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MX2018006299A - Analogos de peptido de la hormona de estimulacion de alfa-melanocito. - Google Patents

Analogos de peptido de la hormona de estimulacion de alfa-melanocito.

Info

Publication number
MX2018006299A
MX2018006299A MX2018006299A MX2018006299A MX2018006299A MX 2018006299 A MX2018006299 A MX 2018006299A MX 2018006299 A MX2018006299 A MX 2018006299A MX 2018006299 A MX2018006299 A MX 2018006299A MX 2018006299 A MX2018006299 A MX 2018006299A
Authority
MX
Mexico
Prior art keywords
peptide analogs
stimulating hormone
alpha
melanocyte stimulating
analogs
Prior art date
Application number
MX2018006299A
Other languages
English (en)
Inventor
Michael A Perricone
John Lyle Dzuris
Timothy E Weeden
James E Stefano
Clark Q Pan
Andrea E Edling
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of MX2018006299A publication Critical patent/MX2018006299A/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/68—Melanocyte-stimulating hormone [MSH]
    • C07K14/685—Alpha-melanotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/68—Melanocyte-stimulating hormone [MSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • A61K38/34—Melanocyte stimulating hormone [MSH], e.g. alpha- or beta-melanotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
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    • C07—ORGANIC CHEMISTRY
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    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
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    • C07K5/10—Tetrapeptides
    • C07K5/1021—Tetrapeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
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    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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Abstract

Se proporcionan en la presente análogos de péptido estables de la hormona de estimulación de alfa-melanocito (a-MSH) nativa que tienen selectividad para el receptor de melanocortina 1 (MC1R). También se proporcionan en la presente preparaciones farmacéuticas de los análogos de péptido de a-MSH, así como métodos para utilizar estos análogos en el tratamiento de condiciones médicas y veterinarias que involucran MC1R.
MX2018006299A 2008-05-27 2010-11-26 Analogos de peptido de la hormona de estimulacion de alfa-melanocito. MX2018006299A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5637308P 2008-05-27 2008-05-27

Publications (1)

Publication Number Publication Date
MX2018006299A true MX2018006299A (es) 2021-11-11

Family

ID=41278142

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2010012990A MX2010012990A (es) 2008-05-27 2009-03-20 Analogos de peptido de la hormona de estimulacion de alfa-melanocito.
MX2013012525A MX356295B (es) 2008-05-27 2009-03-20 Análogos de péptido de la hormona de estimulación de alfa-melanocito.
MX2018006299A MX2018006299A (es) 2008-05-27 2010-11-26 Analogos de peptido de la hormona de estimulacion de alfa-melanocito.

Family Applications Before (2)

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MX2010012990A MX2010012990A (es) 2008-05-27 2009-03-20 Analogos de peptido de la hormona de estimulacion de alfa-melanocito.
MX2013012525A MX356295B (es) 2008-05-27 2009-03-20 Análogos de péptido de la hormona de estimulación de alfa-melanocito.

Country Status (16)

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US (4) US8440793B2 (es)
EP (2) EP2297178B1 (es)
JP (4) JP5624027B2 (es)
KR (4) KR101810110B1 (es)
CN (2) CN107098957A (es)
AU (1) AU2009258054B2 (es)
BR (1) BRPI0912141A2 (es)
CA (2) CA2726076C (es)
DK (2) DK2297178T3 (es)
ES (2) ES2715329T3 (es)
IL (3) IL209369A (es)
MX (3) MX2010012990A (es)
PT (2) PT2297178E (es)
RU (1) RU2496786C2 (es)
TR (1) TR201903610T4 (es)
WO (1) WO2009151708A2 (es)

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MX2010012990A (es) 2008-05-27 2011-05-25 Genzyme Corp Analogos de peptido de la hormona de estimulacion de alfa-melanocito.

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