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MX2016011745A - Variantes de hppd y metodos de uso. - Google Patents

Variantes de hppd y metodos de uso.

Info

Publication number
MX2016011745A
MX2016011745A MX2016011745A MX2016011745A MX2016011745A MX 2016011745 A MX2016011745 A MX 2016011745A MX 2016011745 A MX2016011745 A MX 2016011745A MX 2016011745 A MX2016011745 A MX 2016011745A MX 2016011745 A MX2016011745 A MX 2016011745A
Authority
MX
Mexico
Prior art keywords
hppd
inhibitors
slow
binding
enzymes
Prior art date
Application number
MX2016011745A
Other languages
English (en)
Inventor
Poree Fabien
Peters Cheryl
Armstrong Roxanne
Dubald Manuel
Original Assignee
Bayer Cropscience Lp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Cropscience Lp filed Critical Bayer Cropscience Lp
Publication of MX2016011745A publication Critical patent/MX2016011745A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8274—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for herbicide resistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0069—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y113/00—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13)
    • C12Y113/11—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13) with incorporation of two atoms of oxygen (1.13.11)
    • C12Y113/11027—4-Hydroxyphenylpyruvate dioxygenase (1.13.11.27)

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

En la presente invención, se describen enzimas de HPPD y plantas que contienen las mismas que muestran una tolerancia total frente a varias clases de inhibidores de HPPD. Se ha diseñado un conjunto de enzimas de HPPD que o bien no tienen afinidad o bien solo tienen una afinidad significativamente reducida por los inhibidores de HPPD y, al mismo tiempo, la velocidad de disociación de los inhibidores de HPPD de la enzima se aumenta en tal medida que los inhibidores de HPPD ya no actúan como inhibidores de unión lenta o unión fuerte, lenta sino que, en lugar de esto, se han convertido en inhibidores totalmente reversibles. En particular, se proporcionan polinucleótidos aislados que codifican para polipéptidos con tolerancia a inhibidores de HPPD. Adicionalmente, están englobadas secuencias de aminoácido correspondientes a los polinucleótidos.
MX2016011745A 2014-03-11 2015-03-10 Variantes de hppd y metodos de uso. MX2016011745A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461951455P 2014-03-11 2014-03-11
PCT/US2015/019610 WO2015138394A2 (en) 2014-03-11 2015-03-10 Hppd variants and methods of use

Publications (1)

Publication Number Publication Date
MX2016011745A true MX2016011745A (es) 2017-09-01

Family

ID=53433249

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016011745A MX2016011745A (es) 2014-03-11 2015-03-10 Variantes de hppd y metodos de uso.

Country Status (10)

Country Link
US (1) US10876130B2 (es)
EP (1) EP3117003B1 (es)
CN (1) CN106459986B (es)
AR (1) AR099719A1 (es)
BR (1) BR112016020889B1 (es)
CA (1) CA2942171C (es)
MX (1) MX2016011745A (es)
UY (1) UY36026A (es)
WO (1) WO2015138394A2 (es)
ZA (1) ZA201606243B (es)

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WO2018119361A1 (en) * 2016-12-22 2018-06-28 Bayer Cropscience Lp Elite event ee-gm4 and methods and kits for identifying such event in biological samples
CA3046098A1 (en) * 2016-12-22 2018-06-28 BASF Agricultural Solutions Seed US LLC Elite event ee-gm5 and methods and kits for identifying such event in biological samples
CA3055317A1 (en) * 2017-03-07 2018-09-13 BASF Agricultural Solutions Seed US LLC Hppd variants and methods of use
CN107794263B (zh) * 2017-09-30 2019-10-11 河北大学 一种提高黑色素产率的基因及其应用
WO2019083808A1 (en) 2017-10-24 2019-05-02 Basf Se IMPROVING HERBICIDE TOLERANCE AGAINST HPPD INHIBITORS BY REGULATION OF PUTATIVE REDUCED 4-HYDROXYPHENYLPYRUVATE REDUCES IN SOYBEANS
US11279944B2 (en) * 2017-10-24 2022-03-22 BASF Agricultural Solutions Seed US LLC Of herbicide tolerance to 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitors by down-regulation of HPPD expression in soybean
BR112020023836A2 (pt) * 2018-05-25 2021-04-20 BASF Agricultural Solutions Seed US LLC planta, processos para controle de ervas daninhas, para proteger as plantas, para a produção de uma planta e para aumentar o rendimento de plantas e uso da planta
AU2019275108A1 (en) * 2018-05-25 2020-12-03 BASF Agricultural Solutions Seed US LLC Plants containing elite event EE-GM4 and methods and kits for identifying such event in biological samples, and treatment thereof
JP2021525774A (ja) 2018-06-04 2021-09-27 バイエル アクチェンゲゼルシャフトＢａｙｅｒ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 除草活性二環式ベンゾイルピラゾール
WO2020221312A1 (zh) * 2019-04-30 2020-11-05 山东舜丰生物科技有限公司 抗除草剂基因、多肽及其在植物育种中的应用
CA3151807A1 (en) * 2019-09-05 2021-03-11 Plantarc Bio Ltd. Compositions and methods for controlling plant growth
CN113574173A (zh) * 2019-09-17 2021-10-29 北京大北农生物技术有限公司 突变的羟基苯丙酮酸双加氧酶多肽、其编码基因及用途
WO2023126317A1 (en) * 2021-12-28 2023-07-06 Advanta Holdings B.V. Hppd inhibitor herbicide tolerant plant
AU2023353668A1 (en) * 2022-09-27 2025-04-10 Bayer Aktiengesellschaft Herbicide/safener combination based on safeners from the class of substituted [(1,5-diphenyl-1h-1,2,4-triazol-3-yl)oxy]acetic acids and their salts

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