Country Link
US (3) US10857172B2 (es)
EP (1) EP3442527B1 (es)
JP (2) JP7061077B2 (es)
KR (2) KR20220137150A (es)
CN (2) CN115176998A (es)
AU (2) AU2017248818B2 (es)
BR (1) BR112018071074B1 (es)
CA (1) CA3021022C (es)
ES (1) ES2981479T3 (es)
MX (1) MX2018012527A (es)
WO (1) WO2017181102A1 (es)
ZA (1) ZA201807586B (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017184885A1 (en) * 2016-04-20 2017-10-26 ChromaDex Inc. Use of nicotinic acid riboside or nicotinamide ribosite derivatives, and reduced derivatives thereof, as nad+increasing precursors
BR112019010607B1 (pt) * 2016-11-29 2023-10-31 University Of Iowa Research Foundation Uso de precursores de nad e composição compreendendo os referidos precursores
WO2018191771A1 (en) * 2017-04-18 2018-10-25 Victor Chang Cardiac Research Institute Detection and treatment of congenital malformations
US11286274B2 (en) 2017-06-19 2022-03-29 Mitopower Llc Nicotinamide riboside derivatives and their uses
CN112020363A (zh) * 2017-12-22 2020-12-01 益力舒健康公司 烟酰胺核苷氯化物的结晶形式
CA3141304A1 (en) * 2018-05-22 2019-11-28 Jumpstart Fertility Pty Ltd Amino acid salts of nicotinic acid ribosides as anti-aging agents
US12508280B2 (en) * 2018-08-29 2025-12-30 Dsm Ip Assets B.V. Formulations for improving gut health
WO2020102326A1 (en) * 2018-11-13 2020-05-22 Elysium Health, Inc Methods for determining and increasing nad levels
AU2019396415B2 (en) * 2018-12-10 2023-06-01 ChromaDex Inc. Crystalline forms of nicotinoyl ribosides and derivatives thereof, and methods of preparation thereof
US11833167B2 (en) 2018-12-17 2023-12-05 Mitopower Llc Nicotinyl riboside compounds and their uses
JPWO2020166527A1 (ja) * 2019-02-12 2021-12-16 めぐみ 田中 乳幼児用飲食品、乳幼児の腸内環境の改善方法、及び乳幼児の免疫力の増強方法
MX2021010043A (es) * 2019-02-21 2022-07-19 Chromadex Inc Uso de nicotinamida ribósido, ácido nicotinico ribósido, compuestos de nicotinil ribósido reducido y derivados de compuestos de nicotinil ribósido en formulaciones.
EP3980028A1 (en) * 2019-06-05 2022-04-13 Société des Produits Nestlé S.A. Reduced nicotinamideribosides for treating/preventing skeletal muscle disease
EP4059571A4 (en) * 2019-10-11 2023-11-15 National University Corporation Shizuoka University NICOTINAMIDRIBOSIDE-PRODUCING LACTIC ACID BACTERIA AND NICOTINAMIDE MONONUCLEOTIDE AND NICOTINAMIDRIBOSIDE-PRODUCING LACTIC ACID BACTERIA
WO2021220209A1 (en) * 2020-04-30 2021-11-04 Dyadic International (Usa), Inc. Nicotinamide riboside production in filamentous fungi
EP4236948A1 (en) * 2020-10-30 2023-09-06 Société des Produits Nestlé S.A. Compositions containing nicotinamide and vitamin b6 and methods of using such compositions for treating sarcopenia and frailty
WO2022090456A1 (en) * 2020-10-30 2022-05-05 Société des Produits Nestlé S.A. Compositions containing nicotinamide and vitamin b6 and methods of using such compositions for rehabilitation
CN116322685A (zh) * 2020-10-30 2023-06-23 雀巢产品有限公司 含有烟酰胺和维生素b6的组合物以及使用此类组合物来治疗恶病质或恶病质前期的方法
CN113208117A (zh) * 2021-06-03 2021-08-06 泰州职业技术学院 一种含有nmn和牛磺酸的组合物及其应用
CN113893262A (zh) * 2021-09-29 2022-01-07 武汉英纽林生物科技有限公司 一种用于干预糖尿病前期空腹血糖偏高的nad+组合物及其制备方法和使用方法
JP2025183464A (ja) * 2022-11-04 2025-12-17 ミライラボバイオサイエンス株式会社 イヌの腸内細菌叢改善用剤
CN121152567A (zh) * 2023-05-12 2025-12-16 明治控股股份有限公司 用于促进儿童的发育的组合物
WO2025004279A1 (ja) * 2023-06-29 2025-01-02 株式会社レースホース 動物用栄養組成物

