MX2018010395A - Formulaciones topicas que contienen cliclosporina y usos de las mismas. - Google Patents
Formulaciones topicas que contienen cliclosporina y usos de las mismas.Info
- Publication number
- MX2018010395A MX2018010395A MX2018010395A MX2018010395A MX2018010395A MX 2018010395 A MX2018010395 A MX 2018010395A MX 2018010395 A MX2018010395 A MX 2018010395A MX 2018010395 A MX2018010395 A MX 2018010395A MX 2018010395 A MX2018010395 A MX 2018010395A
- Authority
- MX
- Mexico
- Prior art keywords
- cliclosporine
- formulations containing
- same
- formulations
- topical formulations
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
El presente documento se proporcionan formulaciones para formulaciones oftálmicas tópicas que contienen de 0.087 a 0.093% en peso de ciclosporina, y métodos de hacer y usar tales formulaciones. En algunos aspectos y modalidades las formulaciones pueden incluir un lípido de polioxilo o ácido graso, y/o un alcohol polialcoxilado y pueden incluir nanomicelios. También se incluyen en el presente documento métodos para tratar o prevenir enfermedades o condiciones, tales como enfermedades o afecciones oculares.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662301576P | 2016-02-29 | 2016-02-29 | |
| US201662302058P | 2016-03-01 | 2016-03-01 | |
| US201662302730P | 2016-03-02 | 2016-03-02 | |
| US201662311177P | 2016-03-21 | 2016-03-21 | |
| PCT/US2017/020008 WO2017151657A1 (en) | 2016-02-29 | 2017-02-28 | Topical cyclosporine-containing formulations and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2018010395A true MX2018010395A (es) | 2018-11-29 |
Family
ID=59744365
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018010395A MX2018010395A (es) | 2016-02-29 | 2017-02-28 | Formulaciones topicas que contienen cliclosporina y usos de las mismas. |
| MX2024010721A MX2024010721A (es) | 2016-02-29 | 2018-08-29 | Formulaciones topicas que contienen ciclosporina y usos de las mismas. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2024010721A MX2024010721A (es) | 2016-02-29 | 2018-08-29 | Formulaciones topicas que contienen ciclosporina y usos de las mismas. |
Country Status (21)
| Country | Link |
|---|---|
| US (4) | US10918694B2 (es) |
| EP (2) | EP4410312A3 (es) |
| JP (3) | JP7072517B2 (es) |
| KR (1) | KR102766771B1 (es) |
| CN (2) | CN119185511A (es) |
| AU (2) | AU2017227585C1 (es) |
| BR (1) | BR112018067946A8 (es) |
| CA (1) | CA3015626A1 (es) |
| DK (1) | DK3423076T3 (es) |
| ES (1) | ES2981702T3 (es) |
| FI (1) | FI3423076T3 (es) |
| IL (1) | IL268056A (es) |
| MX (2) | MX2018010395A (es) |
| NZ (2) | NZ755442A (es) |
| PL (1) | PL3423076T3 (es) |
| PT (1) | PT3423076T (es) |
| RU (1) | RU2747455C2 (es) |
| SA (1) | SA519410114B1 (es) |
| SG (1) | SG11201906729RA (es) |
| WO (1) | WO2017151657A1 (es) |
| ZA (1) | ZA201904704B (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2914472C (en) | 2012-08-24 | 2019-09-03 | Ashim K. Mitra | Ophthalmic formulation of polyoxyl lipid or polyoxyl fatty acid and treatment of ocular conditions |
| US11324800B2 (en) | 2015-01-15 | 2022-05-10 | Wellspring Ophthalmics, Inc. | Aqueous suspensions of cyclosporin |
| US20200237859A1 (en) | 2019-01-25 | 2020-07-30 | Newport Research, Inc. | Aqueous suspensions of cyclosporin |
