MX2018008469A - Metodos y dispositivos para tratar trastornos oculares posteriores con aflibercept y otros productos biologicos. - Google Patents
Metodos y dispositivos para tratar trastornos oculares posteriores con aflibercept y otros productos biologicos.Info
- Publication number
- MX2018008469A MX2018008469A MX2018008469A MX2018008469A MX2018008469A MX 2018008469 A MX2018008469 A MX 2018008469A MX 2018008469 A MX2018008469 A MX 2018008469A MX 2018008469 A MX2018008469 A MX 2018008469A MX 2018008469 A MX2018008469 A MX 2018008469A
- Authority
- MX
- Mexico
- Prior art keywords
- devices
- end portion
- methods
- medicament container
- disorderswith
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 229960002833 aflibercept Drugs 0.000 title 1
- 108010081667 aflibercept Proteins 0.000 title 1
- 229960000074 biopharmaceutical Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 5
- 208000000208 Wet Macular Degeneration Diseases 0.000 abstract 3
- 230000008878 coupling Effects 0.000 abstract 1
- 238000010168 coupling process Methods 0.000 abstract 1
- 238000005859 coupling reaction Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Marine Sciences & Fisheries (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
La presente invención se refiere a métodos y dispositivos para tratar la AMD húmeda, CNV, AMD húmeda asociada con CNV y/o AMD húmeda asociada con RVO en un sujeto humano que lo necesite. En ciertos aspectos, los dispositivos que sé proporcionan en la presente incluyen un recipiente de medicamento que define un lumen configurado para contener un medicamento, una porción del extremo distante del recipiente de medicamento que incluye una porción de acoplamiento configurada para acoplarse de manera desmontable a un conjunto de aguja, una porción del extremo próximo del recipiente de medicamento que incluye una pestaña y un hombro longitudinal; un conjunto de pistón que incluye una porción del extremo distante dispuesta de manera móvil dentro del lumen del recipiente de medicamento; y un asa acoplada a una porción del extremo próximo del conjunto de pistón.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662276543P | 2016-01-08 | 2016-01-08 | |
| US201662324708P | 2016-04-19 | 2016-04-19 | |
| PCT/US2017/012757 WO2017120601A1 (en) | 2016-01-08 | 2017-01-09 | Methods and devices for treating posterior ocular disorderswith aflibercept and other biologics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2018008469A true MX2018008469A (es) | 2018-11-09 |
Family
ID=59274052
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018008469A MX2018008469A (es) | 2016-01-08 | 2017-01-09 | Metodos y dispositivos para tratar trastornos oculares posteriores con aflibercept y otros productos biologicos. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP3400014A1 (es) |
| JP (1) | JP2019501200A (es) |
| KR (1) | KR20180101488A (es) |
| CN (1) | CN108778330A (es) |
| AU (1) | AU2017206114A1 (es) |
| BR (1) | BR112018013805A2 (es) |
| CA (1) | CA3010862A1 (es) |
| MX (1) | MX2018008469A (es) |
| WO (1) | WO2017120601A1 (es) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070202186A1 (en) | 2006-02-22 | 2007-08-30 | Iscience Interventional Corporation | Apparatus and formulations for suprachoroidal drug delivery |
| EP2627292B1 (en) | 2010-10-15 | 2018-10-10 | Clearside Biomedical, Inc. | Device for ocular access |
| CN110893188A (zh) | 2012-11-08 | 2020-03-20 | 克莱尔塞德生物医学股份有限公司 | 用于在人类受试者中治疗眼部疾病的方法和装置 |
| CN116327482A (zh) | 2013-05-03 | 2023-06-27 | 科尼尔赛德生物医学公司 | 用于眼部注射的设备和方法 |
| US10188550B2 (en) | 2013-06-03 | 2019-01-29 | Clearside Biomedical, Inc. | Apparatus and methods for drug delivery using multiple reservoirs |
