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MX2018012334A - Microaguja que usa metal bioabsorbible. - Google Patents

Microaguja que usa metal bioabsorbible.

Info

Publication number
MX2018012334A
MX2018012334A MX2018012334A MX2018012334A MX2018012334A MX 2018012334 A MX2018012334 A MX 2018012334A MX 2018012334 A MX2018012334 A MX 2018012334A MX 2018012334 A MX2018012334 A MX 2018012334A MX 2018012334 A MX2018012334 A MX 2018012334A
Authority
MX
Mexico
Prior art keywords
microneedle
bioabsorbable metal
substrate portion
needle
substrate
Prior art date
Application number
MX2018012334A
Other languages
English (en)
Inventor
Youn Cho Sung
Tack Kim Jong
Wook Choo Hyun
Original Assignee
Labnpeople Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labnpeople Co Ltd filed Critical Labnpeople Co Ltd
Priority claimed from PCT/KR2017/003775 external-priority patent/WO2017176069A2/ko
Publication of MX2018012334A publication Critical patent/MX2018012334A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/02Inorganic materials
    • A61L31/022Metals or alloys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148Materials at least partially resorbable by the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602Type of release, e.g. controlled, sustained, slow
    • A61L2300/604Biodegradation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606Coatings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046Solid microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053Methods for producing microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061Methods for using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

La presente invención incluye: una porción de sustrato; una porción de aguja provista en la porción de sustrato y que sobresale de la porción de sustrato que será insertada en la piel; y una porción perforada provista en una unión entre la porción de aguja y la porción de sustrato, en donde cualquiera de la porción de sustrato y la porción de aguja está hecha del metal bioabsorbible.
MX2018012334A 2016-04-07 2017-04-06 Microaguja que usa metal bioabsorbible. MX2018012334A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20160042690 2016-04-07
KR1020160181865A KR101879851B1 (ko) 2016-04-07 2016-12-29 생체흡수성 금속을 이용한 마이크로 니들
PCT/KR2017/003775 WO2017176069A2 (ko) 2016-04-07 2017-04-06 생체흡수성 금속을 이용한 마이크로 니들

Publications (1)

Publication Number Publication Date
MX2018012334A true MX2018012334A (es) 2019-03-28

Family

ID=60297749

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2018012334A MX2018012334A (es) 2016-04-07 2017-04-06 Microaguja que usa metal bioabsorbible.
MX2018012236A MX2018012236A (es) 2016-04-07 2017-04-07 Microaguja que utiliza metal biodegradable.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2018012236A MX2018012236A (es) 2016-04-07 2017-04-07 Microaguja que utiliza metal biodegradable.

Country Status (9)

