MX2016012319A - Formulaciones antihelminticas veterinarias estables. - Google Patents
Formulaciones antihelminticas veterinarias estables.Info
- Publication number
- MX2016012319A MX2016012319A MX2016012319A MX2016012319A MX2016012319A MX 2016012319 A MX2016012319 A MX 2016012319A MX 2016012319 A MX2016012319 A MX 2016012319A MX 2016012319 A MX2016012319 A MX 2016012319A MX 2016012319 A MX2016012319 A MX 2016012319A
- Authority
- MX
- Mexico
- Prior art keywords
- anthelmintic
- methods
- stable veterinary
- veterinary formulations
- stable
- Prior art date
Links
- 230000000507 anthelmentic effect Effects 0.000 title abstract 4
- 238000009472 formulation Methods 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 4
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 abstract 4
- 229940124339 anthelmintic agent Drugs 0.000 abstract 2
- 239000000921 anthelmintic agent Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- HLFSDGLLUJUHTE-SNVBAGLBSA-N Levamisole Chemical compound C1([C@H]2CN3CCSC3=N2)=CC=CC=C1 HLFSDGLLUJUHTE-SNVBAGLBSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000003785 benzimidazolyl group Chemical class N1=C(NC2=C1C=CC=C2)* 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 150000002596 lactones Chemical class 0.000 abstract 1
- 229960001614 levamisole Drugs 0.000 abstract 1
- 244000045947 parasite Species 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A61K9/0017—Non-human animal skin, e.g. pour-on, spot-on
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Organic Chemistry (AREA)
- Plant Pathology (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Toxicology (AREA)
Abstract
Se describen en la presente formulaciones veterinarias estables y los métodos de tratamiento y uso, que comprenden al menos una lactona macrocíclica y levamisol como agentes antihelmínticos activos, opcionalmente también con al menos un antihelmíntico de la clase bencimidazol, en donde los ingredientes activos se disuelven juntos en un sistema de solventes que comprende dimetilsulfóxido (DMSO). Las formulaciones veterinarias, métodos y uso de las mismas incluyen la capacidad de suministrar dos o más activos antihelmínticos en la única solución (o suspensión) mientras que también mantengan la estabilidad de la formulación cuando se almacenan durante un período de tiempo. El suministro de diferentes antihelmínticos con diferentes actividades permite que se dirijan a diversas clases de parásitos en una sola dosis.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NZ622869A NZ622869A (en) | 2014-03-24 | 2014-03-24 | Stable veterinary anthelmintic formulations |
| PCT/NZ2015/000018 WO2015147655A1 (en) | 2014-03-24 | 2015-03-24 | Stable veterinary anthelmintic formulations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2016012319A true MX2016012319A (es) | 2017-01-06 |
| MX389554B MX389554B (es) | 2025-03-20 |
Family
ID=52464905
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016012319A MX389554B (es) | 2014-03-24 | 2015-03-24 | Formulaciones antihelminticas veterinarias estables. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10449179B2 (es) |
| EP (1) | EP3122352A4 (es) |
| CN (1) | CN106132409B (es) |
| AR (1) | AR099829A1 (es) |
| AU (3) | AU2015237371A1 (es) |
| CA (1) | CA2942008C (es) |
| MX (1) | MX389554B (es) |
| NZ (2) | NZ622869A (es) |
| RU (1) | RU2711200C2 (es) |
| UY (1) | UY36045A (es) |
| WO (1) | WO2015147655A1 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018038623A1 (en) * | 2016-08-23 | 2018-03-01 | Donaghys Limited | Improvements in parasite treatments |
| EA201992125A1 (ru) | 2017-03-17 | 2020-03-16 | КРКА, д.д., НОВО МЕСТО | Стабильная ветеринарная композиция для местного применения |
| EP3829664A4 (en) | 2018-08-03 | 2022-05-04 | Nectero Medical, Inc. | PURIFIED PENTAGALLOYGLUCOSE AND DELIVERY DEVICES |
| JP7199653B2 (ja) * | 2018-08-17 | 2023-01-06 | 住化エンバイロメンタルサイエンス株式会社 | 樹脂製容器入り外部寄生虫駆除剤 |
