MX2017016991A - Formulación para la administración oral de extracto de arándano azul como auxiliar en la conservación de la salud de la película lagrimal en seres humanos. - Google Patents
Formulación para la administración oral de extracto de arándano azul como auxiliar en la conservación de la salud de la película lagrimal en seres humanos.Info
- Publication number
- MX2017016991A MX2017016991A MX2017016991A MX2017016991A MX2017016991A MX 2017016991 A MX2017016991 A MX 2017016991A MX 2017016991 A MX2017016991 A MX 2017016991A MX 2017016991 A MX2017016991 A MX 2017016991A MX 2017016991 A MX2017016991 A MX 2017016991A
- Authority
- MX
- Mexico
- Prior art keywords
- vitamin
- preserving
- health
- formulation
- coadjuvant
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title abstract 6
- 239000000203 mixture Substances 0.000 title abstract 6
- 229940055416 blueberry extract Drugs 0.000 title abstract 3
- 235000019216 blueberry extract Nutrition 0.000 title abstract 3
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 abstract 6
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 abstract 3
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 abstract 3
- 229930003427 Vitamin E Natural products 0.000 abstract 3
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 abstract 3
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 abstract 3
- 235000020673 eicosapentaenoic acid Nutrition 0.000 abstract 3
- 229960005135 eicosapentaenoic acid Drugs 0.000 abstract 3
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 abstract 3
- 235000021323 fish oil Nutrition 0.000 abstract 3
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 abstract 3
- 235000019155 vitamin A Nutrition 0.000 abstract 3
- 239000011719 vitamin A Substances 0.000 abstract 3
- 235000019165 vitamin E Nutrition 0.000 abstract 3
- 229940046009 vitamin E Drugs 0.000 abstract 3
- 239000011709 vitamin E Substances 0.000 abstract 3
- 229940045997 vitamin a Drugs 0.000 abstract 3
- 102000010445 Lactoferrin Human genes 0.000 abstract 2
- 108010063045 Lactoferrin Proteins 0.000 abstract 2
- MBMBGCFOFBJSGT-KUBAVDMBSA-N all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 abstract 2
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 2
- 235000020669 docosahexaenoic acid Nutrition 0.000 abstract 2
- CSSYQJWUGATIHM-IKGCZBKSSA-N l-phenylalanyl-l-lysyl-l-cysteinyl-l-arginyl-l-arginyl-l-tryptophyl-l-glutaminyl-l-tryptophyl-l-arginyl-l-methionyl-l-lysyl-l-lysyl-l-leucylglycyl-l-alanyl-l-prolyl-l-seryl-l-isoleucyl-l-threonyl-l-cysteinyl-l-valyl-l-arginyl-l-arginyl-l-alanyl-l-phenylal Chemical compound C([C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CC=CC=C1 CSSYQJWUGATIHM-IKGCZBKSSA-N 0.000 abstract 2
- 235000021242 lactoferrin Nutrition 0.000 abstract 2
- 229940078795 lactoferrin Drugs 0.000 abstract 2
- 235000020660 omega-3 fatty acid Nutrition 0.000 abstract 2
- DVSZKTAMJJTWFG-SKCDLICFSA-N (2e,4e,6e,8e,10e,12e)-docosa-2,4,6,8,10,12-hexaenoic acid Chemical compound CCCCCCCCC\C=C\C=C\C=C\C=C\C=C\C=C\C(O)=O DVSZKTAMJJTWFG-SKCDLICFSA-N 0.000 abstract 1
- GZJLLYHBALOKEX-UHFFFAOYSA-N 6-Ketone, O18-Me-Ussuriedine Natural products CC=CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O GZJLLYHBALOKEX-UHFFFAOYSA-N 0.000 abstract 1
- 101000798114 Homo sapiens Lactotransferrin Proteins 0.000 abstract 1
- 244000078534 Vaccinium myrtillus Species 0.000 abstract 1
- 235000017537 Vaccinium myrtillus Nutrition 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 239000004599 antimicrobial Substances 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 230000003078 antioxidant effect Effects 0.000 abstract 1
- 235000006708 antioxidants Nutrition 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940090949 docosahexaenoic acid Drugs 0.000 abstract 1
- KAUVQQXNCKESLC-UHFFFAOYSA-N docosahexaenoic acid (DHA) Natural products COC(=O)C(C)NOCC1=CC=CC=C1 KAUVQQXNCKESLC-UHFFFAOYSA-N 0.000 abstract 1
- 102000050459 human LTF Human genes 0.000 abstract 1
- 239000002417 nutraceutical Substances 0.000 abstract 1
- 235000021436 nutraceutical agent Nutrition 0.000 abstract 1
- -1 omega-6 Chemical compound 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/19—Dairy proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A23L33/12—Fatty acids or derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
- A23L33/155—Vitamins A or D
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/45—Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/40—Transferrins, e.g. lactoferrins, ovotransferrins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Botany (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Alternative & Traditional Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
Se presenta como invención una formulación nutracéutica para el consumo de extracto de arándano azul, aceite de pescado (Omega-3 y Omega-6), Lactoferrina humana recombinante, Vitamina A y Vitamina E por el ser humano vía oral. La invención se encuentra dentro del campo de la oftalmología y ha sido desarrollada como un coadyuvante para preservar la salud de la película lagrimal y de la superficie ocular. Esta formulación contiene un extracto de origen natural (Vaccinium myrtillus L) el cual tiene propiedades antioxidantes y antinflamatorias, además hace uso del Ácido eicosapentaenoico (EPA) omega 6 y del Ácido docosahexaenoico (DHA) omega 3 que se obtiene del aceite del pescado que, en conjunto con la lactoferrina, la vitamina A y vitamina E se logra una mejoría en la calidad de la lágrima al tener estos compuestos efectos antimicrobiales y antiinflamatorios. Esta formulación ha sido diseñada para coadyuvar en la salud de la película lagrimal. En el arte previamente descrito no existe una formulación para la administración oral de extracto de arándano azul en conjunto con lactoferrina, así como su combinación con vitamina A, vitamina E y aceite de pescado (ácido eicosapentanoico y ácido docohexaenoico) ni para su uso como adyuvante para la salud de la película lagrimal y/o de la superficie ocular.