Country Link
US (2) US20190151638A1 (es)
EP (2) EP3441107B1 (es)
JP (2) JP6995830B2 (es)
KR (5) KR20170115429A (es)
CN (2) CN109069812B (es)
BR (1) BR112018070666A2 (es)
ES (2) ES2863905T3 (es)
MX (2) MX2018012334A (es)
PL (2) PL3441107T3 (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20170115429A (ko) * 2016-04-07 2017-10-17 랩앤피플주식회사 생체분해성 금속을 이용한 마이크로 니들
CN116726371A (zh) * 2016-08-03 2023-09-12 沃达瑞公司 微阵列和方法
KR102119675B1 (ko) * 2017-12-11 2020-06-05 랩앤피플주식회사 고밀도 마이크로 니들
KR102022968B1 (ko) * 2018-01-12 2019-09-19 주식회사 에스엔비아 마이크로 니들 시트 구조 및 그 제조방법
KR102094744B1 (ko) * 2018-01-26 2020-03-30 가천대학교 산학협력단 마이크로 니들 및 이의 제조방법
WO2019190267A1 (ko) * 2018-03-30 2019-10-03 랩앤피플주식회사 멀티형 마이크로 니들
KR102291392B1 (ko) * 2018-03-30 2021-08-20 랩앤피플주식회사 멀티형 마이크로 니들
KR102310566B1 (ko) * 2018-05-21 2021-10-08 랩앤피플주식회사 여드름 완화 및 예방용 패치
WO2019225948A1 (ko) 2018-05-21 2019-11-28 랩앤피플주식회사 여드름 완화 및 예방용 패치
KR102114474B1 (ko) * 2018-06-26 2020-05-22 랩앤피플주식회사 백신 접종 피하 삽입용 생체흡수성 약물 전달 캡슐
KR102651395B1 (ko) * 2018-07-05 2024-03-26 랩앤피플주식회사 여드름 완화 및 예방용 화장품 조성물
WO2020060159A1 (ko) * 2018-09-17 2020-03-26 랩앤피플주식회사 매선요법용 로프 및 이를 포함하는 매선요법용 니들 기구
KR102310568B1 (ko) * 2018-09-17 2021-10-08 랩앤피플주식회사 매선요법용 로프 및 이를 포함하는 매선요법용 니들 기구
KR102194089B1 (ko) * 2019-03-18 2020-12-22 랩앤피플주식회사 항산화 활성 및 미백 효과를 갖는 플렉시블 금속 패치 및 그 사용방법
CN109876197B (zh) * 2019-04-09 2024-05-10 珠海天威增材有限公司 一种3d打印皮肤及其制备方法
KR102258194B1 (ko) * 2019-08-08 2021-06-02 (주) 반도체로박 침 기구
US20220176096A1 (en) * 2019-09-10 2022-06-09 The Trustees Of Columbia University In The City Of New York Microneedles to deliver therapeutic agent across membranes
JP2021040977A (ja) * 2019-09-11 2021-03-18 株式会社ライトニックス 薬物投与デバイス
KR102414580B1 (ko) * 2020-07-17 2022-07-01 한국과학기술연구원 수술 전 감염 방지를 위한 마이크로니들 패치 및 마이크로니들 패치를 이용한 수술 전처리 방법
KR102674799B1 (ko) * 2020-11-04 2024-06-17 한국재료연구원 고강도 고내식 생분해성 마그네슘 합금 및 이를 이용하는 임플란트
EP4215222A4 (en) * 2020-11-04 2025-08-20 Korea Institute Materials Science HIGH-STRENGTH, HIGHLY ANTI-CORROSIVE, BIODEGRADABLE MAGNESIUM ALLOY AND IMPLANT USING IT
CN112274771B (zh) * 2020-11-26 2022-04-19 南京鼓楼医院 一种仿火箭的微针微马达及其制备方法
KR102593524B1 (ko) * 2021-01-29 2023-10-25 김병준 환경오염 방지 및 야생동물을 보호하기 위한 마스크
KR102565721B1 (ko) * 2021-03-15 2023-08-11 주식회사 비즈엔몰드 피부 약물 주입기용 바늘
WO2023228378A1 (ja) * 2022-05-26 2023-11-30 日本電信電話株式会社 生体組織貼付けパッチ
KR20230172308A (ko) * 2022-06-15 2023-12-22 랩앤피플주식회사 피부 부착성이 우수한 여드름 완화 및 예방용 패치
KR102858745B1 (ko) * 2022-09-19 2025-09-11 랩앤피플주식회사 고용량의 약물 전달이 가능한 스탬프형 약물전달장치
CN119894572A (zh) 2022-09-20 2025-04-25 实验室和人们 包含生物分解性金属的自生电流皮肤贴片
CN115887349A (zh) * 2022-09-27 2023-04-04 上海交通大学 一种生物降解镁氢微针
DE102023102257A1 (de) * 2023-01-31 2024-08-01 Forschungszentrum Jülich GmbH Herstellung dreidimensional strukturierten elektrodenlagen, insbesondere im kirigami-prinzip

