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MX2017004630A - Metodos para llevar a cabo estudios de estimulo-respuesta con celulas madre pluripotentes inducidas derivadas de celulas perinatales o tejidos. - Google Patents

Metodos para llevar a cabo estudios de estimulo-respuesta con celulas madre pluripotentes inducidas derivadas de celulas perinatales o tejidos.

Info

Publication number
MX2017004630A
MX2017004630A MX2017004630A MX2017004630A MX2017004630A MX 2017004630 A MX2017004630 A MX 2017004630A MX 2017004630 A MX2017004630 A MX 2017004630A MX 2017004630 A MX2017004630 A MX 2017004630A MX 2017004630 A MX2017004630 A MX 2017004630A
Authority
MX
Mexico
Prior art keywords
cells
ipscs
derived
stimulus
methods
Prior art date
Application number
MX2017004630A
Other languages
English (en)
Inventor
P Coyne Kevin
T Coyne Shawn
Original Assignee
Coyne Ip Holdings Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coyne Ip Holdings Llc filed Critical Coyne Ip Holdings Llc
Publication of MX2017004630A publication Critical patent/MX2017004630A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5073—Stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • General Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Transplantation (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Se proporcionan métodos en la presente para llevar a cabo estudios de estímulo-respuesta sobre el iPSC, o células derivadas de iPSC, que se han derivado de células perinatales recolectadas de donadores bajo condiciones de exposoma nulo. En algunas modalidades, se implican varios donadores. En otras modalidades, se diferencian las iPSC. El uso de células madre pluripotentes inducidas (iPSC) derivadas de células que se origina de neonatos permite que un científico remueva en gran medida las influencias de edad y exposiciones ambientales, permitiendo un análisis más orientado de la interacción directa entre un estímulo y un sujeto de prueba. Adicionalmente, el uso de las iPSC derivadas de células que se originan de varios donadores permite que el científico obtenga mediciones más precisas de la función de las diferencias quirúrgicas en determinar respuestas a un estímulo dado que el uso de otros materiales de prueba, de eliminar la vasta mayoría de influencias diferenciales de edad y medio ambiente entre los sujetos de prueba.
MX2017004630A 2014-10-15 2015-10-15 Metodos para llevar a cabo estudios de estimulo-respuesta con celulas madre pluripotentes inducidas derivadas de celulas perinatales o tejidos. MX2017004630A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462064067P 2014-10-15 2014-10-15
PCT/US2015/055637 WO2016061298A1 (en) 2014-10-15 2015-10-15 Methods for conducting stimulus-response studies with induced pluripotent stem cells derived from perinatal cells or tissues

Publications (1)

Publication Number Publication Date
MX2017004630A true MX2017004630A (es) 2017-06-20

Family

ID=55747308

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017004630A MX2017004630A (es) 2014-10-15 2015-10-15 Metodos para llevar a cabo estudios de estimulo-respuesta con celulas madre pluripotentes inducidas derivadas de celulas perinatales o tejidos.

Country Status (6)

Country Link
US (1) US20170307596A1 (es)
EP (1) EP3206498A4 (es)
JP (1) JP2017530716A (es)
CA (1) CA2964359A1 (es)
MX (1) MX2017004630A (es)
WO (1) WO2016061298A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017139756A1 (en) * 2016-02-11 2017-08-17 Coyne Ip Holdings, Llc Methods of ascertaining cross-subject quantitative relationships between response indicators among multiple subjects in a population using multipotent or pluripotent stem cells
WO2019060654A2 (en) * 2017-09-21 2019-03-28 Coyne Scientific, Llc METHODS OF ANALYZING THE INTERACTIVE EFFECTS OF MULTIPLE CHEMICAL OR BIOLOGICAL AGENTS ON HUMAN SUBJECTS USING STEM CELLS
EP4150633A1 (en) * 2020-05-14 2023-03-22 Universität Heidelberg Single-cell morphology analysis for disease profiling and drug discovery

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008307007A (ja) * 2007-06-15 2008-12-25 Bayer Schering Pharma Ag 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞
CN102803476A (zh) * 2009-09-14 2012-11-28 程临钊 血细胞重编程产生多潜能干细胞和多功能干细胞
GB201119335D0 (en) * 2011-11-09 2011-12-21 Univ Leuven Kath Hepatitis virus infectable stem cells
US20130157365A1 (en) * 2011-12-20 2013-06-20 Advanced Technologies And Regenerative Medicine, Llc Induced pluripotent stem cells from human umbilical cord tissue-derived cells
WO2015003178A1 (en) * 2013-07-03 2015-01-08 Coyne Scientific, Llc Methods for predicting responses to chemical or biologic substances

Also Published As

Publication number Publication date
WO2016061298A1 (en) 2016-04-21
US20170307596A1 (en) 2017-10-26
JP2017530716A (ja) 2017-10-19
EP3206498A1 (en) 2017-08-23
EP3206498A4 (en) 2018-03-28
CA2964359A1 (en) 2016-04-21

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