| PT3373976T (pt) | 2015-11-10 | 2024-04-02 | Sun Pharmaceutical Ind Ltd | Formulações tópicas e suas utilizações |
| RU2747455C2 (ru) | 2016-02-29 | 2021-05-05 | Сан Фарма Глобал Фзе | Циклоспорин-содержащие лекарственные формы для наружного применения и их применения |
| CN112957450A (zh) * | 2019-12-20 | 2021-06-15 | 艾棣维欣(苏州)生物制药有限公司 | 一种难溶性药物的水溶液及其制备方法 |
| AU2022295164A1 (en) | 2021-06-14 | 2024-01-25 | Sun Pharmaceutical Industries Limited | Cyclosporine formulations for use in patients undergoing cataract surgery |
| AU2021267217A1 (en) * | 2021-08-20 | 2024-02-29 | Sun Pharmaceutical Industries Limited | Stable cyclosporine ophthalmic formulation and manufacturing process thereof |
| WO2024042550A1 (en) * | 2022-08-25 | 2024-02-29 | Sentiss Pharma Private Limited | Ophthalmic combination composition |
| KR20250096644A (ko) * | 2022-11-04 | 2025-06-27 | 클라리스 바이오, 인크. | 크로마칼림의 국소 안구 전달 |
| WO2024246776A1 (en) | 2023-05-29 | 2024-12-05 | Sun Pharmaceutical Industries Limited | Stable cyclosporine ophthalmic formulation and manufacturing process thereof |
Family Cites Families (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0642332T3 (da) * | 1992-05-13 | 1997-06-16 | Sandoz Ltd | Ophthalmiske præparater indeholdende cyclosporin |
| NZ247516A (en) | 1993-04-28 | 1995-02-24 | Bernard Charles Sherman | Water dispersible pharmaceutical compositions comprising drug dissolved in solvent system comprising at least one alcohol and at least one surfactant |
| US5484597A (en) | 1993-07-30 | 1996-01-16 | Chesebrough-Pond's Usa Co. | Clear hydroalcholic cosmetic microemulsions |
| NZ280689A (en) | 1995-12-15 | 1997-08-22 | Bernard Charles Sherma Sherman | Pharmaceutical composition comprising a cyclosporipharmaceutical composition comprising a cyclosporin; a tocol, tocopherol or tocotrienol; and propylen; a tocol, tocopherol or tocotrienol; and propylene carbonate or polyethylene glycol ne carbonate or polyethylene glycol |
| MX9701946A (es) | 1997-03-14 | 1998-04-30 | Arturo Jimenez Bayardo | Solucion oftalmica transportadora. |
| US7678836B2 (en) | 1999-11-04 | 2010-03-16 | Fxs Ventures, Llc | Method for rendering a contact lens wettable |
| US7732404B2 (en) | 1999-12-30 | 2010-06-08 | Dexcel Ltd | Pro-nanodispersion for the delivery of cyclosporin |
| US20030176356A1 (en) | 2001-04-24 | 2003-09-18 | University Of North Texas Health Science Center | Endothelin antagonists and endothelin-converting enzyme inhibitors for the treatment of glaucoma |
| KR100978836B1 (ko) | 2001-10-19 | 2010-08-30 | 이소테크니카 인코포레이티드 | 신규한 시클로스포린 유사체 미세유화액 예비농축물 |
| WO2004069181A2 (en) | 2003-02-03 | 2004-08-19 | Pharmacia Corporation | Composition for the treatment of intraocular pressure |
| JP2004238346A (ja) | 2003-02-07 | 2004-08-26 | Shiono Chemical Co Ltd | トラニラストの安定な水溶液製剤 |
| AU2003228126A1 (en) | 2003-05-02 | 2004-11-23 | Arturo Jimenez Bayardo | Method of preparing an aqueous solution of cyclosporin-a and resulting aqueous solution |
| US7087237B2 (en) | 2003-09-19 | 2006-08-08 | Advanced Ocular Systems Limited | Ocular solutions |
| ATE412400T1 (de) | 2004-11-09 | 2008-11-15 | Novagali Pharma Sa | Öl-in-wasser-emulsion mit niedriger konzentration des kationischen mittels und positivem zetapotential |
