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MX2018005542A - Composicion para administracion de farmacos que contiene polimeros de sililo. - Google Patents

Composicion para administracion de farmacos que contiene polimeros de sililo.

Info

Publication number
MX2018005542A
MX2018005542A MX2018005542A MX2018005542A MX2018005542A MX 2018005542 A MX2018005542 A MX 2018005542A MX 2018005542 A MX2018005542 A MX 2018005542A MX 2018005542 A MX2018005542 A MX 2018005542A MX 2018005542 A MX2018005542 A MX 2018005542A
Authority
MX
Mexico
Prior art keywords
composition containing
drug delivery
delivery composition
containing silyl
silyl polymers
Prior art date
Application number
MX2018005542A
Other languages
English (en)
Inventor
Goubard David
Haddleton David
O'driscoll Ciaran
Original Assignee
Medherant Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1519321.2A external-priority patent/GB201519321D0/en
Priority claimed from GBGB1602907.6A external-priority patent/GB201602907D0/en
Application filed by Medherant Ltd filed Critical Medherant Ltd
Publication of MX2018005542A publication Critical patent/MX2018005542A/es

Links

Classifications

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    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
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    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Virology (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)

Abstract

La invención se refiere a un polímero que contiene sililo, que se usa, junto con una resina adherente, para formar una composición adhesiva capaz de almacenar y administrar fármacos a la piel de un usuario. Típicamente, la composición se conforma en un parche que muestra una excelente adhesión a la piel incluso cuando los fármacos y otros aditivos se disuelven en la composición.
MX2018005542A 2015-11-02 2016-11-02 Composicion para administracion de farmacos que contiene polimeros de sililo. MX2018005542A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1519321.2A GB201519321D0 (en) 2015-11-02 2015-11-02 Drug delivery system
GBGB1602907.6A GB201602907D0 (en) 2016-02-19 2016-02-19 Drug delivery composition
PCT/GB2016/053388 WO2017077284A1 (en) 2015-11-02 2016-11-02 Drug delivery composition containing silyl polymers

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MX2018005542A true MX2018005542A (es) 2018-11-09

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EP (1) EP3370696A1 (es)
JP (1) JP6889172B2 (es)
KR (1) KR20180105637A (es)
CN (1) CN108289831B (es)
AU (1) AU2016348839A1 (es)
BR (1) BR112018008784A2 (es)
CA (1) CA3003957A1 (es)
IL (1) IL258994A (es)
MX (1) MX2018005542A (es)
PH (1) PH12018500930A1 (es)
RU (1) RU2737707C2 (es)
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ZA (1) ZA201802982B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201706969D0 (en) * 2017-05-02 2017-06-14 Medherant Ltd Formulation
GB2562070A (en) * 2017-05-03 2018-11-07 Medherant Ltd Drug delivery composition
FR3069551B1 (fr) * 2017-07-28 2020-08-07 Bostik Sa Composition adhesive reticulable par chauffage
GB201811833D0 (en) 2018-07-19 2018-09-05 Medherant Ltd Patch
GB201811834D0 (en) * 2018-07-19 2018-09-05 Medherant Ltd Patch
GB202112812D0 (en) 2021-09-08 2021-10-20 Medherant Ltd Patch

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0363061A (ja) * 1989-07-31 1991-03-19 Sanyo Chem Ind Ltd 医療用接着剤
JP2867442B2 (ja) * 1989-08-01 1999-03-08 東芝ホームテクノ株式会社 炊飯器
CA2053462A1 (en) * 1990-10-22 1992-04-23 Yoshiaki Yano Sticky composition for medical use
JPH05936A (ja) * 1990-10-25 1993-01-08 Kanegafuchi Chem Ind Co Ltd 経皮吸収製剤
JPH0753663A (ja) * 1993-07-30 1995-02-28 Takiron Co Ltd 経皮吸収製剤用基剤ポリマー
US6723077B2 (en) * 2001-09-28 2004-04-20 Hewlett-Packard Development Company, L.P. Cutaneous administration system
MY145980A (en) * 2003-03-26 2012-05-31 Sigmakalon Services B V Process for the preparation of poly(silyl esters)s, and their uses
US7332540B2 (en) 2004-02-18 2008-02-19 Eastman Chemical Company Aromatic-acrylate tackifier resins
US20050288415A1 (en) * 2004-06-23 2005-12-29 Beers Melvin D Highly elastomeric and paintable silicone compositions
WO2007145996A2 (en) * 2006-06-06 2007-12-21 Dow Corning Corporation A silicone acrylate hybrid composition
US7829116B2 (en) 2006-11-14 2010-11-09 Momentive Performance Materials Inc. Adhesive-forming composition and blend of adhesives obtained therefrom
FR2925517B1 (fr) 2007-12-21 2010-01-08 Bostik Sa Adhesifs sensibles a la pression a pouvoir adhesif stable en temperature.
DE102009046362A1 (de) * 2009-11-03 2011-05-05 Tesa Se Haftklebestoff aus einem vernetzbaren Polyolefin und einem Klebharz
FR2954341B1 (fr) * 2009-12-21 2014-07-11 Bostik Sa Composition adhesive reticulable par chauffage
FR2969621B1 (fr) 2010-12-22 2013-01-18 Bostik Sa Polyurethane a blocs polyether et polyester et groupe terminal alkoxysilane
US9440996B2 (en) * 2011-09-29 2016-09-13 Covestro Deutschland Ag Alpha-alkoxysilane-terminated prepolymer for fast-curing spray foams with improved propellant gas solubility
CN103827160A (zh) * 2011-09-29 2014-05-28 拜耳知识产权有限责任公司 快速固化的烷氧基硅烷喷涂泡沫
ES2728431T3 (es) * 2012-03-12 2019-10-24 Bostik Sa Artículos auto-adhesivos transpirables
EP2856937B1 (en) 2012-05-28 2021-08-18 Nipro Corporation Electrode pad for use on living organism
EP2682444A1 (en) * 2012-07-06 2014-01-08 Bostik SA Use of an adhesive composition to provide a bonding in a wet environment
EP2789636A1 (de) * 2013-04-10 2014-10-15 Sika Technology AG Primerlose Haftung von Kleb- und Dichtstoffen auf Basis von silanfunktionellen Polymeren
FR3012465B1 (fr) 2013-10-24 2015-11-13 Bostik Sa Autoadhesif d'origine renouvelable a pouvoir adhesif stable en temperature
FR3015983B1 (fr) 2013-12-30 2016-02-05 Bostik Sa Article auto-adhesif supporte sur mousse
FR3015984B1 (fr) * 2013-12-30 2016-02-05 Bostik Sa Article auto-adhesif supporte sur mousse

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US20180318233A1 (en) 2018-11-08
KR20180105637A (ko) 2018-09-28
RU2018118066A (ru) 2019-12-05
IL258994A (en) 2018-07-31
RU2737707C2 (ru) 2020-12-02
WO2017077284A1 (en) 2017-05-11
US11160764B2 (en) 2021-11-02
CA3003957A1 (en) 2017-05-11
JP6889172B2 (ja) 2021-06-18
ZA201802982B (en) 2019-07-31
PH12018500930A1 (en) 2019-01-28
JP2018532787A (ja) 2018-11-08
RU2018118066A3 (es) 2020-03-02
AU2016348839A1 (en) 2018-05-31
EP3370696A1 (en) 2018-09-12
BR112018008784A2 (pt) 2018-10-30
CN108289831A (zh) 2018-07-17
CN108289831B (zh) 2021-11-19

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