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20040020889A (ko) 2001-04-20 2004-03-09 알자 코포레이션 유용한 약물을 갖는 코팅을 포함하는 미세돌출부 어레이
SE0102736D0 (sv) * 2001-08-14 2001-08-14 Patrick Griss Side opened out-of-plane microneedles for microfluidic transdermal interfacing and fabrication process of side opened out-of-plane microneedles
JP2006500974A (ja) * 2002-06-28 2006-01-12 アルザ・コーポレーシヨン 被覆され微細突起物を有する経皮的薬物送達装置
BRPI0413360A (pt) * 2003-08-04 2006-10-10 Alza Corp método e dispositivo para aumentar o fluxo de agentes transdérmicos
CN100540086C (zh) * 2004-03-12 2009-09-16 新加坡科技研究局 用来制造侧开口微型针的方法及模具
US20060177494A1 (en) 2005-01-31 2006-08-10 Micheal Cormier Coated microprojections having reduced variability and method for producing same
US20060253078A1 (en) * 2005-04-25 2006-11-09 Wu Jeffrey M Method of treating skin disorders with stratum corneum piercing device
US20060258973A1 (en) * 2005-04-27 2006-11-16 Kevin Volt Micro-current Iontophoretic Percutaneous Absorptive Patch
EP1893130A4 (en) * 2005-06-17 2015-08-26 Georgia Tech Res Inst COATED MICROSTRUCTURES AND METHOD FOR THE PRODUCTION THEREOF
JP2007014588A (ja) 2005-07-08 2007-01-25 Nano Device & System Research Inc 経皮投与装置,経皮投与装置製造用金型
DE102005060203B4 (de) 2005-12-14 2009-11-12 Gkss-Forschungszentrum Geesthacht Gmbh Biokompatibler Magnesiumwerkstoff, Verfahren zu seiner Herstellung und seiner Verwendung
US7658728B2 (en) * 2006-01-10 2010-02-09 Yuzhakov Vadim V Microneedle array, patch, and applicator for transdermal drug delivery
WO2008020633A1 (en) * 2006-08-18 2008-02-21 Toppan Printing Co., Ltd. Microneedle and microneedle patch
CN102512711A (zh) * 2006-09-22 2012-06-27 友和安股份公司 由生物可降解金属构成的植入物及其制造方法
JPWO2008062832A1 (ja) * 2006-11-22 2010-03-04 凸版印刷株式会社 マイクロニードルアレイ及びマイクロニードルアレイの製造方法
US8778012B2 (en) * 2012-11-27 2014-07-15 Cormatrix Cardiovascular, Inc. ECM constructs for tissue regeneration
JP2008284318A (ja) * 2007-05-15 2008-11-27 Kosumedei Seiyaku Kk 生体由来物質からなる投薬用微細針
JP5034777B2 (ja) * 2007-08-22 2012-09-26 凸版印刷株式会社 針状体の作製方法ならびに製造方法及び針状体
DE102008003453A1 (de) * 2008-01-08 2009-07-09 Robert Bosch Gmbh Verfahren zur Herstellung poröser Mikrostrukturen, nach diesem Verfahren hergestellte poröse Mikrostrukturen sowie deren Verwendung
US20090326447A1 (en) * 2008-06-27 2009-12-31 Joshi Ashok V Transdermal Delivery Apparatus and Method
JP2010069270A (ja) * 2008-09-17 2010-04-02 Yoshiichi Tobinaga 機能剤投与デバイス、その製造方法及び製造装置
US20110014181A1 (en) * 2009-07-20 2011-01-20 Medtronic Vascular, Inc. Microneedle Delivery Device and Methods of Using Same
JP2011083387A (ja) 2009-10-14 2011-04-28 Kyushu Institute Of Technology 針状体の製造方法並びに針状体および針状体保持シート
KR20110065391A (ko) * 2009-12-07 2011-06-15 유앤아이 주식회사 마그네슘 합금을 이용한 약물 전달체