| KR20080029974A (ko) | 2005-06-09 | 2008-04-03 | 산텐 세이야꾸 가부시키가이샤 | 로플루밀라스트 점안액 |
| NZ562109A (en) | 2005-06-16 | 2011-03-31 | Myrexis Inc | Pharmaceutical compositions containing substituted (4-Phenyl)-methyl-(quinazolin-4-yl)-amine compounds, uses thereof, and methods of preparing the same |
| US20070015691A1 (en) * | 2005-07-13 | 2007-01-18 | Allergan, Inc. | Cyclosporin compositions |
| EP1904056B1 (en) | 2005-07-18 | 2009-04-29 | Minu, L.L.C. | Use of a macrolide to restore corneal sensation |
| US10137083B2 (en) | 2006-03-07 | 2018-11-27 | SGN Nanopharma Inc | Ophthalmic preparations |
| JPWO2007126110A1 (ja) | 2006-04-24 | 2009-09-17 | ナノキャリア株式会社 | 低分子薬物内包ポリマーミセルの製造方法 |
| JPWO2007136134A1 (ja) | 2006-05-23 | 2009-10-01 | ナノキャリア株式会社 | 疎水性薬物内包ポリマーミセルの製造方法 |
| US8147868B2 (en) | 2006-07-18 | 2012-04-03 | Nanocarrier Co., Ltd. | Physiologically active polypeptide- or protein-encapsulating polymer micelles, and method for production of the same |
| US20100310462A1 (en) | 2007-04-18 | 2010-12-09 | Biochromix Ab | Binding of pathological forms of proteins using conjugated polyelectrolytes |
| US8512687B2 (en) | 2007-07-09 | 2013-08-20 | Novagali Pharma Sa | Oil in water emulsion comprising NSAIDs and quaternary ammonium halides |
| WO2009028674A1 (ja) | 2007-08-29 | 2009-03-05 | Wakamoto Pharmaceutical Co., Ltd. | ラタノプロスト含有水性医薬組成物 |
| MX2007011165A (es) | 2007-09-12 | 2009-03-11 | Arturo Jimenez Bayardo | Composición farmacéutica estable de timolol, dorzolamida y brimonidina. |
| AU2008310956B2 (en) | 2007-10-08 | 2014-08-07 | Aurinia Pharmaceuticals Inc. | Ophthalmic compositions comprising calcineurin inhibitors or mTOR inhibitors |
| BRPI0822221A2 (pt) | 2008-01-04 | 2015-06-23 | Alcon Pharmaceuticals Ltd | Composições aquosas e estáveis de ciclosporina |
| TWI544927B (zh) | 2008-03-17 | 2016-08-11 | 愛爾康研究有限公司 | 具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物 |
| KR20160123400A (ko) | 2008-05-28 | 2016-10-25 | 알콘 리서치, 리미티드 | 자기보존 에멀젼 |
| EP2127638A1 (en) | 2008-05-30 | 2009-12-02 | Santen Pharmaceutical Co., Ltd | Method and composition for treating ocular hypertension and glaucoma |
| BRPI1010175A2 (pt) | 2009-06-02 | 2016-03-29 | Keller Brian Charles | "composição química que inclui um conjugado de lipídio-peg e lipossoma" |
| AU2010259184B2 (en) | 2009-06-09 | 2015-08-13 | Aurinia Pharmaceuticals Inc. | Topical drug delivery systems for ophthalmic use |
| MX2012003296A (es) | 2009-09-17 | 2012-04-20 | Senju Pharma Co | Gotas oculares acuosas que contienen latanoprost, y metodo para inhibir la adsorcion de latanoprost a una resina. |
| US8637569B2 (en) | 2009-10-22 | 2014-01-28 | Api Genesis, Llc | Methods of increasing solubility of poorly soluble compounds and methods of making and using formulations of such compounds |
| WO2011106697A1 (en) | 2010-02-25 | 2011-09-01 | Schepens Eye Research Institute | Therapeutic compositions for the treatment of dry eye disease |
| WO2011138801A1 (en) | 2010-05-07 | 2011-11-10 | Sun Pharma Advanced Research Company Ltd. | Novel ophthalmic compositions |
| US20130065888A1 (en) | 2011-08-15 | 2013-03-14 | Biserka Cetina-Cizmek | Ophthalmic formulations and processes for their preparation |
