[go: up one dir, main page]

MX2017000041A - Formulaciones de liberacion inmediata disuasivas de abuso que comprenden polisacaridos no celulosicos. - Google Patents

Formulaciones de liberacion inmediata disuasivas de abuso que comprenden polisacaridos no celulosicos.

Info

Publication number
MX2017000041A
MX2017000041A MX2017000041A MX2017000041A MX2017000041A MX 2017000041 A MX2017000041 A MX 2017000041A MX 2017000041 A MX2017000041 A MX 2017000041A MX 2017000041 A MX2017000041 A MX 2017000041A MX 2017000041 A MX2017000041 A MX 2017000041A
Authority
MX
Mexico
Prior art keywords
immediate release
abuse deterrent
release formulations
deterrent immediate
cellulose polysaccharides
Prior art date
Application number
MX2017000041A
Other languages
English (en)
Other versions
MX382580B (es
Inventor
Micka Alex
Feng Kai
Chung Lai Tsz
Gaik Jonathan
Original Assignee
Mallinckrodt Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Llc filed Critical Mallinckrodt Llc
Publication of MX2017000041A publication Critical patent/MX2017000041A/es
Publication of MX382580B publication Critical patent/MX382580B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007Effervescent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893Tablet coating processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)

Abstract

La presente descripción proporciona composiciones farmacéuticas que proporcionan una liberación inmediata de ingredientes activos y tienen propiedades disuasivas de abuso. En particular, las composiciones farmacéuticas comprenden al menos un ingrediente farmacéuticamente activo, al menos un polisacárido no celulósico, al menos un polímero gelificante hidrofílico y un sistema efervescente.
MX2017000041A 2014-07-03 2015-07-01 Formulaciones de liberación inmediata disuasivas de abuso que comprenden polisacáridos no celulósicos. MX382580B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462020726P 2014-07-03 2014-07-03
PCT/US2015/038774 WO2016004170A1 (en) 2014-07-03 2015-07-01 Abuse deterrent immediate release formulations comprising non-cellulose polysaccharides

Publications (2)

Publication Number Publication Date
MX2017000041A true MX2017000041A (es) 2017-05-01
MX382580B MX382580B (es) 2025-03-13

Family

ID=55016221

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017000041A MX382580B (es) 2014-07-03 2015-07-01 Formulaciones de liberación inmediata disuasivas de abuso que comprenden polisacáridos no celulósicos.

Country Status (13)

Country Link
US (3) US11617712B2 (es)
EP (1) EP3164117B1 (es)
JP (1) JP6850131B2 (es)
AU (1) AU2015284078B2 (es)
BR (1) BR112016030648B1 (es)
CA (1) CA2953396C (es)
DK (1) DK3164117T3 (es)
ES (1) ES2963078T3 (es)
HU (1) HUE065006T2 (es)
MX (1) MX382580B (es)
PL (1) PL3164117T3 (es)
PT (1) PT3164117T (es)
WO (1) WO2016004170A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9993422B2 (en) 2012-04-18 2018-06-12 SpecGx LLC Immediate release, abuse deterrent pharmaceutical compositions
CA2953396C (en) 2014-07-03 2022-11-08 Mallinckrodt Llc Abuse deterrent immediate release formulations comprising non-cellulose polysaccharides
US9861629B1 (en) 2015-10-07 2018-01-09 Banner Life Sciences Llc Opioid abuse deterrent dosage forms
JP2019504072A (ja) * 2016-02-08 2019-02-14 スペックジーエックス エルエルシー 徐放性及び濫用抑止特性を有するグルコマンナン含有医薬組成物
US10335405B1 (en) 2016-05-04 2019-07-02 Patheon Softgels, Inc. Non-burst releasing pharmaceutical composition
US10335375B2 (en) 2017-05-30 2019-07-02 Patheon Softgels, Inc. Anti-overingestion abuse deterrent compositions
EP3473246A1 (en) 2017-10-19 2019-04-24 Capsugel Belgium NV Immediate release abuse deterrent formulations
KR102810926B1 (ko) 2017-12-20 2025-05-22 퍼듀 퍼머 엘피 남용 억제 황산모르핀 제형
WO2020068510A1 (en) 2018-09-25 2020-04-02 SpecGx LLC Abuse deterrent immediate release capsule dosage forms
CN110101679A (zh) * 2019-05-15 2019-08-09 上海宣泰生物科技有限公司 海藻小苏打微泡腾片及其制备方法和应用

