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MX2017012021A - Compuestos antifungicos y procesos para la fabricacion. - Google Patents

Compuestos antifungicos y procesos para la fabricacion.

Info

Publication number
MX2017012021A
MX2017012021A MX2017012021A MX2017012021A MX2017012021A MX 2017012021 A MX2017012021 A MX 2017012021A MX 2017012021 A MX2017012021 A MX 2017012021A MX 2017012021 A MX2017012021 A MX 2017012021A MX 2017012021 A MX2017012021 A MX 2017012021A
Authority
MX
Mexico
Prior art keywords
antifungic
compounds
manufacturing processes
compound
polymorphs
Prior art date
Application number
MX2017012021A
Other languages
English (en)
Other versions
MX381344B (es
Inventor
J Hoekstra William
Bonnaud Thierry
Dale Wirth David
EHIWE Tracy
Original Assignee
Viamet Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viamet Pharmaceuticals Inc filed Critical Viamet Pharmaceuticals Inc
Publication of MX2017012021A publication Critical patent/MX2017012021A/es
Publication of MX381344B publication Critical patent/MX381344B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B63/00—Purification; Separation; Stabilisation; Use of additives
    • C07B63/04—Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epidemiology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

La presente invención se refiere a formas polimórficas del compuesto 1 o 1a y procesos para preparar polimorfos del Compuesto 1 y 1a, que son útiles como agentes antifúngicos. En particular, la invención trata de proporcionar una nueva metodología para la preparación de polimorfos del compuesto 1 y derivados sustituidos de los mismos.
MX2017012021A 2015-03-19 2016-03-17 Compuestos antifungicos y procesos para la fabricacion. MX381344B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562135682P 2015-03-19 2015-03-19
PCT/US2016/022858 WO2016149486A1 (en) 2015-03-19 2016-03-17 Antifungal compounds and processes for making

Publications (2)

Publication Number Publication Date
MX2017012021A true MX2017012021A (es) 2018-01-30
MX381344B MX381344B (es) 2025-03-12

Family

ID=56919372

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017012021A MX381344B (es) 2015-03-19 2016-03-17 Compuestos antifungicos y procesos para la fabricacion.

Country Status (19)