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007537246A (ja) * 2004-05-12 2007-12-20 バイオランクス カンパニー リミテッド ニコチン酸誘導体を有効成分として含む癌予防及び治療剤
CA2567848A1 (en) 2004-06-04 2006-01-05 Washington University Methods and compositions for treating neuropathies
US7572474B2 (en) * 2005-06-01 2009-08-11 Mead Johnson Nutrition Company Method for simulating the functional attributes of human milk oligosaccharides in formula-fed infants
US8075934B2 (en) * 2008-10-24 2011-12-13 Mead Johnson Nutrition Company Nutritional composition with improved digestibility
DK1957086T3 (en) 2005-11-18 2018-06-06 Cornell Res Foundation Inc NICOTINOYL RIBOSIDE COMPOSITIONS AND METHODS OF USE
AU2007339844B2 (en) 2006-12-29 2014-04-10 Commonwealth Scientific And Industrial Research Organisation Process for reducing spore levels in compositions
CN101263840B (zh) 2008-04-28 2010-06-23 内蒙古伊利实业集团股份有限公司 一种含有核糖的奶粉及其制备方法
JP4620760B2 (ja) * 2008-07-07 2011-01-26 本田技研工業株式会社 車両用キャニスタの取付構造
US8986769B2 (en) * 2008-10-24 2015-03-24 Mead Johnson Nutrition Company Methods for preserving endogenous TGF-β
US8425955B2 (en) 2009-02-12 2013-04-23 Mead Johnson Nutrition Company Nutritional composition with prebiotic component
WO2013186355A1 (en) 2012-06-15 2013-12-19 Conaris Research Institute Ag A pharmaceutical composition containing nicotinic acid and/or nicotinamide and/or tryptophan for positively influencing the intestinal microbiota
MX2012010488A (es) * 2012-09-11 2014-03-26 Nucitec Sa De Cv Formula infantil para el optimo crecimiento, proteccion gastrointestinal y proteccion inmunologica de infantes.
US20150119322A1 (en) 2013-07-31 2015-04-30 Mead Johnson Nutrition Company Nutritional compositions containing a prebiotic and lactoferrin and uses thereof
RU2016149764A (ru) 2014-06-02 2018-07-17 Глэксосмитклайн Интеллекчуал Проперти (Но.2) Лимитед Получение и применение кристаллического бета-d-никотинамида рибозида

Also Published As

Publication number Publication date
CA3021022C (en) 2024-04-23
US20170296564A1 (en) 2017-10-19
US10857172B2 (en) 2020-12-08
US20210228604A1 (en) 2021-07-29
ZA201807586B (en) 2021-04-28
JP2019513385A (ja) 2019-05-30
ES2981479T3 (es) 2024-10-09
US12433908B2 (en) 2025-10-07
AU2022287565A1 (en) 2023-02-02
KR102450537B1 (ko) 2022-10-04
WO2017181102A1 (en) 2017-10-19
CA3021022A1 (en) 2017-10-19
JP7061077B2 (ja) 2022-04-27
JP7223110B2 (ja) 2023-02-15
NZ787127A (en) 2025-03-28
AU2022287565B2 (en) 2025-06-12
NZ747149A (en) 2024-03-22
BR112018071074A2 (pt) 2019-02-12
US20230201233A1 (en) 2023-06-29
EP3442527A4 (en) 2019-12-18
CN115176998A (zh) 2022-10-14
EP3442527A1 (en) 2019-02-20
EP3442527B1 (en) 2024-06-26
AU2017248818A1 (en) 2018-11-01
BR112018071074B1 (pt) 2023-10-03
JP2022061981A (ja) 2022-04-19
CN109562104A (zh) 2019-04-02
US11524022B2 (en) 2022-12-13
KR20190018623A (ko) 2019-02-25
AU2017248818B2 (en) 2023-01-12
KR20220137150A (ko) 2022-10-11
EP3442527C0 (en) 2024-06-26

