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MX2018007225A - Terapia combinada para el cancer. - Google Patents

Terapia combinada para el cancer.

Info

Publication number
MX2018007225A
MX2018007225A MX2018007225A MX2018007225A MX2018007225A MX 2018007225 A MX2018007225 A MX 2018007225A MX 2018007225 A MX2018007225 A MX 2018007225A MX 2018007225 A MX2018007225 A MX 2018007225A MX 2018007225 A MX2018007225 A MX 2018007225A
Authority
MX
Mexico
Prior art keywords
cancer
combination therapy
patient
compound
formula
Prior art date
Application number
MX2018007225A
Other languages
English (en)
Inventor
Paul BECKMANN Richard
Paul Donoho Gregory
Karis Lin Aimee
WACHECK Volker
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MX2018007225A publication Critical patent/MX2018007225A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • A61K31/497Non-condensed pyrazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención proporciona un método para tratar cánceres histológicos de células escamosas, cáncer de mama, cáncer de próstata, cáncer de vejiga, cáncer cervical, cáncer de endometrio, cáncer de ovario y cáncer colorrectal en un paciente que comprende la administración a un paciente que necesita de dicho tratamiento de una cantidad eficaz de un compuesto de la fórmula (I) o una sal farmacéuticamente aceptable del mismo; en combinación con una cantidad eficaz de un compuesto de la fórmula (II) o una sal farmacéuticamente aceptable del mismo. (ver Fórmulas).
MX2018007225A 2015-12-15 2016-12-08 Terapia combinada para el cancer. MX2018007225A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562267462P 2015-12-15 2015-12-15
PCT/US2016/065503 WO2017105982A1 (en) 2015-12-15 2016-12-08 Combination therapy for cancer

Publications (1)

Publication Number Publication Date
MX2018007225A true MX2018007225A (es) 2018-08-01

Family

ID=57590897

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018007225A MX2018007225A (es) 2015-12-15 2016-12-08 Terapia combinada para el cancer.

Country Status (15)

Country Link
US (1) US20180228795A1 (es)
EP (1) EP3389660B1 (es)
JP (1) JP6359197B2 (es)
KR (1) KR20180081580A (es)
CN (1) CN108472293A (es)
AU (1) AU2016370297A1 (es)
BR (1) BR112018011203A2 (es)
CA (1) CA3005358A1 (es)
EA (1) EA201891005A1 (es)
HK (1) HK1254687A1 (es)
IL (1) IL259097A (es)
MX (1) MX2018007225A (es)
NZ (1) NZ742470A (es)
SG (1) SG11201803903YA (es)
WO (1) WO2017105982A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201402277D0 (en) 2014-02-10 2014-03-26 Sentinel Oncology Ltd Pharmaceutical compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PA8850801A1 (es) * 2008-12-17 2010-07-27 Lilly Co Eli Compuestos útiles para inhibir chk1
RU2627841C2 (ru) * 2010-11-16 2017-08-14 Эррэй Биофарма Инк. Комбинация ингибиторов чекпойнт-киназы 1 и ингибиторов киназы wee 1
JO3003B1 (ar) 2011-01-14 2016-09-05 Lilly Co Eli مركب أيميدازو [4، 5 -c ] كينولين-2- واحد واستخدامه كمثبط كيناز PI3/mtor
US20140314791A1 (en) * 2012-01-05 2014-10-23 Dana-Farber Cancer Institute, Inc. Methods of treating cancer

Also Published As

Publication number Publication date
EP3389660B1 (en) 2019-10-16
BR112018011203A2 (pt) 2018-11-21
CA3005358A1 (en) 2017-06-22
EA201891005A1 (ru) 2018-12-28
NZ742470A (en) 2019-09-27
AU2016370297A1 (en) 2018-05-24
US20180228795A1 (en) 2018-08-16
EP3389660A1 (en) 2018-10-24
CN108472293A (zh) 2018-08-31
HK1254687A1 (zh) 2019-07-26
JP2018502873A (ja) 2018-02-01
IL259097A (en) 2018-06-28
SG11201803903YA (en) 2018-06-28
KR20180081580A (ko) 2018-07-16
WO2017105982A1 (en) 2017-06-22
JP6359197B2 (ja) 2018-07-18

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