Country Link
US (4) US9840492B2 (es)
EP (1) EP3271347B1 (es)
KR (1) KR102603277B1 (es)
CN (1) CN107428724B (es)
AU (1) AU2016233113B2 (es)
BR (1) BR112017018823A2 (es)
CA (1) CA2978339C (es)
DK (1) DK3271347T3 (es)
EA (1) EA037556B1 (es)
ES (1) ES2926063T3 (es)
HR (1) HRP20221113T1 (es)
HU (1) HUE059771T2 (es)
LT (1) LT3271347T (es)
MX (1) MX381344B (es)
PL (1) PL3271347T3 (es)
PT (1) PT3271347T (es)
RS (1) RS63566B1 (es)
SI (1) SI3271347T1 (es)
WO (1) WO2016149486A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3351541A1 (en) 2011-12-11 2018-07-25 Viamet Pharmaceuticals (NC), Inc. Metalloenzyme inhibitor compounds
AU2015231220B2 (en) 2014-03-19 2019-04-04 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Antifungal compound process
BR112016021282A8 (pt) 2014-03-19 2021-07-20 The Us Secretary Department Of Health & Human Services processos para a preparação de compostos antifúngicos e os referidos compostos
EP3119745B1 (en) 2014-03-19 2020-08-05 Mycovia Pharmaceuticals, Inc. Antifungal compound process
JP6633539B2 (ja) * 2014-03-19 2020-01-22 ダウ アグロサイエンシィズ エルエルシー ２−（２，４−ジフルオロフェニル）−１，１−ジフルオロ−１−（５−置換−ピリジン−２−イル）−３−（１ｈ−テトラゾール−１−イル）プロパン−２−オールおよびその調製工程
AU2015231216B2 (en) 2014-03-19 2019-04-04 Mycovia Pharmaceuticals, Inc. Antifungal compound process
JP2017514790A (ja) 2014-03-19 2017-06-08 ヴィアメット ファーマスーティカルズ，インコーポレイテッド 抗真菌化合物の調製方法
JP6518683B2 (ja) 2014-03-19 2019-05-22 ヴィアメット ファーマスーティカルズ（エヌシー），インコーポレイテッド 抗真菌化合物の調製方法
AU2015231234B2 (en) 2014-03-19 2019-04-04 Mycovia Pharmaceuticals, Inc. Antifungal compound process
US9914726B2 (en) 2014-03-19 2018-03-13 Vps-3, Inc. 2-(2,4-difluorophenyl)-1,1-difluoro-1-(5-substituted-pyridin-2-yl)-3-(1H-tetrazol-1-yl)propan-2-ols and processes for their preparation
SI3271347T1 (sl) * 2015-03-19 2022-11-30 Mycovia Pharmaceuticals, Inc. Protiglivične spojine in postopki za izdelavo
AU2016323782B2 (en) * 2015-09-18 2020-11-26 Nqp 1598, Ltd. Antifungal compound process
WO2021188404A1 (en) * 2020-03-19 2021-09-23 Assia Chemical Industries Ltd Solid state forms of oteseconazole and process for preparation thereof
WO2023003554A1 (en) * 2021-07-22 2023-01-26 Mycovia Pharmaceuticals, Inc. Compositions comprising oteseconazole
CN119855811A (zh) * 2022-09-30 2025-04-18 上海济煜医药科技有限公司 双环类化合物的无定形、结晶固体及其制备方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
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US4921475A (en) 1983-08-18 1990-05-01 Drug Delivery Systems Inc. Transdermal drug patch with microtubes
US5087240A (en) 1983-08-18 1992-02-11 Drug Delivery Systems Inc. Transdermal drug patch with conductive fibers
US5163899A (en) 1987-03-20 1992-11-17 Drug Delivery Systems Inc. Transdermal drug delivery system
US5312325A (en) 1987-05-28 1994-05-17 Drug Delivery Systems Inc Pulsating transdermal drug delivery system
GB8804164D0 (en) 1988-02-23 1988-03-23 Tucker J M Bandage for administering physiologically active compound
US5008110A (en) 1988-11-10 1991-04-16 The Procter & Gamble Company Storage-stable transdermal patch
US5088977A (en) 1988-12-21 1992-02-18 Drug Delivery Systems Inc. Electrical transdermal drug applicator with counteractor and method of drug delivery
EP0431519B1 (en) 1989-12-04 1994-06-15 G.D. Searle & Co. System for transdermal albuterol administration
US5352456A (en) 1991-10-10 1994-10-04 Cygnus Therapeutic Systems Device for administering drug transdermally which provides an initial pulse of drug
JPH07502219A (ja) 1991-12-18 1995-03-09 ミネソタ　マイニング　アンド　マニュファクチャリング　カンパニー 多重層型バリアー構造体
EP0553769B1 (de) 1992-01-29 1996-01-03 FRANZ VÖLKL GmbH & CO. SKI UND TENNIS SPORTARTIKELFABRIK KG Ballspielschläger, insbesondere Tennisschläger
CA2485834C (en) 2002-05-16 2007-07-17 Tibotec Pharmaceuticals Ltd. Pseudopolymorphic forms of a hiv protease inhibitor
JP2009513698A (ja) * 2005-10-31 2009-04-02 デウン ファーマシューティカル カンパニー リミテッド 新規な抗菌トリアゾール誘導体
DE102008043697A1 (de) 2008-01-25 2009-07-30 Robert Bosch Gmbh Verfahren und Vorrichtung zur Bestimmung der Zusammensetzung eines Kraftstoffgemischs
KR101379370B1 (ko) 2010-04-24 2014-03-28 비아멧 파마슈티컬즈, 인코포레이티드 금속효소 억제제 화합물
IN2014DN06792A (es) 2012-01-20 2015-05-22 Viamet Pharmaceuticals Inc
BR112014017799A8 (pt) * 2012-01-20 2017-07-11 Viamet Pharmaceuticals Inc Compostos inibidores de metaloenzima
ITFI20120143A1 (it) * 2012-07-12 2014-01-13 Inalco S A S Di Giovanni Cipollett I & C Polimorfi idrati e anidri del 2'-o-fucosillattosio e loro metodi di produzione.
EP3119745B1 (en) 2014-03-19 2020-08-05 Mycovia Pharmaceuticals, Inc. Antifungal compound process
SI3271347T1 (sl) * 2015-03-19 2022-11-30 Mycovia Pharmaceuticals, Inc. Protiglivične spojine in postopki za izdelavo

Also Published As

Publication number Publication date
PT3271347T (pt) 2022-07-14
CN107428724B (zh) 2021-07-02
HUE059771T2 (hu) 2022-12-28
RS63566B1 (sr) 2022-10-31
US10370353B2 (en) 2019-08-06
HRP20221113T1 (hr) 2022-11-25
US20170121307A1 (en) 2017-05-04
EP3271347B1 (en) 2022-06-22
EA037556B1 (ru) 2021-04-14
BR112017018823A2 (pt) 2018-04-24
PL3271347T3 (pl) 2022-11-21
SI3271347T1 (sl) 2022-11-30
WO2016149486A1 (en) 2016-09-22
DK3271347T3 (da) 2022-07-18
CN107428724A (zh) 2017-12-01
EP3271347A4 (en) 2018-10-17
US20190210994A1 (en) 2019-07-11
EP3271347A1 (en) 2018-01-24
US10676459B2 (en) 2020-06-09
AU2016233113B2 (en) 2020-05-07
KR102603277B1 (ko) 2023-11-17
CA2978339C (en) 2021-08-03
US20190367476A1 (en) 2019-12-05
ES2926063T3 (es) 2022-10-21
LT3271347T (lt) 2022-10-10
KR20170129895A (ko) 2017-11-27
EA201792067A1 (ru) 2018-01-31
AU2016233113A1 (en) 2017-09-21
MX381344B (es) 2025-03-12
CA2978339A1 (en) 2016-09-22
US9840492B2 (en) 2017-12-12
US10414751B2 (en) 2019-09-17
US20180319768A1 (en) 2018-11-08

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