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MX2018005625A - Metodo para tratar enfermedades mediante anestesia auricular de los nervios craneales. - Google Patents

Metodo para tratar enfermedades mediante anestesia auricular de los nervios craneales.

Info

Publication number
MX2018005625A
MX2018005625A MX2018005625A MX2018005625A MX2018005625A MX 2018005625 A MX2018005625 A MX 2018005625A MX 2018005625 A MX2018005625 A MX 2018005625A MX 2018005625 A MX2018005625 A MX 2018005625A MX 2018005625 A MX2018005625 A MX 2018005625A
Authority
MX
Mexico
Prior art keywords
cranial nerves
treating disease
anesthesia
auricular anesthesia
auricular
Prior art date
Application number
MX2018005625A
Other languages
English (en)
Other versions
MX390998B (es
Inventor
M Crews Thomas
Original Assignee
M Crews Thomas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by M Crews Thomas filed Critical M Crews Thomas
Publication of MX2018005625A publication Critical patent/MX2018005625A/es
Publication of MX390998B publication Critical patent/MX390998B/es

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0046Ear
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245Amino benzoic acid types, e.g. procaine, novocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • A61K31/41521,2-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. antipyrine, phenylbutazone, sulfinpyrazone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

Métodos para tratar una variedad de enfermedades que comprende emplear anestesia auricular de varios nervios craneales. Se administra una composición farmacéutica en un canal auditivo de un sujeto que necesita de tal tratamiento, la composición incluye un analgésico y/o al menos un anestésico. También se proporcionan las composiciones útiles en los métodos enseñados.
MX2018005625A 2013-05-03 2016-11-02 Metodo para tratar enfermedades mediante anestesia auricular de los nervios craneales. MX390998B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361819023P 2013-05-03 2013-05-03
US14/931,581 US9968589B2 (en) 2013-05-03 2015-11-03 Method of treating disease by auricular anesthesia of cranial nerves
PCT/US2016/060085 WO2017079270A1 (en) 2013-05-03 2016-11-02 Method of treating disease by auricular anesthesia of cranial nerves

Publications (2)

Publication Number Publication Date
MX2018005625A true MX2018005625A (es) 2018-12-06
MX390998B MX390998B (es) 2025-03-21

Family

ID=51844020

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2015015194A MX381106B (es) 2013-05-03 2014-05-05 Metodo de tratamiento de la enfermedad por anestesia auricular de los nervios craneales.
MX2018005625A MX390998B (es) 2013-05-03 2016-11-02 Metodo para tratar enfermedades mediante anestesia auricular de los nervios craneales.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2015015194A MX381106B (es) 2013-05-03 2014-05-05 Metodo de tratamiento de la enfermedad por anestesia auricular de los nervios craneales.

Country Status (17)

Country Link
US (4) US20140357686A1 (es)
EP (2) EP2991620B1 (es)
JP (3) JP6433985B2 (es)
KR (2) KR102086709B1 (es)
CN (2) CN105163718B (es)
AU (2) AU2014262148B2 (es)
CA (2) CA2910422C (es)
DK (1) DK2991620T3 (es)
ES (1) ES2823624T3 (es)
HK (1) HK1212230A1 (es)
IL (2) IL242339B (es)
MX (2) MX381106B (es)
MY (2) MY180310A (es)
RU (2) RU2687249C2 (es)
SG (1) SG11201508509XA (es)
WO (2) WO2014179814A1 (es)
ZA (2) ZA201508782B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2991620B1 (en) * 2013-05-03 2020-07-08 Crews, Thomas, M. Combinations of antipyrine and benzocaine for the treatment of diseases associated with a cranial nerve
WO2016137352A1 (ru) * 2015-02-26 2016-09-01 Общество С Ограниченной Ответственностью "Консорциум-Пик" Фармацевтическая композиция для лечения воспалительных заболеваний уха, способ ее получения и способ лечения указанной композицией
EP3509585B1 (en) 2016-09-07 2023-11-01 Glia, LLC Treatment of symptoms related to neurodegenerative disorders through pharmacological dermal activation of cranial nerves
US20220105052A1 (en) * 2016-12-26 2022-04-07 Cellix Bio Private Limited Compositions and methods for the treatment of chronic pain
CN107789621A (zh) * 2017-12-15 2018-03-13 阜阳市平衡医疗保健器械有限公司 一种治疗头痛的药物及其配制方法
US11607275B2 (en) * 2019-05-20 2023-03-21 Medtronic Ireland Manufacturing Unlimited Company Selection of hypertensive patients for treatment with renal denervation

