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MX2018007814A - Procedimiento de extraccion de lipopolisacaridos. - Google Patents

Procedimiento de extraccion de lipopolisacaridos.

Info

Publication number
MX2018007814A
MX2018007814A MX2018007814A MX2018007814A MX2018007814A MX 2018007814 A MX2018007814 A MX 2018007814A MX 2018007814 A MX2018007814 A MX 2018007814A MX 2018007814 A MX2018007814 A MX 2018007814A MX 2018007814 A MX2018007814 A MX 2018007814A
Authority
MX
Mexico
Prior art keywords
lps
lipopolisacarids
extraction
procedure
gram
Prior art date
Application number
MX2018007814A
Other languages
English (en)
Inventor
A Kern Jeffrey
Farrenburg Chad
Original Assignee
Glaxosmithkline Biologicals Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biologicals Sa filed Critical Glaxosmithkline Biologicals Sa
Publication of MX2018007814A publication Critical patent/MX2018007814A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0003—General processes for their isolation or fractionation, e.g. purification or extraction from biomass
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/04—Solvent extraction of solutions which are liquid
    • B01D11/0492—Applications, solvents used
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C07H11/04—Phosphates; Phosphites; Polyphosphates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L99/00—Compositions of natural macromolecular compounds or of derivatives thereof not provided for in groups C08L89/00 - C08L97/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Genetics & Genomics (AREA)
  • Sustainable Development (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Extraction Or Liquid Replacement (AREA)

Abstract

Se proporciona un método de extracción de lipopolisacáridos (LPS) de células bacterianas gram negativas, comprendiendo dicho método una etapa de extracción de LPS de la célula bacteriana gram negativa en una solución de extracción de LPS que comprende una sal, agua, un alcohol y un disolvente orgánico adicional. También se proporcionan las composiciones y los usos del LPS extraído.
MX2018007814A 2015-12-22 2016-12-21 Procedimiento de extraccion de lipopolisacaridos. MX2018007814A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562270766P 2015-12-22 2015-12-22
PCT/IB2016/057896 WO2017109733A2 (en) 2015-12-22 2016-12-21 Process

Publications (1)

Publication Number Publication Date
MX2018007814A true MX2018007814A (es) 2018-08-15

Family

ID=57963381

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018007814A MX2018007814A (es) 2015-12-22 2016-12-21 Procedimiento de extraccion de lipopolisacaridos.

Country Status (8)

Country Link
US (1) US11186652B2 (es)
EP (1) EP3394109B1 (es)
JP (1) JP6995045B2 (es)
CN (1) CN108431049B (es)
BR (1) BR112018012791B1 (es)
CA (1) CA3009111A1 (es)
MX (1) MX2018007814A (es)
WO (1) WO2017109733A2 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220372536A1 (en) * 2019-09-24 2022-11-24 Biomedical Research Group Inc. Lipopolysaccharide production method
CN116554361B (zh) * 2023-07-11 2023-11-03 江苏瑞科生物技术股份有限公司 用于提取脂多糖的抽提液和方法
CN116585747B (zh) * 2023-07-12 2023-10-27 江苏瑞科生物技术股份有限公司 一种脂多糖提取装置及提取方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5997881A (en) * 1995-11-22 1999-12-07 University Of Maryland, Baltimore Method of making non-pyrogenic lipopolysaccharide or A
IN185699B (es) * 1996-03-29 2001-04-07 Council Scient Ind Res
US6172220B1 (en) * 1997-01-21 2001-01-09 Board Of Regents Of University Of Nebraska Isolated algal lipopolysaccharides and use of same to inhibit endotoxin-initiated sepsis
JP2001527562A (ja) * 1997-05-16 2001-12-25 メディカル ディフェンス テクノロジーズ エルエルシー リポ多糖コアに対するワクチン
US20030031684A1 (en) * 2001-03-30 2003-02-13 Corixa Corporation Methods for the production of 3-O-deactivated-4'-monophosphoryl lipid a (3D-MLA)
CN102858974A (zh) * 2010-02-18 2013-01-02 明治制果药业株式会社 抗铜绿假单胞菌e血清型脂多糖的抗体
US20130066064A1 (en) * 2010-05-20 2013-03-14 Glaxosmithkline Biologicals S.A, Novel process
CN103013978A (zh) * 2011-09-27 2013-04-03 苏兆明 一种植物rna的提取工艺

Also Published As

Publication number Publication date
CN108431049B (zh) 2021-07-27
US20200102405A1 (en) 2020-04-02
EP3394109A2 (en) 2018-10-31
BR112018012791B1 (pt) 2022-03-29
JP6995045B2 (ja) 2022-02-04
US11186652B2 (en) 2021-11-30
EP3394109C0 (en) 2025-10-29
JP2018538415A (ja) 2018-12-27
WO2017109733A3 (en) 2017-08-24
EP3394109B1 (en) 2025-10-29
WO2017109733A2 (en) 2017-06-29
BR112018012791A2 (en) 2018-12-04
CA3009111A1 (en) 2017-06-29
CN108431049A (zh) 2018-08-21

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