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MX2018001739A - Receptores de antígenos quiméricos basados en anticuerpos de dominio simple y métodos de uso de estos. - Google Patents

Receptores de antígenos quiméricos basados en anticuerpos de dominio simple y métodos de uso de estos.

Info

Publication number
MX2018001739A
MX2018001739A MX2018001739A MX2018001739A MX2018001739A MX 2018001739 A MX2018001739 A MX 2018001739A MX 2018001739 A MX2018001739 A MX 2018001739A MX 2018001739 A MX2018001739 A MX 2018001739A MX 2018001739 A MX2018001739 A MX 2018001739A
Authority
MX
Mexico
Prior art keywords
methods
domain antibodies
receivers
antigens based
simple domain
Prior art date
Application number
MX2018001739A
Other languages
English (en)
Inventor
Chuan-Chu Chou
Lin Wang
Fan Xiaohu
Wang Pingyan
Yang Lei
Zhuang Qiuchuan
Hao Jiaying
Original Assignee
Legend Biotech Ireland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Legend Biotech Ireland Ltd filed Critical Legend Biotech Ireland Ltd
Publication of MX2018001739A publication Critical patent/MX2018001739A/es

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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • A61K39/0011—Cancer antigens
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Abstract

La presente solicitud proporciona anticuerpos de dominio simple, y receptores de antígenos quiméricos que comprenden uno o más dominios de unión al antígeno, cada uno de los cuales comprende un anticuerpo de dominio simple. También se proporcionan células efectoras inmunitarias modificadas genéticamente (tales como linfocitos T) que comprenden los receptores de antígenos quiméricos. También se proporcionan composiciones farmacéuticas, kits y métodos para tratar el cáncer.
MX2018001739A 2015-08-11 2016-08-10 Receptores de antígenos quiméricos basados en anticuerpos de dominio simple y métodos de uso de estos. MX2018001739A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201510490002 2015-08-11
CN201510733585.2A CN105384825B (zh) 2015-08-11 2015-11-02 一种基于单域抗体的双特异性嵌合抗原受体及其应用
PCT/CN2016/094408 WO2017025038A1 (en) 2015-08-11 2016-08-10 Chimeric antigen receptors based on single-domain antibodies and methods of use thereof

Publications (1)

Publication Number Publication Date
MX2018001739A true MX2018001739A (es) 2018-08-15

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