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MX2016015287A - Copolimeros de quitosan y polietilenglicol y metodos y dispositivos para usar los mismos para sellar una puncion vascular. - Google Patents

Copolimeros de quitosan y polietilenglicol y metodos y dispositivos para usar los mismos para sellar una puncion vascular.

Info

Publication number
MX2016015287A
MX2016015287A MX2016015287A MX2016015287A MX2016015287A MX 2016015287 A MX2016015287 A MX 2016015287A MX 2016015287 A MX2016015287 A MX 2016015287A MX 2016015287 A MX2016015287 A MX 2016015287A MX 2016015287 A MX2016015287 A MX 2016015287A
Authority
MX
Mexico
Prior art keywords
section
puncture
chitosan
sealing
methods
Prior art date
Application number
MX2016015287A
Other languages
English (en)
Inventor
MYLONAKIS Andreas
Lim Florencia
Original Assignee
Access Closure Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Access Closure Inc filed Critical Access Closure Inc
Publication of MX2016015287A publication Critical patent/MX2016015287A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0031—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/06—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/08—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/145—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148—Materials at least partially resorbable by the body
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
    • A61B2017/00623—Introducing or retrieving devices therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00646—Type of implements
    • A61B2017/0065—Type of implements the implement being an adhesive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

Landscapes

  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Materials Engineering (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Biomedical Technology (AREA)
  • Materials For Medical Uses (AREA)
  • Surgical Instruments (AREA)
  • Medicinal Preparation (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Sealing Material Composition (AREA)

Abstract

Se proporciona un sellador para sellar una punción a través del tejido que comprende una primera sección alargada que incluye un extremo próximo, un extremo distal, y una sección transversal dimensionada para el suministro en una punción a través de tejido, y una segunda sección que se extiende desde el extremo distal de la primera sección. La primera sección se puede formar de un hidrogel secado por congelación que se expande cuando se expone al fluido fisiológico dentro de una punción. La primera sección comprende quitosan y al menos un polímero adicional. La segunda sección se puede formar de una masa sólida de precursores de hidrogel no reticulados, no secados por congelación. Los precursores están en un estado no reactivo hasta que se exponen a un medio ambiente fisiológico acuoso, después de lo cual los precursores se someten a reticulación in situ entre sí para proporcionar una capa adhesiva unida a la primera sección. La segunda sección puede comprender además quitosan. También se proporcionan aparatos y métodos para suministrar el sellador en una punción a través del tejido.
MX2016015287A 2014-05-29 2015-05-28 Copolimeros de quitosan y polietilenglicol y metodos y dispositivos para usar los mismos para sellar una puncion vascular. MX2016015287A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462004806P 2014-05-29 2014-05-29
PCT/US2015/033020 WO2015184160A1 (en) 2014-05-29 2015-05-28 Chitosan and polyethylene glycol copolymers and methods and devices for using same for sealing a vascular puncture

Publications (1)

Publication Number Publication Date
MX2016015287A true MX2016015287A (es) 2017-05-09

Family

ID=53396584

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2016015287A MX2016015287A (es) 2014-05-29 2015-05-28 Copolimeros de quitosan y polietilenglicol y metodos y dispositivos para usar los mismos para sellar una puncion vascular.
MX2020002757A MX391114B (es) 2014-05-29 2015-05-28 Copolímeros de quitosan y polietilenglicol y métodos y dispositivos para usar los mismos para sellar una punción vascular.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2020002757A MX391114B (es) 2014-05-29 2015-05-28 Copolímeros de quitosan y polietilenglicol y métodos y dispositivos para usar los mismos para sellar una punción vascular.