| US9278132B2 (en) | 2012-02-13 | 2016-03-08 | Bausch & Lomb Incorporated | Ophthalmic pharmaceutical compositions and methods of making and using same |
| KR101211902B1 (ko) | 2012-04-30 | 2012-12-13 | 주식회사 휴온스 | 사이클로스포린 함유 무자극성 나노에멀젼 안약 조성물 |
| RU2014149993A (ru) | 2012-05-11 | 2016-07-10 | Сипла Лимитед | Фармацевтическая композиция |
| CA2914472C (en) | 2012-08-24 | 2019-09-03 | Ashim K. Mitra | Ophthalmic formulation of polyoxyl lipid or polyoxyl fatty acid and treatment of ocular conditions |
| WO2014126997A1 (en) | 2013-02-13 | 2014-08-21 | The Research Foundation For The State University Of New York | Glaucoma treatment |
| EA201692402A1 (ru) * | 2014-05-23 | 2017-03-31 | Окьюлар Текнолоджис Сарл | Лекарственные формы для местного применения и их использование |
| US20150352176A1 (en) * | 2014-06-06 | 2015-12-10 | Newport Research, Inc. | Oil-free and fat-free aqueous suspensions of cyclosporin |
| US9421199B2 (en) | 2014-06-24 | 2016-08-23 | Sydnexis, Inc. | Ophthalmic composition |
| US20180133217A1 (en) | 2015-05-04 | 2018-05-17 | Ocular Technologies Sarl | Topical formulations and uses thereof |
| PT3373976T (pt) * | 2015-11-10 | 2024-04-02 | Sun Pharmaceutical Ind Ltd | Formulações tópicas e suas utilizações |
| WO2017083410A1 (en) | 2015-11-12 | 2017-05-18 | Ocular Technologies Sarl | Topical formulations and uses thereof |
| RU2747455C2 (ru) | 2016-02-29 | 2021-05-05 | Сан Фарма Глобал Фзе | Циклоспорин-содержащие лекарственные формы для наружного применения и их применения |
| WO2017152129A2 (en) | 2016-03-03 | 2017-09-08 | Ocular Technologies Sarl | Treatment of glaucoma and/or retinal diseases and formulations useful therefore |
-
2017
- 2017-02-28 RU RU2019130403A patent/RU2747455C2/ru active
- 2017-02-28 MX MX2018010395A patent/MX2018010395A/es unknown
- 2017-02-28 SG SG11201906729RA patent/SG11201906729RA/en unknown
- 2017-02-28 DK DK17760643.1T patent/DK3423076T3/da active
- 2017-02-28 KR KR1020187027785A patent/KR102766771B1/ko active Active
- 2017-02-28 CN CN202411358894.1A patent/CN119185511A/zh active Pending
- 2017-02-28 WO PCT/US2017/020008 patent/WO2017151657A1/en not_active Ceased
- 2017-02-28 ES ES17760643T patent/ES2981702T3/es active Active
- 2017-02-28 PT PT177606431T patent/PT3423076T/pt unknown
- 2017-02-28 CN CN201780026587.5A patent/CN109843316A/zh active Pending
- 2017-02-28 NZ NZ755442A patent/NZ755442A/en active IP Right Revival
- 2017-02-28 US US16/079,928 patent/US10918694B2/en active Active
- 2017-02-28 PL PL17760643.1T patent/PL3423076T3/pl unknown
- 2017-02-28 CA CA3015626A patent/CA3015626A1/en active Pending
- 2017-02-28 EP EP24169238.3A patent/EP4410312A3/en active Pending
- 2017-02-28 JP JP2018545269A patent/JP7072517B2/ja active Active
- 2017-02-28 BR BR112018067946A patent/BR112018067946A8/pt unknown
- 2017-02-28 NZ NZ785158A patent/NZ785158A/en unknown
- 2017-02-28 EP EP17760643.1A patent/EP3423076B1/en active Active
- 2017-02-28 AU AU2017227585A patent/AU2017227585C1/en active Active
- 2017-02-28 FI FIEP17760643.1T patent/FI3423076T3/fi active
-
2018
- 2018-08-29 MX MX2024010721A patent/MX2024010721A/es unknown
-
2019
- 2019-07-14 IL IL268056A patent/IL268056A/en unknown
