MX2017014740A - Métodos de tratamiento del cáncer con anticuerpos anti-ox40. - Google Patents
Métodos de tratamiento del cáncer con anticuerpos anti-ox40.Info
- Publication number
- MX2017014740A MX2017014740A MX2017014740A MX2017014740A MX2017014740A MX 2017014740 A MX2017014740 A MX 2017014740A MX 2017014740 A MX2017014740 A MX 2017014740A MX 2017014740 A MX2017014740 A MX 2017014740A MX 2017014740 A MX2017014740 A MX 2017014740A
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- antibodies
- methods
- treating cancer
- individual
- antibody
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- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 201000011510 cancer Diseases 0.000 title abstract 2
- 102100022153 Tumor necrosis factor receptor superfamily member 4 Human genes 0.000 abstract 1
- 101710165473 Tumor necrosis factor receptor superfamily member 4 Proteins 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
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- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- C12Q2600/00—Oligonucleotides characterized by their use
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- General Health & Medical Sciences (AREA)
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- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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Abstract
La invención proporciona métodos para tratar o retrasar el progreso de cáncer en un individuo, que comprende administrar al individuo un anticuerpo de agonista OX40. En algunas modalidades, el anticuerpo es administrado en una dosis seleccionada de aproximadamente 0.2mg, aproximadamente 0.8mg, aproximadamente 3.2mg, aproximadamente 12mg, aproximadamente 40mg, aproximadamente 80mg, aproximadamente 130mg, aproximadamente 160mg, aproximadamente 300mg, aproximadamente 320mg, aproximadamente 400mg, aproximadamente 600mg y aproximadamente 12000mg.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562172802P | 2015-06-08 | 2015-06-08 | |
| US201562173339P | 2015-06-09 | 2015-06-09 | |
| US201662308745P | 2016-03-15 | 2016-03-15 | |
| US201662321686P | 2016-04-12 | 2016-04-12 | |
| PCT/US2016/036257 WO2016200836A1 (en) | 2015-06-08 | 2016-06-07 | Methods of treating cancer using anti-ox40 antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2017014740A true MX2017014740A (es) | 2018-08-15 |
Family
ID=56203968
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017014740A MX2017014740A (es) | 2015-06-08 | 2016-06-07 | Métodos de tratamiento del cáncer con anticuerpos anti-ox40. |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20160355597A1 (es) |
| EP (1) | EP3303399A1 (es) |
| JP (1) | JP2018521019A (es) |
| KR (1) | KR20180011839A (es) |
| CN (1) | CN107810011A (es) |
| AU (1) | AU2016274585A1 (es) |
| CA (1) | CA2985483A1 (es) |
| HK (1) | HK1252272A1 (es) |
| IL (1) | IL255569A (es) |
| MX (1) | MX2017014740A (es) |
| WO (1) | WO2016200836A1 (es) |
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| US10034939B2 (en) * | 2012-10-26 | 2018-07-31 | The University Of Chicago | Synergistic combination of immunologic inhibitors for the treatment of cancer |
| WO2015153514A1 (en) | 2014-03-31 | 2015-10-08 | Genentech, Inc. | Combination therapy comprising anti-angiogenesis agents and ox40 binding agonists |
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| CN114381521A (zh) | 2014-11-03 | 2022-04-22 | 豪夫迈·罗氏有限公司 | 用于ox40激动剂治疗的功效预测和评估的方法和生物标志物 |
| CN115594765A (zh) | 2015-10-02 | 2023-01-13 | 豪夫迈·罗氏有限公司(Ch) | 对共刺激性tnf受体特异性的双特异性抗体 |
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| CN108623686A (zh) * | 2017-03-25 | 2018-10-09 | 信达生物制药(苏州)有限公司 | 抗ox40抗体及其用途 |
| EP3704159A1 (en) | 2017-11-01 | 2020-09-09 | Bristol-Myers Squibb Company | Immunostimulatory agonistic antibodies for use in treating cancer |
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| WO2020243563A1 (en) | 2019-05-30 | 2020-12-03 | Bristol-Myers Squibb Company | Multi-tumor gene signatures for suitability to immuno-oncology therapy |
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-
2016
- 2016-06-07 HK HK18111584.9A patent/HK1252272A1/zh unknown
- 2016-06-07 CA CA2985483A patent/CA2985483A1/en not_active Abandoned
- 2016-06-07 US US15/176,100 patent/US20160355597A1/en not_active Abandoned
- 2016-06-07 KR KR1020187000011A patent/KR20180011839A/ko not_active Withdrawn
- 2016-06-07 WO PCT/US2016/036257 patent/WO2016200836A1/en not_active Ceased
- 2016-06-07 AU AU2016274585A patent/AU2016274585A1/en not_active Abandoned
- 2016-06-07 EP EP16732086.0A patent/EP3303399A1/en not_active Withdrawn
- 2016-06-07 CN CN201680025583.0A patent/CN107810011A/zh active Pending
- 2016-06-07 MX MX2017014740A patent/MX2017014740A/es unknown
- 2016-06-07 JP JP2017563158A patent/JP2018521019A/ja active Pending
-
2017
- 2017-11-09 IL IL255569A patent/IL255569A/en unknown
-
2018
- 2018-05-11 US US15/977,671 patent/US20180346586A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20160355597A1 (en) | 2016-12-08 |
| US20180346586A1 (en) | 2018-12-06 |
| CN107810011A (zh) | 2018-03-16 |
| IL255569A (en) | 2018-01-31 |
| HK1252272A1 (zh) | 2019-05-24 |
| CA2985483A1 (en) | 2016-12-15 |
| WO2016200836A1 (en) | 2016-12-15 |
| EP3303399A1 (en) | 2018-04-11 |
| KR20180011839A (ko) | 2018-02-02 |
| AU2016274585A1 (en) | 2017-12-14 |
| JP2018521019A (ja) | 2018-08-02 |
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