Country Status (14)

Country Link
US (4) US9861348B2 (es)
EP (2) EP4032563B1 (es)
JP (4) JP6681343B2 (es)
KR (3) KR20240135881A (es)
CN (2) CN111643129B (es)
AU (4) AU2015266837B2 (es)
BR (2) BR112016027378B1 (es)
CA (1) CA2949842A1 (es)
CL (1) CL2016002946A1 (es)
IL (1) IL249096B2 (es)
MX (2) MX2016015287A (es)
NZ (1) NZ756435A (es)
RU (1) RU2696139C2 (es)
WO (1) WO2015184160A1 (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA40946A (fr) 2014-11-14 2017-09-19 Access Closure Inc Appareil et procédés permettant de rendre étanche une ponction vasculaire
USD865166S1 (en) 2015-11-13 2019-10-29 Access Closure, Inc. Sheath adapter
USD843573S1 (en) 2015-11-13 2019-03-19 Access Closure, Inc. Vascular closure apparatus
USD847988S1 (en) 2015-11-13 2019-05-07 Access Closure, Inc. Handle grip
KR101989054B1 (ko) * 2017-11-28 2019-06-13 (주)다림티센 지혈용 조성물 및 이를 포함하는 용기
WO2019147950A1 (en) * 2018-01-29 2019-08-01 Access Closure, Inc. Apparatus and method for sealing a vascular puncture
CN110193091A (zh) * 2018-02-27 2019-09-03 华东理工大学 可注射蛋白/聚乙二醇基水凝胶材料及其制备方法和应用
JP7248654B2 (ja) * 2018-03-29 2023-03-29 テルモ株式会社 塞栓材
US11241239B2 (en) * 2018-05-15 2022-02-08 Boston Scientific Scimed, Inc. Occlusive medical device with charged polymer coating
CN108784772B (zh) * 2018-07-30 2024-04-16 中国人民解放军总医院第四医学中心 一种伸缩式止血气囊
CN110478528B (zh) * 2019-08-14 2021-12-17 暨南大学 一种新型的促组织修复材料的制备方法及其应用
JP2023522317A (ja) * 2020-04-14 2023-05-30 デインデ・メディカル・コープ 生物組織膜を密封するための閉鎖デバイスおよび方法
CN111603604B (zh) * 2020-05-26 2021-11-30 山东朱氏药业集团有限公司 一种聚对二氧杂环己酮高强度高抗菌缝合线及制备方法
US12383246B2 (en) 2020-10-12 2025-08-12 Abbott Cardiovascular Systems, Inc. Vessel closure device with improved safety and tract hemostasis
CN116158798A (zh) * 2021-11-24 2023-05-26 杭州矩正医疗科技有限公司 血管封堵件及血管闭合装置
CN114481392A (zh) * 2022-01-06 2022-05-13 西安工程大学 一种纳米纤维包覆纱及其制备方法、纳米纤维包覆纱股线及其应用
PE20251096A1 (es) * 2022-02-10 2025-04-15 Avana Health Inc Dispositivo para tratar la hemorragia uterina y metodo de uso
CN114920962A (zh) * 2022-05-27 2022-08-19 上海益思妙医疗器械有限公司 一种止血材料的制备方法
WO2024054482A1 (en) * 2022-09-06 2024-03-14 University Of South Florida Composition for photochemical tissue bonding
CN118000809A (zh) * 2022-11-10 2024-05-10 深圳市先健纬康科技有限公司 一种穿刺孔闭合装置
CN118216969B (zh) * 2024-04-28 2026-01-02 通桥医疗科技有限公司 一种用于密封穿刺孔的设备
CN118986454B (zh) * 2024-10-25 2025-07-08 慧扬医疗科技(苏州)有限公司 一种血管闭合器
CN119548185B (zh) * 2025-01-23 2025-06-20 上海形状记忆合金材料有限公司 一种封堵止血装置