| CN105555311B (zh) | 2013-07-23 | 2021-10-08 | 诺瓦利克有限责任公司 | 稳定的抗体组合物 |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| WO2017055454A1 (en) | 2015-09-30 | 2017-04-06 | Novaliq Gmbh | Semifluorinated compounds and their compositions |
| CN108712911A (zh) | 2015-12-30 | 2018-10-26 | 科达制药股份有限公司 | 抗体及其缀合物 |
| EP3452103A1 (en) | 2016-04-15 | 2019-03-13 | The Trustees Of The University Of Pennsylvania | Compositions for treatment of wet age-related macular degeneration |
| JP2019514581A (ja) | 2016-05-02 | 2019-06-06 | クリアサイド バイオメディカル,インコーポレイテッド | 眼の薬物送達のためのシステムおよび方法 |
| US10973681B2 (en) | 2016-08-12 | 2021-04-13 | Clearside Biomedical, Inc. | Devices and methods for adjusting the insertion depth of a needle for medicament delivery |
| US12090294B2 (en) | 2017-05-02 | 2024-09-17 | Georgia Tech Research Corporation | Targeted drug delivery methods using a microneedle |
| EP3687464A4 (en) * | 2017-09-27 | 2021-09-29 | REGENXBIO Inc. | TREATMENT OF EYE DISEASES WITH A TOTALLY HUMAN POST-TRANSLATION MODIFIED ANTI-VEGF FAB |
| CN111511361A (zh) * | 2017-12-20 | 2020-08-07 | 安杰斯制药公司 | 作为多激酶抑制剂的胺基碳酸盐及尿素化合物 |
| CN108030783A (zh) * | 2017-12-27 | 2018-05-15 | 广东众生药业股份有限公司 | 乐伐替尼在制备防治黄斑变性的药物中的用途 |
| WO2019169341A1 (en) | 2018-03-02 | 2019-09-06 | Kodiak Sciences Inc. | Il-6 antibodies and fusion constructs and conjugates thereof |
| IL318714A (en) * | 2018-05-10 | 2025-03-01 | Regeneron Pharma | Formulations that include high concentrations of VEGF receptor fusion protein |
| CN110693886B (zh) * | 2018-07-09 | 2022-12-06 | 天津医科大学 | 防治脑海绵状血管畸形病变的药物 |
| WO2020127641A1 (fr) * | 2018-12-20 | 2020-06-25 | Laboratoires Thea | Composition ophtalmique nutraceutique pour le traitement de pathologies retiniennes a composante neovasculaire |
| WO2020165132A1 (en) * | 2019-02-13 | 2020-08-20 | Novaliq Gmbh | Compositions and methods for the treatment of ocular neovascularization |
| KR20200101160A (ko) * | 2019-02-19 | 2020-08-27 | 전남대학교산학협력단 | 리보세라닙을 포함하는 안구 신생혈관 억제용 약학 조성물 및 이를 이용한 안구 신생혈관 억제 방법 |
| JP2022521851A (ja) * | 2019-04-03 | 2022-04-12 | レジェンクスバイオ インコーポレーテッド | 眼の病態に対する遺伝子療法 |
| CN110522909B (zh) * | 2019-09-30 | 2024-02-20 | 安徽省立医院 | 一种协同增强抗her2阳性肿瘤效果的药物组合 |
| US11912784B2 (en) | 2019-10-10 | 2024-02-27 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| WO2021093764A1 (en) * | 2019-11-11 | 2021-05-20 | Cstone Pharmaceuticals (Suzhou) Co., Ltd. | Pharmaceutical combination and use thereof |
| WO2021123142A1 (en) * | 2019-12-19 | 2021-06-24 | Active Biotech Ab | Compounds for treatment of eye diseases associated with excessive vascularisation |
| CN115697333A (zh) * | 2020-02-19 | 2023-02-03 | 科尼尔赛德生物医学公司 | 包含阿西替尼的组合物和治疗眼部疾病的方法 |
| EP4164593A1 (en) * | 2020-06-15 | 2023-04-19 | OPKO Pharmaceuticals, LLC | Triamcinolone acetonide-loaded liposomes topical ophthalmic formulations as primary therapy for macular edema secondary to branch retinal vein occlusion |
| WO2022245739A1 (en) * | 2021-05-17 | 2022-11-24 | Regeneron Pharmaceuticals, Inc. | Extended, high dose vegf antagonist regimens for treatment of angiogenic eye disorders |
| CN113546176B (zh) * | 2021-06-30 | 2024-03-15 | 南通大学 | 一种特异性用于抑制眼内血管新生药物合成方法 |
| CN116087525B (zh) * | 2022-11-16 | 2025-10-28 | 东南大学 | 一种即时检测Tau蛋白的微腔结构高灵敏SERS芯片的制备方法 |
| CN118356501A (zh) * | 2023-01-19 | 2024-07-19 | 百奥泰生物制药股份有限公司 | 一种复方制剂及其应用 |
| WO2024167694A2 (en) * | 2023-02-06 | 2024-08-15 | Celularity Inc. | Placental extracellular matrices for ocular delivery of ophthalmic therapeutic agents |
| JP2025003405A (ja) * | 2023-06-23 | 2025-01-09 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | 眼内血管新生性疾患の治療のための、vegfアンタゴニストの延長された高用量レジメン |