Family Cites Families (89)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2211485A (en) 1940-08-13 Effervescent acetyl salicylic acid
JPS537495B2 (es) 1973-05-21 1978-03-18
US3980766A (en) 1973-08-13 1976-09-14 West Laboratories, Inc. Orally administered drug composition for therapy in the treatment of narcotic drug addiction
DE2530563C2 (de) 1975-07-09 1986-07-24 Bayer Ag, 5090 Leverkusen Analgetische Arzneimittel mit vermindertem Mißbrauchspotential
US4678661A (en) 1983-09-28 1987-07-07 Gerhard Gergely Effervescent composition and method of making same
JPH0747532B2 (ja) 1985-10-16 1995-05-24 花王株式会社 錠剤の製造方法
US5096714A (en) 1988-06-28 1992-03-17 Hauser-Kuhrts, Inc. Prolonged release drug tablet formulations
US4956182A (en) * 1989-03-16 1990-09-11 Bristol-Myers Company Direct compression cholestyramine tablet and solvent-free coating therefor
EP0676967A4 (en) 1992-12-30 1996-10-02 Fmc Corp RELEASED, EXTENDED, EASY TO PRODUCE EXCIPIENT, BASED ON KONJAC GLUCOMANNANE.
GB9401894D0 (en) 1994-02-01 1994-03-30 Rhone Poulenc Rorer Ltd New compositions of matter
US6071539A (en) 1996-09-20 2000-06-06 Ethypharm, Sa Effervescent granules and methods for their preparation
US6200604B1 (en) 1998-03-27 2001-03-13 Cima Labs Inc. Sublingual buccal effervescent
ES2190241T3 (es) 1998-09-10 2003-07-16 Nycomed Danmark As Compuestos farmaceuticos de liberacion rapida de substancias medicamentosas.
US20080102121A1 (en) 1998-11-02 2008-05-01 Elan Pharma International Limited Compositions comprising nanoparticulate meloxicam and controlled release hydrocodone
FR2785191B1 (fr) 1998-11-02 2002-05-31 Rhodia Chimie Sa Utilisation de gommes xanthanes pour la preparation de compositions pharmaceutiques
US6264981B1 (en) 1999-10-27 2001-07-24 Anesta Corporation Oral transmucosal drug dosage using solid solution
US6340471B1 (en) 1999-12-30 2002-01-22 Alvin Kershman Method for preparing solid delivery system for encapsulated and non-encapsulated pharmaceuticals
US6541025B1 (en) 1999-12-30 2003-04-01 Shear/Kershman Laboratories, Inc. Method for preparing solid delivery system for encapsulated and non-encapsulated pharmaceuticals
US6660302B1 (en) 2000-09-06 2003-12-09 Chr. Hansen, Inc. Dry-powder film coating composition and method of preparation
GB0102342D0 (en) 2001-01-30 2001-03-14 Smithkline Beecham Plc Pharmaceutical formulation
US20030068375A1 (en) 2001-08-06 2003-04-10 Curtis Wright Pharmaceutical formulation containing gelling agent
US20080050422A1 (en) 2001-10-12 2008-02-28 Monosolrx, Llc. Method of administering a film product containing a drug
WO2003032954A1 (en) 2001-10-17 2003-04-24 Dr. Reddy's Laboratories Ltd. Stabilized pharmaceutical formulations containing amlodipine maleate
AUPR839001A0 (en) 2001-10-19 2001-11-15 Eli Lilly And Company Dosage form, device and methods of treatment
US7776314B2 (en) 2002-06-17 2010-08-17 Grunenthal Gmbh Abuse-proofed dosage system
US20040005359A1 (en) 2002-06-27 2004-01-08 Cheng Xiu Xiu Controlled release oral dosage form
DE102004020220A1 (de) 2004-04-22 2005-11-10 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform
DE102005005446A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Bruchfeste Darreichungsformen mit retardierter Freisetzung
DE102004032051A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform
JP4939217B2 (ja) 2003-08-06 2012-05-23 グリューネンタ−ル・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 乱用防止剤形
US8075872B2 (en) 2003-08-06 2011-12-13 Gruenenthal Gmbh Abuse-proofed dosage form