EP2540337B1 (en) * 2010-02-24 2019-04-03 Hisamitsu Pharmaceutical Co., Inc. Micro-needle device and preparation method
JP2013529507A (ja) * 2010-06-21 2013-07-22 ゾリオン メディカル インコーポレイテッド 生体吸収性インプラント
AU2012220564A1 (en) * 2011-02-23 2013-08-29 Ams Research Corporation Drug releasing pelvic treatment system and method
JP2012217653A (ja) * 2011-04-08 2012-11-12 Asti Corp マイクロニードルとマイクロニードルアレイとマイクロニードルアレイ製造方法
US10624847B2 (en) * 2011-08-02 2020-04-21 AnPac BioMedical Science Co., Ltd. Decomposable apparatus and methods for fabricating same
CN104379209B (zh) * 2012-06-12 2016-11-09 久光制药株式会社 微型针贴布
US9248273B2 (en) * 2012-06-18 2016-02-02 Axion Biosystems, Inc. 3D microelectrode device for live tissue applications
AU2013283537A1 (en) * 2012-06-26 2014-11-06 Biotronik Ag Magnesium-zinc-calcium alloy, method for production thereof, and use thereof
US10246763B2 (en) 2012-08-24 2019-04-02 The Regents Of The University Of California Magnesium-zinc-strontium alloys for medical implants and devices
US9469889B2 (en) 2012-08-31 2016-10-18 DePuy Synthes Products, Inc. Ultrapure magnesium alloy with adjustable degradation rate
CN110025881A (zh) * 2012-09-13 2019-07-19 亚夫拉罕·阿米尔 用于皮肤改善的递送装置和方法
US11376349B2 (en) 2012-10-05 2022-07-05 University of Pittsburgh—of the Commonwealth System of Higher Education Biodegradable iron-containing compositions, methods of preparing and applications therefor
US9526884B2 (en) * 2012-11-16 2016-12-27 City University Of Hong Kong Mechanically robust fast-dissolving microneedles for transdermal drug and vaccine delivery
CN105073178B (zh) * 2012-12-21 2019-07-30 考里安国际公司 用于治疗剂递送的微阵列及其使用方法
CN202987775U (zh) * 2012-12-27 2013-06-12 浙江诚德包装有限公司 设有易撕线开口的软包装袋
SG11201506326YA (en) 2013-02-13 2015-09-29 Hisamitsu Pharmaceutical Co Microneedle coating composition and microneedle device
CN105142687B (zh) * 2013-02-15 2017-12-08 波士顿科学国际有限公司 用于内假体的生物溶蚀性镁合金微结构
KR102253200B1 (ko) * 2013-03-14 2021-05-21 디퍼이 신테스 프로덕츠, 인코포레이티드 조정가능한 분해율을 갖는 마그네슘 합금
CN103203072B (zh) * 2013-03-25 2015-05-20 清华大学 金属微针阵列柔性贴片、经皮给药器件及经皮给药贴片
CN105126240A (zh) * 2014-06-03 2015-12-09 陈彦彪 一种可降解超微针片
KR101703050B1 (ko) 2014-07-10 2017-02-07 주식회사 주빅 경피전달용 미세돌기 구조체
CN104212998B (zh) * 2014-08-21 2017-02-01 北京大学 一种Zn‑Mg系锌合金及其制备方法与应用
KR101785766B1 (ko) 2014-11-14 2017-10-18 가천대학교 산학협력단 코팅 마이크로니들의 생산 방법 및 그 방법에 의하여 생산된 코팅 마이크로니들
US10792857B2 (en) * 2015-03-13 2020-10-06 The University Of North Carolina At Chapel Hill Polymeric microneedles and rapid additive manufacturing of the same
KR101622388B1 (ko) 2015-10-21 2016-05-19 한국과학기술원 실리콘 마이크로 니들 스탬프 및 그 제조방법
KR20170115429A (ko) * 2016-04-07 2017-10-17 랩앤피플주식회사 생체분해성 금속을 이용한 마이크로 니들

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