| WO2026003803A1 (en) * | 2024-06-28 | 2026-01-02 | Kyowa Kirin Co., Ltd. | Tivozanib for treating posterior segment eye diseases |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014516986A (ja) * | 2011-05-27 | 2014-07-17 | ノバルティス アーゲー | 視覚疾患の治療方法 |
| US20150037422A1 (en) * | 2012-02-22 | 2015-02-05 | Trustees Of Tufts College | Compositions and methods for ocular delivery of a therapeutic agent |
| CN110893188A (zh) * | 2012-11-08 | 2020-03-20 | 克莱尔塞德生物医学股份有限公司 | 用于在人类受试者中治疗眼部疾病的方法和装置 |
| WO2015095772A2 (en) * | 2013-12-20 | 2015-06-25 | Emory University | Formulations and methods for targeted ocular delivery of therapeutic agents |
| EP3157463A4 (en) * | 2014-06-17 | 2018-02-21 | Clearside Biomedical, Inc. | Methods and devices for treating posterior ocular disorders |
-
2017
- 2017-01-09 CN CN201780015406.9A patent/CN108778330A/zh active Pending
- 2017-01-09 MX MX2018008469A patent/MX2018008469A/es unknown
- 2017-01-09 KR KR1020187022893A patent/KR20180101488A/ko not_active Withdrawn
- 2017-01-09 AU AU2017206114A patent/AU2017206114A1/en not_active Abandoned
- 2017-01-09 JP JP2018535400A patent/JP2019501200A/ja active Pending
- 2017-01-09 BR BR112018013805-3A patent/BR112018013805A2/pt not_active Application Discontinuation
- 2017-01-09 WO PCT/US2017/012757 patent/WO2017120601A1/en not_active Ceased
- 2017-01-09 EP EP17736528.5A patent/EP3400014A1/en not_active Withdrawn
- 2017-01-09 CA CA3010862A patent/CA3010862A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20180101488A (ko) | 2018-09-12 |
| BR112018013805A2 (pt) | 2018-12-11 |
| CN108778330A (zh) | 2018-11-09 |
| CA3010862A1 (en) | 2017-07-13 |
| WO2017120601A1 (en) | 2017-07-13 |
| EP3400014A1 (en) | 2018-11-14 |
| AU2017206114A1 (en) | 2018-08-02 |
| JP2019501200A (ja) | 2019-01-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2018008469A (es) | Metodos y dispositivos para tratar trastornos oculares posteriores con aflibercept y otros productos biologicos. | |
| MX2016016836A (es) | Metodos y dispositivos para tratar trastornos oculares posteriores. | |
| PH12014502792A1 (en) | Soft tip cannula | |
| MX2017000920A (es) | Dispositivos magneticos para anastomosis y metodos de entrega. | |
| MX2016016070A (es) | Introductor y guia de cateter con aguja tangencial subretinal. | |
| WO2015164839A3 (en) | System and method for safety syringe | |
| MX2020008980A (es) | Dispositivo de administracion de farmacos. | |
| EP4324414A3 (en) | Devices and methods for treating the skin using a rollerball or a wicking member | |
| WO2014127389A3 (en) | Thrombectomy catheter | |
| NZ630742A (en) | A patient interface | |
| MX2016017028A (es) | Canula de diametro variable y metodos para el control de la profundidad de insercion para administracion de medicamentos. | |
| GB201318950D0 (en) | Deployment Catheter | |
| BR112015017366A2 (pt) | dispositivo médico e método para facilitar a seleção de um implante de anuloplastia | |
| MY182497A (en) | Ocular implant delivery device and method | |
| EP4374873A3 (en) | Methods for treating or preventing opthalmological conditions | |
| MX2020011003A (es) | Valvula para dilatador y ensamble de cubierta. | |
| MX2017001673A (es) | Prenda de compresion medica terapeutica y metodo. | |
| CO6500125A1 (es) | Suministro de curcumina por derivacion | |
| SG10201807789WA (en) | Vaginal composition and use thereof | |
| MX384815B (es) | Dispositivo para insertar una canula de punta roma bajo la piel de un paciente. | |
| WO2017079325A3 (en) | Injection devices and systems and methods for using them | |
| WO2016123496A3 (en) | Suspension implant | |
| MX2015011418A (es) | Tratamiento de enfermedades con nanofibras de poli-n-acetilglucosamina. | |
| IN2014DN07443A (es) | ||
| TN2014000494A1 (en) | Disposable syringe and push rod for the same |