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4394373A (en) 1981-04-06 1983-07-19 Malette William Graham Method of achieving hemostasis
US4890612A (en) * 1987-02-17 1990-01-02 Kensey Nash Corporation Device for sealing percutaneous puncture in a vessel
US5264214A (en) * 1988-11-21 1993-11-23 Collagen Corporation Composition for bone repair
US5334216A (en) 1992-12-10 1994-08-02 Howmedica Inc. Hemostatic plug
US5814567A (en) 1996-06-14 1998-09-29 Kimberly-Clark Worldwide, Inc. Durable hydrophilic coating for a porous hydrophobic substrate
US7351421B2 (en) * 1996-11-05 2008-04-01 Hsing-Wen Sung Drug-eluting stent having collagen drug carrier chemically treated with genipin
US6703047B2 (en) 2001-02-02 2004-03-09 Incept Llc Dehydrated hydrogel precursor-based, tissue adherent compositions and methods of use
US6605294B2 (en) 1998-08-14 2003-08-12 Incept Llc Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels
US7335220B2 (en) 2004-11-05 2008-02-26 Access Closure, Inc. Apparatus and methods for sealing a vascular puncture
EP1223986A2 (en) * 1999-06-11 2002-07-24 Shearwater Corporation Hydrogels derived from chitosan and poly(ethylene glycol)
US6569185B2 (en) 2001-02-15 2003-05-27 Scimed Life Systems Inc Continuous infusion technique for arterial sealing
US7700819B2 (en) * 2001-02-16 2010-04-20 Kci Licensing, Inc. Biocompatible wound dressing
US8430934B2 (en) * 2002-03-01 2013-04-30 Regents Of The University Of Minnesota Vascular occlusion device
US7166133B2 (en) 2002-06-13 2007-01-23 Kensey Nash Corporation Devices and methods for treating defects in the tissue of a living being
US7998188B2 (en) * 2003-04-28 2011-08-16 Kips Bay Medical, Inc. Compliant blood vessel graft
US7331979B2 (en) 2003-06-04 2008-02-19 Access Closure, Inc. Apparatus and methods for sealing a vascular puncture
US20070219583A1 (en) 2003-06-12 2007-09-20 Sing Eduardo C System And Method For Facilitating Hemostatis With An Absorbable Sponge
US20050123588A1 (en) * 2003-06-16 2005-06-09 Zhu Yong H. Deployable multifunctional hemostatic agent
ATE502580T1 (de) * 2003-08-14 2011-04-15 Univ Loma Linda Med Vorrichtung zum verschluss von gefässwunden
US20050175659A1 (en) 2004-02-09 2005-08-11 Macomber Laurel R. Collagen device and method of preparing the same
US7806856B2 (en) 2005-04-22 2010-10-05 Accessclosure, Inc. Apparatus and method for temporary hemostasis
JP2007001963A (ja) * 2005-06-21 2007-01-11 Koji Kibune 吸水性の高いキトサンスポンジの製造方法
US8795709B2 (en) 2006-03-29 2014-08-05 Incept Llc Superabsorbent, freeze dried hydrogels for medical applications
TWI436793B (zh) 2006-08-02 2014-05-11 巴克斯特國際公司 快速作用之乾密封膠及其使用和製造方法
WO2008033964A2 (en) 2006-09-13 2008-03-20 Accessclosure, Inc. Apparatus for sealing a vascular puncture
US7993367B2 (en) 2007-09-28 2011-08-09 Accessclosure, Inc. Apparatus and methods for sealing a vascular puncture
AU2008317874B2 (en) 2007-10-30 2013-12-19 Baxter Healthcare S.A. Use of a regenerative biofunctional collagen biomatrix for treating visceral or parietal defects
WO2009059217A2 (en) 2007-11-02 2009-05-07 Incept, Llc Apparatus and methods for sealing a vascular puncture
US7868123B2 (en) 2007-11-19 2011-01-11 Ethicon, Inc. Derivatized tertiary amines and uses thereof
US8029533B2 (en) 2008-04-04 2011-10-04 Accessclosure, Inc. Apparatus and methods for sealing a vascular puncture
CA2721938C (en) * 2008-04-24 2016-08-09 Medtronic, Inc. Chitosan-containing protective composition
WO2010056915A1 (en) 2008-11-12 2010-05-20 Accessclosure, Inc. Apparatus and methods for sealing a vascular puncture
CA2750242C (en) 2009-02-12 2018-05-22 Incept, Llc Drug delivery through hydrogel plugs
US8529598B2 (en) * 2009-02-20 2013-09-10 Boston Scientific Scimed, Inc. Tissue puncture closure device
US8292918B2 (en) 2009-02-20 2012-10-23 Boston Scientific Scimed, Inc. Composite plug for arteriotomy closure and method of use
EP2427233B1 (en) 2009-05-04 2016-12-21 Incept Llc Biomaterials for track and puncture closure
NZ599524A (en) * 2009-11-09 2014-04-30 Spotlight Technology Partners Llc Polysaccharide based hydrogels
EP2498764B1 (en) * 2009-11-09 2017-09-06 Spotlight Technology Partners LLC Fragmented hydrogels
US10182800B2 (en) * 2011-01-19 2019-01-22 Access Closure, Inc. Apparatus and methods for sealing a vascular puncture
US10226417B2 (en) 2011-09-16 2019-03-12 Peter Jarrett Drug delivery systems and applications
US20150328062A9 (en) * 2011-11-10 2015-11-19 Covidien Lp Hydrophilic medical devices
EP3342448B1 (en) * 2012-03-23 2019-12-04 Access Closure, Inc. Apparatus for sealing a vascular puncture
BR112014030858A2 (pt) * 2012-06-11 2017-06-27 E Pacing Inc dispositivos e métodos de fechamento de vasculatura