| WO2020198371A1 (en) * | 2019-03-26 | 2020-10-01 | Nectero Medical, Inc. | Methods and devices for treatment of post-surgery laxity of tendons and tendon repair |
| CN111840234A (zh) * | 2020-08-14 | 2020-10-30 | 瑞普(天津)生物药业有限公司 | 一种兽用复方驱虫颗粒剂及其制备方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8327761D0 (en) * | 1983-10-17 | 1983-11-16 | Janssen Pharmaceutica Nv | Parasiticidal formulations |
| NZ248486A (en) | 1993-08-24 | 1996-07-26 | Ashmont Holdings Limited Subst | Stable anthelmintic formulation containing closantel and one or more avermectins or milbemycins in a glycol based solvent |
| DE19654079A1 (de) * | 1996-12-23 | 1998-06-25 | Bayer Ag | Endo-ekto-parasitizide Mittel |
| CA2211949A1 (en) * | 1997-07-21 | 1999-01-29 | David Farley Johnson | Nonaqueous compositions for parenteral administration |
| NZ508969A (en) | 1999-06-04 | 2002-12-20 | Nufarm Ltd | Pesticidal emulsion containing levamisole in the aqueous phase and a macrocyclic lactone anthelmintic in the organic phase |
| NZ515772A (en) | 1999-06-04 | 2002-12-20 | Nufarm Ltd | Pesticidal emulsion composition containing levamisole in the aqueous phase and an anthelmintic in the organic phase |
| LT1610613T (lt) | 2003-04-04 | 2017-03-27 | Merial, Inc. | Vietinio taikymo antihelmintinės veterinarinės kompozicijos |
| NZ535644A (en) | 2003-07-25 | 2007-05-31 | Ashmont Holdings Ltd | Anthelmintic formulations |
| KR101233488B1 (ko) | 2005-09-15 | 2013-02-14 | 메리얼 리미티드 | 구충 제형 |
| NZ552040A (en) * | 2006-12-13 | 2009-04-30 | Bomac Research Ltd | Veterinary formulation comprising an anthelmintic compound and glyceryl acetate |
| RU2367435C1 (ru) * | 2008-03-26 | 2009-09-20 | Александр Анатольевич Смирнов | Состав для лечения гельминтозов домашних животных |
| AR081970A1 (es) | 2010-06-24 | 2012-10-31 | Intervet Int Bv | Formulacion inyectable de una lactona macrociclica y levamisol, formulacion y uso veterinario |
| NZ594610A (en) * | 2011-08-16 | 2013-03-28 | Virbac New Zealand Ltd | Injectable Anthelmintic Formulations cotaining levamisole and one or more macrocyclic lactones for controlling internal parasites in ruminants |
| WO2013043064A1 (en) * | 2011-09-23 | 2013-03-28 | Alleva Animal Health Limited | Veterinary anthelmintic delivery system |
-
2014
- 2014-03-24 NZ NZ622869A patent/NZ622869A/en unknown
- 2014-03-24 NZ NZ701697A patent/NZ701697A/en unknown
-
2015
- 2015-03-24 EP EP15767761.8A patent/EP3122352A4/en active Pending
- 2015-03-24 MX MX2016012319A patent/MX389554B/es unknown
- 2015-03-24 WO PCT/NZ2015/000018 patent/WO2015147655A1/en not_active Ceased
- 2015-03-24 RU RU2016140272A patent/RU2711200C2/ru active
- 2015-03-24 CN CN201580015455.3A patent/CN106132409B/zh active Active
- 2015-03-24 UY UY0001036045A patent/UY36045A/es active IP Right Grant
- 2015-03-24 AU AU2015237371A patent/AU2015237371A1/en not_active Abandoned
- 2015-03-24 CA CA2942008A patent/CA2942008C/en active Active
- 2015-03-25 AR ARP150100871A patent/AR099829A1/es active IP Right Grant
-
2016
- 2016-09-23 US US15/274,346 patent/US10449179B2/en active Active
-
2020
- 2020-09-03 AU AU2020227063A patent/AU2020227063A1/en not_active Abandoned
-
2022
- 2022-10-11 AU AU2022252717A patent/AU2022252717B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| RU2711200C2 (ru) | 2020-01-15 |
| EP3122352A1 (en) | 2017-02-01 |
| MX389554B (es) | 2025-03-20 |
| AU2022252717A1 (en) | 2022-11-03 |
| CN106132409B (zh) | 2020-09-01 |
| EP3122352A4 (en) | 2017-11-01 |
| CA2942008C (en) | 2022-06-21 |
| AR099829A1 (es) | 2016-08-24 |
| AU2015237371A1 (en) | 2016-09-15 |
| RU2016140272A (ru) | 2018-04-24 |
| RU2016140272A3 (es) | 2018-09-26 |
| NZ701697A (en) | 2016-05-27 |
| CN106132409A (zh) | 2016-11-16 |
| US10449179B2 (en) | 2019-10-22 |
| CA2942008A1 (en) | 2015-10-01 |
| AU2022252717B2 (en) | 2024-09-05 |
| NZ622869A (en) | 2015-01-30 |
| WO2015147655A1 (en) | 2015-10-01 |
| UY36045A (es) | 2015-07-31 |
| US20170007584A1 (en) | 2017-01-12 |
| AU2020227063A1 (en) | 2020-09-24 |
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