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MX2018000743A - Granulos de manitol para compresion directa. - Google Patents

Granulos de manitol para compresion directa.

Info

Publication number
MX2018000743A
MX2018000743A MX2018000743A MX2018000743A MX2018000743A MX 2018000743 A MX2018000743 A MX 2018000743A MX 2018000743 A MX2018000743 A MX 2018000743A MX 2018000743 A MX2018000743 A MX 2018000743A MX 2018000743 A MX2018000743 A MX 2018000743A
Authority
MX
Mexico
Prior art keywords
granules
direct compression
present
manitol
relates
Prior art date
Application number
MX2018000743A
Other languages
English (en)
Other versions
MX389438B (es
Inventor
Lefevre Philippe
Boit Baptiste
Original Assignee
Roquette Freres
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roquette Freres filed Critical Roquette Freres
Publication of MX2018000743A publication Critical patent/MX2018000743A/es
Publication of MX389438B publication Critical patent/MX389438B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a los gránulos de manitol que se utilizan para la preparación de comprimidos mediante compresión directa, los cuales no requieren una pequeña cantidad de lubricante con el fin de ser procesados. La presente invención también se refiere a un proceso para preparar dichos gránulos. La presente invención también engloba las composiciones pulverulentas que comprenden estos gránulos, y también los procesos de compresión directa que utilizan estas composiciones pulverulentas. Por último, la presente invención se refiere a los comprimidos compuestos por estas composiciones pulverulentas.
MX2018000743A 2015-07-17 2016-07-15 Granulos de manitol para compresion directa. MX389438B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1556787A FR3038836B1 (fr) 2015-07-17 2015-07-17 Granules de mannitol pour compression directe
PCT/FR2016/051820 WO2017013338A1 (fr) 2015-07-17 2016-07-15 Granules de mannitol pour compression directe

Publications (2)

Publication Number Publication Date
MX2018000743A true MX2018000743A (es) 2018-08-15
MX389438B MX389438B (es) 2025-03-19

Family

ID=54478163

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018000743A MX389438B (es) 2015-07-17 2016-07-15 Granulos de manitol para compresion directa.

Country Status (12)

Country Link
US (1) US10828256B2 (es)
EP (1) EP3324943B1 (es)
JP (2) JP6941596B2 (es)
KR (1) KR102631002B1 (es)
CN (1) CN109348704B (es)
AU (1) AU2016295192B2 (es)
CA (1) CA2991739C (es)
ES (1) ES2885866T3 (es)
FR (1) FR3038836B1 (es)
MX (1) MX389438B (es)
PL (1) PL3324943T3 (es)
WO (1) WO2017013338A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT201900002859A1 (it) * 2019-02-27 2020-08-27 Ntc S R L Composizione e contenitore, kit, metodo d'uso
IT201900002857A1 (it) * 2019-02-27 2020-08-27 Ntc S R L Procedimento di riempimento di contenitori con una polvere
CN110172012A (zh) * 2019-07-06 2019-08-27 浙江华康药业股份有限公司 直接压片甘露醇的制备方法
CN110787722A (zh) * 2019-12-01 2020-02-14 浙江华康药业股份有限公司 一种结晶甘露醇干法造粒装置及工艺
EP4475821A1 (fr) * 2022-02-08 2024-12-18 Roquette Freres Granules de mannitol directement comprimables
FR3132522B1 (fr) * 2022-02-08 2025-04-04 Roquette Freres Granules de mannitol directement comprimable
CN117860688B (zh) * 2024-03-12 2024-05-31 山东天力药业有限公司 一种直压级甘露醇颗粒及其制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2571046B1 (fr) 1984-10-03 1987-10-16 Roquette Freres Procede de preparation de mannitol granulaire directement compressible
FR2571045B1 (fr) 1984-10-03 1987-12-11 Roquette Freres Mannitol granulaire directement compressible et son procede de fabrication
FR2710637B1 (fr) * 1993-09-28 1995-12-08 Roquette Freres Mannitol pulvérulent de friabilité modérée et son procédé de préparation.
DE10161402A1 (de) * 2001-12-13 2003-06-18 Merck Patent Gmbh Verfahren zur Herstellung von direkt tablettierbarem beta-Mannit
US7118765B2 (en) * 2001-12-17 2006-10-10 Spi Pharma, Inc. Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms
JPWO2003103713A1 (ja) 2002-06-10 2005-10-06 大日本製薬株式会社 速崩壊性錠剤及びその製造方法
JP2004175768A (ja) * 2002-11-29 2004-06-24 Towa Yakuhin Kk 安定なオメプラゾール腸溶錠の製造法
US8895141B2 (en) 2008-08-18 2014-11-25 Mitsubishi Shoji Foodtech Co., Ltd. Excipient for compressed tablets comprising novel spherical mannitol
JP2010070466A (ja) * 2008-09-16 2010-04-02 Kyoto Pharmaceutical Industries Ltd 口腔内崩壊錠
FR2944971B1 (fr) * 2009-04-30 2012-09-07 Roquette Freres Coagglomerats de mannitol et d'amidon granulaire comprimables et a ecoulement libre
JP2012180280A (ja) 2009-05-28 2012-09-20 Daiichi Sankyo Co Ltd 貯蔵安定性が改善された固形製剤
US9918938B2 (en) * 2013-09-30 2018-03-20 Daiichi Sankyo Company, Limited Selective production method for D-mannitol α-form crystal using spray-drying method
CN104721188A (zh) 2013-12-20 2015-06-24 中美华世通生物医药科技（武汉）有限公司 一种稳定的含苯甲酸阿格列汀的组合物

Also Published As

Publication number Publication date
EP3324943B1 (fr) 2021-06-23
CA2991739A1 (fr) 2017-01-26
CA2991739C (fr) 2025-06-10
CN109348704B (zh) 2022-04-19
JP7198860B2 (ja) 2023-01-04
US10828256B2 (en) 2020-11-10
MX389438B (es) 2025-03-19
KR102631002B1 (ko) 2024-01-30
FR3038836B1 (fr) 2017-07-14
EP3324943A1 (fr) 2018-05-30
ES2885866T3 (es) 2021-12-15
JP2021105035A (ja) 2021-07-26
JP2018520192A (ja) 2018-07-26
AU2016295192A1 (en) 2018-03-01
CN109348704A (zh) 2019-02-15
PL3324943T3 (pl) 2021-11-15
US20200085746A1 (en) 2020-03-19
KR20180029035A (ko) 2018-03-19
FR3038836A1 (fr) 2017-01-20
JP6941596B2 (ja) 2021-09-29
WO2017013338A1 (fr) 2017-01-26
AU2016295192B2 (en) 2021-09-09

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