Also Published As

Publication number Publication date
RU2016147920A3 (es) 2018-11-14
RU2019123291A (ru) 2020-04-28
CN111643129B (zh) 2024-06-11
AU2015266837B2 (en) 2019-04-04
AU2023237172A1 (en) 2023-10-19
CL2016002946A1 (es) 2017-04-17
MX391114B (es) 2025-03-21
IL249096B2 (en) 2023-08-01
MX2020002757A (es) 2022-03-30
CA2949842A1 (en) 2015-12-03
BR122019024398B1 (pt) 2021-08-17
JP2023134589A (ja) 2023-09-27
KR20170033812A (ko) 2017-03-27
NZ756435A (en) 2022-12-23
JP2017517316A (ja) 2017-06-29
NZ727124A (en) 2020-10-30
JP6681343B2 (ja) 2020-04-15
AU2019204615A1 (en) 2019-07-18
CN106456846A (zh) 2017-02-22
KR20220144883A (ko) 2022-10-27
RU2016147920A (ru) 2018-07-03
KR102454789B1 (ko) 2022-10-17
WO2015184160A1 (en) 2015-12-03
IL249096A0 (en) 2017-01-31
US9861348B2 (en) 2018-01-09
AU2015266837A1 (en) 2016-12-22
JP2021151492A (ja) 2021-09-30
AU2021204805A1 (en) 2021-08-05
BR112016027378A2 (pt) 2018-06-26
EP4032563B1 (en) 2026-01-07
CN106456846B (zh) 2020-05-15
CN111643129A (zh) 2020-09-11
US20210030405A1 (en) 2021-02-04
JP6890191B2 (ja) 2021-06-18
RU2696139C2 (ru) 2019-07-31
US11751857B2 (en) 2023-09-12
US20150342581A1 (en) 2015-12-03
AU2023237172B2 (en) 2026-02-05
US20180168562A1 (en) 2018-06-21
EP3148602A1 (en) 2017-04-05
AU2019204615B2 (en) 2021-04-08
EP3148602B1 (en) 2021-12-22
IL249096B1 (en) 2023-04-01
BR112016027378B1 (pt) 2021-03-23
JP2020089743A (ja) 2020-06-11
KR102703232B1 (ko) 2024-09-06
US20180168563A1 (en) 2018-06-21
KR20240135881A (ko) 2024-09-12
EP4032563A1 (en) 2022-07-27

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