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MX2016010565A - Inmunoterapia del cancer a través de la combinacion de estimulacion inmunatoria local y sistemica. - Google Patents

Inmunoterapia del cancer a través de la combinacion de estimulacion inmunatoria local y sistemica.

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Publication number
MX2016010565A
MX2016010565A MX2016010565A MX2016010565A MX2016010565A MX 2016010565 A MX2016010565 A MX 2016010565A MX 2016010565 A MX2016010565 A MX 2016010565A MX 2016010565 A MX2016010565 A MX 2016010565A MX 2016010565 A MX2016010565 A MX 2016010565A
Authority
MX
Mexico
Prior art keywords
local
immune stimulation
combination
cancer immunotherapy
systemic immune
Prior art date
Application number
MX2016010565A
Other languages
English (en)
Other versions
MX375123B (es
Inventor
Henrik Ter Meulen Jan
V Payacuenca Carlos
Original Assignee
Immune Design Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immune Design Corp filed Critical Immune Design Corp
Publication of MX2016010565A publication Critical patent/MX2016010565A/es
Publication of MX375123B publication Critical patent/MX375123B/es

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Abstract

Se proporcionan en la presente composiciones y métodos para la inmunoterapia de cánceres, dichos métodos combinan la vacunación sistémica con un vector de expresión recombinante que codifica un antígeno viral y/o antígeno específico para inducir linfocitos T CD8 activados, con una estimulación inmunitaria local (por ej., intratumoral) usando aplicación estándar o modificada de un agonista de TLR para inducir la inflación local y las respuestas inmunitarias innatas que captan linfocitos T hacia el tumor.
MX2016010565A 2014-02-14 2015-02-13 Composición para usarse en mejorar la respuesta inmune contra el cáncer. MX375123B (es)

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US201462072548P 2014-10-30 2014-10-30
US201562101335P 2015-01-08 2015-01-08
PCT/US2015/015767 WO2015123496A1 (en) 2014-02-14 2015-02-13 Immunotherapy of cancer through combination of local and systemic immune stimulation

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IL247066A0 (en) 2016-09-29
BR112016018521A2 (pt) 2017-10-17
JP6581101B2 (ja) 2019-09-25
JP2017506641A (ja) 2017-03-09
CA2939093A1 (en) 2015-08-20
ES2738582T3 (es) 2020-01-23
EP3104878A1 (en) 2016-12-21
EP3104878B1 (en) 2019-05-22
JP2019203013A (ja) 2019-11-28
AU2015218365A1 (en) 2016-09-01
US20160058852A1 (en) 2016-03-03
EA035259B1 (ru) 2020-05-21
SG11201606625RA (en) 2016-09-29
IL247066B (en) 2020-11-30
MX375123B (es) 2025-03-06
WO2015123496A1 (en) 2015-08-20
EP3542816A1 (en) 2019-09-25
EA201691631A1 (ru) 2017-01-30

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