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MX2016016380A - Composicion farmaceutica para usarse en la prevencion y/o tratamiento de enfermedades que se desarrollan o progresan como resultado de una disminucion o perdida de actividad del factor viii de coagulacion sanguinea activado. - Google Patents

Composicion farmaceutica para usarse en la prevencion y/o tratamiento de enfermedades que se desarrollan o progresan como resultado de una disminucion o perdida de actividad del factor viii de coagulacion sanguinea activado.

Info

Publication number
MX2016016380A
MX2016016380A MX2016016380A MX2016016380A MX2016016380A MX 2016016380 A MX2016016380 A MX 2016016380A MX 2016016380 A MX2016016380 A MX 2016016380A MX 2016016380 A MX2016016380 A MX 2016016380A MX 2016016380 A MX2016016380 A MX 2016016380A
Authority
MX
Mexico
Prior art keywords
coagulation factor
blood coagulation
factor viii
decrease
activity
Prior art date
Application number
MX2016016380A
Other languages
English (en)
Other versions
MX390728B (es
Inventor
Yoneyama Koichiro
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of MX2016016380A publication Critical patent/MX2016016380A/es
Publication of MX390728B publication Critical patent/MX390728B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/515—Complete light chain, i.e. VL + CL

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Se descubrió que la administración de una composición farmacéutica que comprende una molécula de unión al antígeno biespecífica que reconoce al factor de coagulación sanguínea IX y/o al factor de coagulación sanguínea IX activado y al factor de coagulación sanguínea X y/o al factor de coagulación sanguínea X activado de acuerdo con un régimen de dosificación dado, permite prevenir y/o tratar más eficazmente las enfermedades causadas y/o agravadas debido a una disminución o deficiencia de la actividad del factor de coagulación sanguínea VIII y/o del factor de coagulación sanguínea VIII activado.
MX2016016380A 2014-06-20 2015-03-31 Composicion farmaceutica para usarse en la prevencion y/o tratamiento de enfermedades que se desarrollan o progresan como resultado de una disminucion o perdida de actividad del factor viii de coagulacion sanguinea activado. MX390728B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2014127240 2014-06-20
JP2014226988 2014-11-07
PCT/JP2015/060171 WO2015194233A1 (ja) 2014-06-20 2015-03-31 血液凝固第ｖｉｉｉ因子および／または活性化血液凝固第ｖｉｉｉの活性の低下ないし欠損によって発症および／または進展する疾患の予防および／または治療に用いられる医薬組成物

Publications (2)

Publication Number Publication Date
MX2016016380A true MX2016016380A (es) 2017-04-06
MX390728B MX390728B (es) 2025-03-21

Family

ID=54935230

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016016380A MX390728B (es) 2014-06-20 2015-03-31 Composicion farmaceutica para usarse en la prevencion y/o tratamiento de enfermedades que se desarrollan o progresan como resultado de una disminucion o perdida de actividad del factor viii de coagulacion sanguinea activado.

Country Status (16)

Country Link
US (11) US20170253663A1 (es)
EP (2) EP4218816A3 (es)
JP (2) JP6663846B2 (es)
KR (2) KR20240063162A (es)
CN (1) CN106559987A (es)
AU (1) AU2015275440B2 (es)
BR (1) BR112016029316A2 (es)
CA (1) CA2951622C (es)
IL (1) IL249330B (es)
MX (1) MX390728B (es)
MY (1) MY189333A (es)
RU (1) RU2721910C2 (es)
SG (2) SG10201811185YA (es)
TW (2) TWI831106B (es)
WO (1) WO2015194233A1 (es)
ZA (1) ZA201700459B (es)

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CN119161488A (zh) 2017-11-01 2024-12-20 中外制药株式会社 具有降低的生物活性的抗体变体和同种型
CN118745229A (zh) * 2017-11-15 2024-10-08 诺和诺德股份有限公司 增强fx活化的因子x结合物
JP7530362B2 (ja) 2018-12-21 2024-08-07 カイマブ・リミテッド 共通の軽鎖を有するＦＩＸａ×ＦＸ二重特異性抗体
JP6836696B1 (ja) * 2019-10-11 2021-03-03 中外製薬株式会社 後天性血友病ａの予防および／または治療に用いられる医薬組成物、および当該医薬組成物を含む製品
TW202207984A (zh) * 2019-10-11 2022-03-01 日商中外製藥股份有限公司 用於後天性血友病a之預防及/或治療之醫藥組成物、及包含該醫藥組成物之製品
KR102839225B1 (ko) 2022-03-02 2025-07-29 노보 노르디스크 헬스 케어 악티엔게젤샤프트 Fviii 모방 이중특이적 항체의 주 1회 투여 방법
KR102868672B1 (ko) 2022-03-02 2025-10-14 노보 노르디스크 헬스 케어 악티엔게젤샤프트 Fviii 모방 이중특이적 항체를 2주마다 1회 투여하는 방법
KR102839278B1 (ko) 2022-03-02 2025-07-30 노보 노르디스크 헬스 케어 악티엔게젤샤프트 Fviii 모방 이중특이적 항체의 월 1회 투여 방법
CN121038814A (zh) * 2023-04-14 2025-11-28 中外制药株式会社 用于稳定含蛋白质药物制剂的方法
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WO2025134341A1 (ja) * 2023-12-22 2025-06-26 中外製薬株式会社 抗体の製造方法
WO2026011751A1 (zh) * 2024-07-08 2026-01-15 武汉友芝友生物制药股份有限公司 抗体制剂

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Also Published As

Publication number Publication date
BR112016029316A2 (pt) 2018-02-20
TWI831106B (zh) 2024-02-01
RU2017101705A (ru) 2018-07-27
US20170253663A1 (en) 2017-09-07
US20220073645A1 (en) 2022-03-10
EP4218816A3 (en) 2023-09-13
US20200157243A1 (en) 2020-05-21
US20220324999A1 (en) 2022-10-13
US20240317891A1 (en) 2024-09-26
JP2020055864A (ja) 2020-04-09
MY189333A (en) 2022-02-04
SG10201811185YA (en) 2019-01-30
JP6663846B2 (ja) 2020-03-13
KR20170015517A (ko) 2017-02-08
JPWO2015194233A1 (ja) 2017-04-20
KR20240063162A (ko) 2024-05-09
US20210238307A1 (en) 2021-08-05
EP4218816A2 (en) 2023-08-02
US20230174673A1 (en) 2023-06-08
MX390728B (es) 2025-03-21
IL249330A0 (en) 2017-02-28
CA2951622C (en) 2023-01-03
RU2721910C2 (ru) 2020-05-25
NZ727218A (en) 2023-08-25
CN106559987A (zh) 2017-04-05
TW201625299A (zh) 2016-07-16
EP3159006A1 (en) 2017-04-26
EP3159006A4 (en) 2018-01-03
TW202241504A (zh) 2022-11-01
US20190309090A1 (en) 2019-10-10
ZA201700459B (en) 2021-07-28
US20200407463A1 (en) 2020-12-31
US20260001965A1 (en) 2026-01-01
WO2015194233A1 (ja) 2015-12-23
SG11201610581RA (en) 2017-01-27
RU2017101705A3 (es) 2018-11-01
AU2015275440A1 (en) 2017-01-12
IL249330B (en) 2021-07-29
AU2015275440B2 (en) 2020-07-16
US20240052060A1 (en) 2024-02-15
CA2951622A1 (en) 2015-12-23

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