DE10336400A1 (de) 2003-08-06 2005-03-24 Grünenthal GmbH Gegen Missbrauch gesicherte Darreichungsform
US20070048228A1 (en) 2003-08-06 2007-03-01 Elisabeth Arkenau-Maric Abuse-proofed dosage form
KR20130103818A (ko) 2003-10-10 2013-09-24 벨로시스 파마슈티컬스 에이/에스 피브레이트를 포함하는 고형 제제
US7201920B2 (en) 2003-11-26 2007-04-10 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse of opioid containing dosage forms
AU2013206525B2 (en) 2003-11-26 2015-09-10 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse of opioid containing dosage forms
US20050165038A1 (en) 2004-01-22 2005-07-28 Maxwell Gordon Analgetic dosage forms that are resistant to parenteral and inhalation dosing and have reduced side effects
WO2006002836A1 (de) 2004-07-01 2006-01-12 Losan Pharma Gmbh Brausezusammensetzungen von einschlafmitteln
DE102004032049A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Gegen Missbrauch gesicherte, orale Darreichungsform
US8093408B2 (en) 2005-06-21 2012-01-10 The Company Wockhardt Antidepressant oral pharmaceutical compositions
PL116330U1 (en) 2005-10-31 2007-04-02 Alza Corp Method for the reduction of alcohol provoked rapid increase in the released dose of the orally administered opioide with prolonged liberation
US8329744B2 (en) * 2005-11-02 2012-12-11 Relmada Therapeutics, Inc. Methods of preventing the serotonin syndrome and compositions for use thereof
US8652529B2 (en) 2005-11-10 2014-02-18 Flamel Technologies Anti-misuse microparticulate oral pharmaceutical form
US20090317355A1 (en) 2006-01-21 2009-12-24 Abbott Gmbh & Co. Kg, Abuse resistant melt extruded formulation having reduced alcohol interaction
DK2428205T3 (da) 2006-03-16 2012-10-22 Tris Pharma Inc Modificerede formuleringer indeholdende lægemiddel-ionbytterharpikskomplekser
CA2647809C (en) 2006-03-24 2016-08-16 Auxilium Pharmaceuticals, Inc. Stabilized compositions containing alkaline labile drugs
WO2007117605A2 (en) 2006-04-06 2007-10-18 Taro Pharmaceuticals North America, Inc. Novel spill-resistant formulations comprising hydrocolloidal polymers
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
ES2300188B1 (es) 2006-05-24 2009-05-01 Ferrer Internacional, S.A. Comprimido bicapa para la prevencion de los accidentes cardiovasculares.
US20080069891A1 (en) 2006-09-15 2008-03-20 Cima Labs, Inc. Abuse resistant drug formulation
SA07280459B1 (ar) 2006-08-25 2011-07-20 بيورديو فارما إل. بي. أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني
US8445018B2 (en) 2006-09-15 2013-05-21 Cima Labs Inc. Abuse resistant drug formulation
CA2679316C (en) 2007-03-02 2016-11-29 Teika Pharmaceutical Co., Ltd. Morphine composition for transdermal absorption, morphine composition storing unit and transdermal absorption preparation using the same
WO2008128191A2 (en) 2007-04-13 2008-10-23 Chemgenex Pharmaceuticals, Inc. Oral cephalotaxine dosage forms
WO2008149440A1 (ja) 2007-06-07 2008-12-11 Sato Pharmaceutical Co., Ltd. 速溶性及び可撓性を有するフィルム製剤
US20090124650A1 (en) 2007-06-21 2009-05-14 Endo Pharmaceuticals, Inc. Method of Treating Pain Utilizing Controlled Release Oxymorphone Pharmaceutical Compositions and Instructions on Effects of Alcohol
US10736850B2 (en) 2007-08-13 2020-08-11 Ohemo Life Sciences Inc. Abuse resistant oral opioid formulations
CA2700426C (en) 2007-09-25 2017-10-31 Galia Temtsin Krayz Compositions comprising lipophilic active compounds and method for their preparation
BRPI0821732A2 (pt) 2007-12-17 2015-06-16 Labopharm Inc Formulações de liberação controlada , forma de dosagem sólida, e, uso da formulação de liberação controlada
