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MX2018005828A - Compuestos de glucolipidos y sus usos en el tratamiento de tumores. - Google Patents

Compuestos de glucolipidos y sus usos en el tratamiento de tumores.

Info

Publication number
MX2018005828A
MX2018005828A MX2018005828A MX2018005828A MX2018005828A MX 2018005828 A MX2018005828 A MX 2018005828A MX 2018005828 A MX2018005828 A MX 2018005828A MX 2018005828 A MX2018005828 A MX 2018005828A MX 2018005828 A MX2018005828 A MX 2018005828A
Authority
MX
Mexico
Prior art keywords
compounds
glucolipid
tumor treatment
glycolipids
methods
Prior art date
Application number
MX2018005828A
Other languages
English (en)
Other versions
MX392285B (es
Inventor
Vladimirovich Bovin Nicolai
Borisovich Tuzikov Alexander
Henry Stephen
Griffiths Graham
Shaw Stephen
Yurievna Korchagina Elena
Original Assignee
Agalimmune Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agalimmune Ltd filed Critical Agalimmune Ltd
Publication of MX2018005828A publication Critical patent/MX2018005828A/es
Publication of MX392285B publication Critical patent/MX392285B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7032—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C07H5/06—Aminosugars
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)

Abstract

La invención se refiere a compuestos novedosos de glucolípidos y a composiciones farmacéuticas que comprenden dichos glucolípidos y a procedimientos para la preparación de dichos glucolípidos; la invención también se refiere a dichos glucolípidos para uso en el tratamiento de tumores y a métodos de tratamiento de tumores que usan dichos glucolípidos.
MX2018005828A 2015-11-11 2015-11-11 Compuestos de glucolipidos y sus usos en el tratamiento de tumores. MX392285B (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/RU2015/000766 WO2017082753A1 (en) 2015-11-11 2015-11-11 Glycolipid compounds and their uses in the treatment of tumours

Publications (2)

Publication Number Publication Date
MX2018005828A true MX2018005828A (es) 2019-02-20
MX392285B MX392285B (es) 2025-03-24

Family

ID=56117941

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018005828A MX392285B (es) 2015-11-11 2015-11-11 Compuestos de glucolipidos y sus usos en el tratamiento de tumores.

Country Status (13)

Country Link
US (1) US20180344805A1 (es)
EP (1) EP3374367A1 (es)
JP (1) JP6758375B2 (es)
KR (1) KR102517641B1 (es)
CN (1) CN108463466B (es)
AU (1) AU2015414272B2 (es)
BR (1) BR112018009646B1 (es)
CA (1) CA3004107C (es)
HK (1) HK1258843A1 (es)
IL (1) IL259205B (es)
MX (1) MX392285B (es)
RU (1) RU2719486C2 (es)
WO (1) WO2017082753A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2631861A (en) * 2022-04-08 2025-01-15 Kode Biotech Ltd Large scale production of N-acetyllactosamine derivatives
KR20250008358A (ko) * 2023-07-07 2025-01-14 주식회사 고바이오랩 락토바실러스 가세리 균주에서 유래한 당지질

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7820628B2 (en) * 2005-02-22 2010-10-26 University Of Massachusetts Medical School Tumor lesion regression and conversion in situ into autologous tumor vaccines by compositions that result in anti-Gal antibody binding
DK2201025T3 (en) * 2007-10-12 2016-06-27 Kode Biotech Ltd functional lipidkonstruktionsprodukter
JP6322413B2 (ja) 2011-03-10 2018-05-09 プロヴェクタス ファーマテック，インク． 改善されたがん治療のための局所および全身性免疫修飾療法の組み合わせ
SG11201703957VA (en) * 2014-11-21 2017-06-29 Nicolai Vladimirovich Bovin Multivalent ligand-lipid constructs

Also Published As

Publication number Publication date
CA3004107C (en) 2023-10-17
MX392285B (es) 2025-03-24
JP2018533616A (ja) 2018-11-15
IL259205A (en) 2018-07-31
AU2015414272A1 (en) 2018-04-26
RU2719486C2 (ru) 2020-04-17
US20180344805A1 (en) 2018-12-06
KR20180099651A (ko) 2018-09-05
IL259205B (en) 2021-06-30
HK1258843A1 (zh) 2019-11-22
CN108463466A (zh) 2018-08-28
KR102517641B1 (ko) 2023-04-05
RU2018121273A3 (es) 2019-12-13
RU2018121273A (ru) 2019-12-13
BR112018009646B1 (pt) 2020-03-31
CA3004107A1 (en) 2017-05-18
JP6758375B2 (ja) 2020-09-23
EP3374367A1 (en) 2018-09-19
CN108463466B (zh) 2021-07-09
AU2015414272B2 (en) 2021-04-22
WO2017082753A1 (en) 2017-05-18
BR112018009646A2 (en) 2018-12-11

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