Similar Documents

Publication Publication Date Title
MX2018012527A (es) Uso de ribosido de nicotinamida, ribosido de acido nicotinico, mononucleotido de nicotinamida y derivados de compuestos nicotinoílo en formula para lactantes.
ZA202106912B (en) Use of nicotinamide riboside, nicotinic acid riboside, reduced nicotinyl riboside compounds, and nicotinyl riboside compound derivatives in formulations
ZA201807736B (en) Use of nicotinic acid riboside or nicotinamide ribosite derivatives, and reduced derivatives thereof, as nad+increasing precursors
ZA201801196B (en) Nicotinamide mononucleotide derivatives and their uses
HUE060152T2 (hu) 4-(3H-indol-5-il)-N-(piridin-2-il)pirimidin-2-amin-származékok mint proteinkináz inhibitorok, elõállítási eljárásuk és gyógyászati alkalmazásuk
ZA201706918B (en) Nicotinic acid riboside or nicotinamide riboside compositions, reduced derivatives thereof, and the use thereof
NZ712174A (en) 4-amino-6-(heterocyclic)picolinates and 6-amino-2-(heterocyclic) pyrimidine-4-carboxylates and their use as herbicides
MY196292A (en) Steroid Derivative Fxr Agonist
MX375381B (es) Piridinonas anti-fibroticas.
MX375030B (es) Compuestos de n,6-bis(aril o heteroaril)-1,3,5-triazin-2,4-diamina como inhibidores de idh2 mutantes para el tratamiento de cancer.
GEP201706761B (en) 6-(5-hydroxy-1h-pyrazol-1-yl) nicotinamide derivatives and their use as phd inhibitors
MY184855A (en) 4-amino-6-(heterocyclic)picolinates and 6-amino-2-(heterocyclic)pyrimidine-4-carboxylates and their use as herbicides
ZA201901321B (en) Tablet compositions
MX2016009581A (es) Derivados de 6-fenil- o 6-(piridin-3-il) indazol y metodos de uso.
MX2016005759A (es) Derivados de piridina sustituidos, utiles como inhibidores de glucogeno sintasa cinasa 3 (gsk-3).
EP3428158A4 (en) SALT OF PYRIDINYL-AMINO-PYRIMIDINE DERIVATIVE, METHOD OF MANUFACTURING THEREOF AND THE APPLICATION THEREOF
IL248272A0 (en) A new manufacturing process for triazine, pyrimidine and pyridine derivatives
MX2014011833A (es) Metodos para preparar 3-sustituido. 6-trifluorometil piridinas y metodos para la utilizacion de 6-triclorometil piridinas halogenadas.
SG11201806596TA (en) Pyridine derivative inhibiting raf kinase and vascular endothelial growth factor receptor, method for preparing same, pharmaceutical composition containing same, and use thereof
BR112015032534A2 (pt) usos de composto ou de sal, solvato ou pró-droga farmaceuticamente aceitável do mesmo, composições farmacêuticas e métodos para prevenir e/ou tratar encefalopatia traumática crônica ou condição relacionada em indivíduo e para tratar indivíduo com lesão de concussão
IN2015DN02601A (es)
IL263652A (en) History of bicyclic pyridine, pyrazine, and pyrimidine as PI3K inhibitors in the cell
IL259872A (en) Herbicidal preparations containing 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylic acid, flurozolam and pyrozolam or their derivatives