AU2009207796B2 (en) 2008-01-25 2014-03-27 Grunenthal Gmbh Pharmaceutical dosage form
US7918929B2 (en) 2008-02-19 2011-04-05 John Christopher Sunnucks Water erodible denture adhesive
US8729070B2 (en) 2008-02-20 2014-05-20 Targia Pharmaceuticals CNS pharmaceutical compositions and methods of use
CA2721815C (en) 2008-05-07 2014-06-10 Yasunori Tsuzuki Cyclic amine-1-carboxylic acid ester derivative and pharmaceutical composition containing the same
MX2011001288A (es) 2008-08-07 2011-03-21 Avantor Performance Mat Inc Composiciones de liberacion sostenida que comprenden gomas y alcoholes de azucar.
AU2009294308B2 (en) 2008-09-18 2013-05-30 Purdue Pharma L.P. Pharmaceutical dosage forms comprising poly(e-caprolactone)
WO2010035273A2 (en) 2008-09-29 2010-04-01 Intec Pharma Ltd. Novel gastroretentive delivery system
WO2010089132A1 (en) * 2009-02-06 2010-08-12 Egalet A/S Immediate release composition resistant to abuse by intake of alcohol
ES2607209T3 (es) * 2009-02-06 2017-03-29 Egalet Ltd. Composiciones farmacéuticas resistentes al abuso
GB0909680D0 (en) 2009-06-05 2009-07-22 Euro Celtique Sa Dosage form
AR077420A1 (es) 2009-07-22 2011-08-24 Gruenenthal Gmbh Forma de dosificacion resistente a la manipulacion para opiaceos sensibles a la oxidacion
MX2012000317A (es) 2009-07-22 2012-02-08 Gruenenthal Gmbh Forma de dosificacion de liberacion controlada extruida por fusion en caliente.
WO2011041414A1 (en) 2009-09-30 2011-04-07 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse
JP5017516B2 (ja) 2009-11-13 2012-09-05 株式会社ホットアルバム炭酸泉タブレット 錠剤の製造方法
WO2011066980A2 (en) 2009-12-04 2011-06-09 Lars Holger Hermann Oral dosage forms with reduced potential for drug abuse
WO2011079074A1 (en) 2009-12-24 2011-06-30 Acura Phamaceuticals, Inc. Pharmaceutical compositions for deterring misuse, abuse, and diversion
US20120321674A1 (en) 2011-02-17 2012-12-20 Michael Vachon Technology for Preventing Abuse of Solid Dosage Forms
NZ602075A (en) 2010-02-24 2014-01-31 Cima Labs Inc Abuse-resistant formulations
US20130202705A1 (en) 2010-05-11 2013-08-08 Cima Labs Inc. Alcohol-resistant formulations
MX2012012991A (es) 2010-05-11 2012-11-30 Cima Labs Inc Formas de dosificacion oral de liberacion prolongada resistentes al alcohol y que contienen metoprolol.
US20130171256A1 (en) 2010-05-11 2013-07-04 Cima Labs Inc. Alcohol-resistant extended release dosage forms comprising venlafaxine
EP2409683A1 (en) 2010-07-06 2012-01-25 KRKA, D.D., Novo Mesto Stable aqueous formulations comprising poorly water soluble active ingredients
JP2014505736A (ja) 2011-02-17 2014-03-06 キューアールエックスファーマ リミテッド 固体投薬形態の乱用を防止するための技術
EP2782558A4 (en) 2011-11-22 2015-03-18 Watson Pharmaceuticals Inc MISSABLE TABLET WITH IMMEDIATE RELEASE
US9993422B2 (en) * 2012-04-18 2018-06-12 SpecGx LLC Immediate release, abuse deterrent pharmaceutical compositions
CA2868416A1 (en) 2012-04-18 2013-10-24 Mallinckrodt Llc Immediate release pharmaceutical compositions with abuse deterrent properties
EA201590165A1 (ru) 2012-07-06 2015-08-31 Эгалет Лтд. Сдерживающие злоупотребление фармацевтические композиции для контролируемого высвобождения
CA2791206A1 (en) 2012-09-28 2014-03-28 Pharmascience Inc. Abuse deterrent pharmaceutical formulation
WO2014152296A1 (en) * 2013-03-15 2014-09-25 Mallinckrodt Llc Abuse deterrent solid dosage form for immediate release with functional score
CA2953396C (en) 2014-07-03 2022-11-08 Mallinckrodt Llc Abuse deterrent immediate release formulations comprising non-cellulose polysaccharides