- 2019-07-17 ZA ZA2019/04704A patent/ZA201904704B/en unknown
- 2019-09-12 SA SA519410114A patent/SA519410114B1/ar unknown
-
2021
- 2021-01-07 US US17/143,863 patent/US20210145924A1/en not_active Abandoned
-
2022
- 2022-05-10 JP JP2022077492A patent/JP7547411B2/ja active Active
- 2022-05-11 AU AU2022203135A patent/AU2022203135B2/en active Active
- 2022-09-26 US US17/935,177 patent/US11951153B2/en active Active
-
2024
- 2024-02-28 US US18/590,539 patent/US20240197818A1/en active Pending
- 2024-08-28 JP JP2024146154A patent/JP2024161602A/ja active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2018010395A (es) | Formulaciones topicas que contienen cliclosporina y usos de las mismas. | |
| MX2015002239A (es) | Formulacion oftalmica de lipido polioxilo o de acido graso polioxilo y tratamiento de padecimientos oculares. | |
| MX2016015211A (es) | Formulaciones topicas y usos de las mismas. | |
| CO2019006291A2 (es) | Composiciones de aminoácidos y métodos de tratamiento de enfermedades hepáticas | |
| CL2019000586A1 (es) | Composiciones de toxinas clostridiales no proteicas. | |
| CL2018001089A1 (es) | Sales de valbenazina y polimorfos de las mismas. | |
| MX2017016655A (es) | Formulaciones oftalmicas de inhibidores de tirosina quinasa, metodos de uso de las mismas y metodos de preparacion de las mismas. | |
| DOP2016000298A (es) | Pirazolopiridinas y pirazolopirimidinas | |
| MX2019015311A (es) | Composiciones de ésteres de ácido cannabidiólico y usos de las mismas. | |
| BR112015021888A8 (pt) | inibidores de dna-pk, seus usos e composição farmacêutica | |
| AR102198A1 (es) | Proceso para reducir partículas subvisibles en una formulación farmacéutica | |
| CL2017001301A1 (es) | Composiciones oftálmicas estabilizadas de omega 3 | |
| MX2016000405A (es) | Metodos y formulaciones que permiten la modulacion de respuestas inmunitarias relacionadas con la administracion de un farmaco biofarmaceutico. | |
| MY207914A (en) | Semifluorinated alkane compositions comprising omega-3 fatty acid ethyl esters | |
| UY35276A (es) | Nuevos compuestos que inhiben la actividad de Lp-PLA2 | |
| MX2024012898A (es) | Proteinas de fusion de enzimas lisosomales terapeuticas dirigidas, formulaciones asociadas y usos de las mismas | |
| CY1124538T1 (el) | Χρηση prg4 για τη βελτιωση της δυναμικης οπτικης οξυτητας και εκτροπων υψηλοτερης ταξης | |
| BR112017007428A2 (pt) | composições de éster de ácido graxo e ácidos graxos autocomnizantes e suas utilizações no tratamento de estados da doença | |
| MX385698B (es) | Uso de un compuesto que comprende un grupo pirrolidinilo y pirimidinilo para tratar enfermedades oculares | |
| MX2021007161A (es) | Agente que contiene acido ursodesoxicolico para tratar o prevenir la presbicia. | |
| CL2020002519A1 (es) | Composiciones de erenumab y usos de las mismas | |
| EP4364810A3 (en) | Topical formulations and uses thereof | |
| MY194044A (en) | Lipoic acid choline ester compositions and methods to stabilize into pharmaceutically relevant drug products | |
| WO2015048188A3 (en) | Modified fibroblast growth factors for the treatment of ocular disorders | |
| WO2017152129A3 (en) | Treatment of glaucoma and/or retinal diseases and formulations useful therefore |