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2017016991A MX2017016991A (es) | 2017-12-20 | 2017-12-20 | Formulación para la administración oral de extracto de arándano azul como auxiliar en la conservación de la salud de la película lagrimal en seres humanos. |
| CN201880088073.7A CN111712237A (zh) | 2017-12-20 | 2018-12-18 | 蓝莓提取物作为用于保持人体角膜前膜健康的辅助剂的口服施用制剂 |
| CA3102251A CA3102251A1 (en) | 2017-12-20 | 2018-12-18 | Oral administration formulation of blueberry extract as a coadjuvant for preserving the health of human precorneal film |
| ES18891919T ES2962253T3 (es) | 2017-12-20 | 2018-12-18 | Formulación para la administración oral de extracto del arándano azul como coadyuvante en la conservación de la salud de la película precorneal humana |
| EP18891919.5A EP3730130B1 (en) | 2017-12-20 | 2018-12-18 | Oral administration formulation of blueberry extract as a coadjuvant for preserving the health of human precorneal film |
| PCT/MX2018/000154 WO2019125127A1 (es) | 2017-12-20 | 2018-12-18 | Formulación para la administración oral de extracto del arándano azul como auxiliar en la conservación de la salud de la película lagrimal en seres humanos |
| JP2020555757A JP2021508502A (ja) | 2017-12-20 | 2018-12-18 | ヒト前角膜の健康維持のための補助剤としてのブルーベリー抽出物の経口投与配合物 |
| US16/954,401 US11937625B2 (en) | 2017-12-20 | 2018-12-18 | Oral administration formulation of blueberry extract as a coadjuvant for preserving the health of human precorneal film |
| BR112020012073-1A BR112020012073A2 (pt) | 2017-12-20 | 2018-12-18 | formulação de um suplemento alimentar |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2017016991A MX2017016991A (es) | 2017-12-20 | 2017-12-20 | Formulación para la administración oral de extracto de arándano azul como auxiliar en la conservación de la salud de la película lagrimal en seres humanos. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2017016991A true MX2017016991A (es) | 2019-06-21 |
Family
ID=66994110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017016991A MX2017016991A (es) | 2017-12-20 | 2017-12-20 | Formulación para la administración oral de extracto de arándano azul como auxiliar en la conservación de la salud de la película lagrimal en seres humanos. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US11937625B2 (es) |
| EP (1) | EP3730130B1 (es) |
| JP (1) | JP2021508502A (es) |
| CN (1) | CN111712237A (es) |
| BR (1) | BR112020012073A2 (es) |
| CA (1) | CA3102251A1 (es) |
| ES (1) | ES2962253T3 (es) |
| MX (1) | MX2017016991A (es) |
| WO (1) | WO2019125127A1 (es) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4635487A1 (en) | 2022-12-13 | 2025-10-22 | Centro de Retina Médica Y Quirúrgica, S.C. | Uses of an orally administered formulation containing anthocyanins and pterostilbenes from blueberry extract, omega-3 fatty acids, lactoferrin, vitamins a and e and excipients with surfactant properties, for primary treatment and/or as an adjuvant for dry eye syndrome in human beings |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3702031A1 (de) * | 1987-01-24 | 1988-08-04 | Basf Ag | Verfahren zur herstellung von mikrodispersen fischoelpraeparaten |
| FR2712823B1 (fr) * | 1993-11-25 | 1996-02-23 | Scherer Sa Rp | Capsule molle de gélatine renfermant un mélange à forte teneur en eau. |
| DK1014969T3 (da) * | 1997-09-09 | 2009-03-16 | Univ Rutgers | Plante-proanthocyanidin-ekstrakt, der er effektiv til inhibering af adhærens af bakterier med P-type fimbriae til overflader |
| US5955102A (en) * | 1998-09-04 | 1999-09-21 | Amway Corporation | Softgel capsule containing DHA and antioxidants |