Also Published As

Publication number Publication date
JP6850131B2 (ja) 2021-03-31
JP2017519783A (ja) 2017-07-20
MX382580B (es) 2025-03-13
PL3164117T3 (pl) 2024-03-11
US11517521B2 (en) 2022-12-06
EP3164117B1 (en) 2023-09-06
BR112016030648B1 (pt) 2023-10-03
AU2015284078A1 (en) 2017-01-05
CA2953396A1 (en) 2016-01-07
HUE065006T2 (hu) 2024-04-28
US20200368148A1 (en) 2020-11-26
US20180296467A1 (en) 2018-10-18
BR112016030648A2 (pt) 2021-09-08
ES2963078T3 (es) 2024-03-25
EP3164117A4 (en) 2017-12-06
US11583493B2 (en) 2023-02-21
US20160000703A1 (en) 2016-01-07
PT3164117T (pt) 2023-12-12
CA2953396C (en) 2022-11-08
AU2015284078B2 (en) 2020-01-30
WO2016004170A1 (en) 2016-01-07
US11617712B2 (en) 2023-04-04
DK3164117T3 (da) 2023-12-04
EP3164117A1 (en) 2017-05-10

Similar Documents

Publication Publication Date Title
MX2017000041A (es) Formulaciones de liberacion inmediata disuasivas de abuso que comprenden polisacaridos no celulosicos.
MX2014011815A (es) Composiciones farmaceuticas de liberacion inmediata con propiedades disuasivas de abuso.
MX356111B (es) Composiciones farmaceuticas disuasorias de abuso, de liberacion inmediata.
PH12019502058A1 (en) Farnesoid x receptor agonists and uses thereof
PH12018500586B1 (en) Farnesoid x receptor agonists and uses thereof
CA2956871C (en) Compounds active towards bromodomains
WO2015160975A3 (en) Combination of a pi3k inhibitor with a bcl-2 inhibitor for use in the treatment of cancer
WO2015165413A8 (zh) 一种新型的稳定型抗体药物耦联物及其制备方法和用途
PH12019501199A1 (en) Calcium lactate compositions and methods of use
MX2015000114A (es) Composiciones farmaceuticas disuasivas de abuso de liberacion prolongada.
MX2016012574A (es) Compuestos heteroarilo sustituidos y metodos de uso.
MX2011007817A (es) Formulacion farmaceutica o alimenticia de liberacion controlada y proceso para su preparacion.
IN2013MU03583A (es)
PH12017502376B1 (en) Oral solid formulation containing irinotecan and method of preparing the same
WO2015066302A3 (en) Compositions, methods of use, and methods of treatment
TR201713929A2 (tr) Ki̇tosan ve alji̇natin hemostati̇k kompozi̇syonlari
ZA201807446B (en) Improved drug formulations
BR112017009510A2 (pt) composições compreendendo ciclosporina
EP4342461A3 (en) Pharmaceutical compositions and uses directed to lysosomal storage disorders
WO2017079403A3 (en) Polymeric nanoparticles
WO2013170086A3 (en) Formulations for the delivery of active ingredients
WO2019043176A3 (en) HISTONE-DEACETYLASE INHIBITOR IN COMBINATION WITH ANTIMETABOLITE AGENT FOR CANCER THERAPY
MX2018009948A (es) Formulaciones de oritavancina.
MX2021002459A (es) Formas de dosificacion en capsula disuasorias del abuso de liberacion inmediata.
WO2014153643A8 (en) Compositions and methods for use thereof in the treatment of aniridia