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DE19524691A1 (de) * 1995-07-06 1997-01-09 Liedtke Pharmed Gmbh Methode und Zusammensetzung einer topischen Therapie von Innenohr und Labyrinth-Symptomen
RU2104056C1 (ru) * 1995-07-10 1998-02-10 Александр Александрович Ланцов Способ лечения периферических поражений лицевого нерва
JPH1094613A (ja) * 1996-08-02 1998-04-14 Mieko Sato 食欲調整用具
US6093417A (en) * 1999-01-11 2000-07-25 Advanced Medical Instruments Composition to treat ear disorders
AU5170400A (en) * 1999-05-27 2000-12-18 George F. El Khoury Topical application of muscarinic and opioid agents for treatment of tinnitus
DE10322497A1 (de) * 2003-05-19 2004-12-09 Liedtke, Rainer K., Dr. Topisch pharmakologische Vorbeugung und Therapie der Hyperakusis
US8940321B2 (en) * 2003-12-12 2015-01-27 Otic Pharma Ltd. Compositions for treatment of ear disorders and methods of use thereof
US8755892B2 (en) * 2007-05-16 2014-06-17 Cardiac Pacemakers, Inc. Systems for stimulating neural targets
WO2011019954A2 (en) * 2009-08-13 2011-02-17 Yehuda Ivri Intracochlear drug delivery to the central nervous system
WO2011028915A2 (en) * 2009-09-03 2011-03-10 University Of Chicago Platelet aggregation inhibitors
US9687387B2 (en) * 2011-03-11 2017-06-27 Yoseph Yaacobi System and methods for treating ear disorders
EP2991620B1 (en) * 2013-05-03 2020-07-08 Crews, Thomas, M. Combinations of antipyrine and benzocaine for the treatment of diseases associated with a cranial nerve

Also Published As

Publication number Publication date
US20220387307A1 (en) 2022-12-08
AU2014262148A1 (en) 2015-11-05
CA3004160A1 (en) 2017-05-11
ZA201508782B (en) 2017-08-30
BR112018008893A8 (pt) 2019-02-26
NZ742076A (en) 2024-12-20
CN108430470A (zh) 2018-08-21
KR20180088408A (ko) 2018-08-03
JP2016522819A (ja) 2016-08-04
CA2910422A1 (en) 2014-11-06
CA2910422C (en) 2022-09-27
MY180310A (en) 2020-11-28
SG11201508509XA (en) 2015-11-27
US9968589B2 (en) 2018-05-15
MX381106B (es) 2025-03-04
AU2016349784A1 (en) 2018-05-17
CN105163718A (zh) 2015-12-16
EP2991620B1 (en) 2020-07-08
JP7512317B2 (ja) 2024-07-08
MX390998B (es) 2025-03-21
US20160051516A1 (en) 2016-02-25
RU2687249C2 (ru) 2019-05-08
BR112018008893A2 (pt) 2018-11-06
ZA201803483B (en) 2019-08-28
IL259019A (en) 2018-06-28
RU2701548C1 (ru) 2019-09-30
WO2017079270A1 (en) 2017-05-11
KR102796310B1 (ko) 2025-04-16
IL259019B (en) 2021-06-30
EP3370716A1 (en) 2018-09-12
EP2991620A1 (en) 2016-03-09
MX2015015194A (es) 2016-02-11
RU2015148757A (ru) 2017-06-08
JP2022065015A (ja) 2022-04-26
IL242339B (en) 2020-05-31
CA3004160C (en) 2023-03-14
WO2014179814A1 (en) 2014-11-06
JP6433985B2 (ja) 2018-12-05
EP2991620A4 (en) 2017-01-11
US20140357686A1 (en) 2014-12-04
US20180360745A1 (en) 2018-12-20
HK1212230A1 (en) 2016-06-10
DK2991620T3 (da) 2020-10-12
EP3370716A4 (en) 2019-04-17
KR102086709B1 (ko) 2020-03-09
ES2823624T3 (es) 2021-05-07
KR20160003012A (ko) 2016-01-08
US11123284B2 (en) 2021-09-21
AU2014262148B2 (en) 2018-11-22
JP2018536709A (ja) 2018-12-13
CN105163718B (zh) 2020-03-17
MY196979A (en) 2023-05-16
AU2016349784B2 (en) 2019-06-06
NZ713746A (en) 2021-01-29

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