| US6506412B2 (en) | 2000-11-29 | 2003-01-14 | Sciencebased Health | Treatment of dry eye syndrome |
| US20060127505A1 (en) * | 2002-01-16 | 2006-06-15 | David Haines | Anti-inflammatory formulations |
| US7029712B1 (en) * | 2002-07-17 | 2006-04-18 | Biosyntrx Inc | Treatment for dry eye syndrome |
| AU2003259145A1 (en) | 2002-07-17 | 2004-02-02 | Spencer P. Thornton | Treatment for dry eye syndrome |
| FR2856304B1 (fr) * | 2003-06-20 | 2006-03-03 | Natural Product Consulting | Composition pour la prevention des infections du systeme urinaire |
| SE528337C2 (sv) * | 2004-06-23 | 2006-10-24 | Nestor Medical Ab | Sammansättning innefattande mjölksyra och laktoferrin, eller ett peptidfragment därav, och användning av denna sammansättning för behandling av tillstånd i urogenitalsystemet |
| US7638142B2 (en) * | 2005-10-12 | 2009-12-29 | Vitamin Science, Inc. | Therapeutic composition for the treatment of dry eye syndrome |
| ITRM20060435A1 (it) * | 2006-08-09 | 2008-02-10 | Opocrin Spa | Composizione a base di mirtillo rosso vaccinium mcrocarpon e lattoferrina per la prevenzione e il trattamento delle infezioni del tratto urinario |
| JP5106809B2 (ja) * | 2006-08-15 | 2012-12-26 | 株式会社Ｎｒｌファーマ | ラクトフェリンを含有する医薬組成物ならびに加工食品 |
| CA2717699A1 (en) * | 2008-03-14 | 2009-09-17 | Nrl Pharma, Inc. | Polyethylene glycolated lactoferrin complex and method of producing the same |
| JP2009221162A (ja) * | 2008-03-17 | 2009-10-01 | Yokohama Tlo Co Ltd | ラクトフェリンを有効成分とするｕｃｐ発現促進剤 |
| CN101731597B (zh) * | 2008-11-05 | 2013-11-20 | 康魄商贸(上海)有限公司 | 蓝莓鱼油胶囊 |
| JP2011051903A (ja) * | 2009-08-31 | 2011-03-17 | Nrl Pharma Inc | ラクトフェリン徐放製剤の製造法 |
| US20110280851A1 (en) * | 2010-05-12 | 2011-11-17 | Herzlinger Alexander S | Compositions Comprising Cranberry Extract and Methods of Use Thereof |
| CN102379446B (zh) | 2011-11-03 | 2013-06-19 | 南昌大学 | 一种护目健眼饮料及其制备方法 |
| JP6336373B2 (ja) * | 2014-10-08 | 2018-06-06 | 株式会社えがお | マリーゴールド抽出物を含有する加工食品 |
| CN105029443A (zh) | 2015-07-06 | 2015-11-11 | 哈尔滨瑞康源生物科技有限公司 | 一种预防眼病、缓解视疲劳的营养食品及其制备方法 |
-
2017
- 2017-12-20 MX MX2017016991A patent/MX2017016991A/es unknown
-
2018
- 2018-12-18 CN CN201880088073.7A patent/CN111712237A/zh active Pending
- 2018-12-18 EP EP18891919.5A patent/EP3730130B1/en active Active
- 2018-12-18 CA CA3102251A patent/CA3102251A1/en active Pending
- 2018-12-18 WO PCT/MX2018/000154 patent/WO2019125127A1/es not_active Ceased
- 2018-12-18 US US16/954,401 patent/US11937625B2/en active Active
- 2018-12-18 ES ES18891919T patent/ES2962253T3/es active Active
- 2018-12-18 BR BR112020012073-1A patent/BR112020012073A2/pt unknown
- 2018-12-18 JP JP2020555757A patent/JP2021508502A/ja active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4635487A1 (en) | 2022-12-13 | 2025-10-22 | Centro de Retina Médica Y Quirúrgica, S.C. | Uses of an orally administered formulation containing anthocyanins and pterostilbenes from blueberry extract, omega-3 fatty acids, lactoferrin, vitamins a and e and excipients with surfactant properties, for primary treatment and/or as an adjuvant for dry eye syndrome in human beings |
Also Published As
| Publication number | Publication date |
|---|---|
| CN111712237A (zh) | 2020-09-25 |
| US20210076726A1 (en) | 2021-03-18 |
| US11937625B2 (en) | 2024-03-26 |
| WO2019125127A1 (es) | 2019-06-27 |
| EP3730130B1 (en) | 2023-08-16 |
| JP2021508502A (ja) | 2021-03-11 |
| EP3730130C0 (en) | 2023-08-16 |
| CA3102251A1 (en) | 2019-06-27 |
| EP3730130A4 (en) | 2021-09-15 |
| EP3730130A1 (en) | 2020-10-28 |
| BR112020012073A2 (pt) | 2020-11-24 |
| ES2962253T3 (es) | 2024-03-18 |
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