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MX2016010345A - Celulas para inmunoterapia diseñadas para dirigir antigeno presente tanto en celulas inmunes y celulas patologicas. - Google Patents

Celulas para inmunoterapia diseñadas para dirigir antigeno presente tanto en celulas inmunes y celulas patologicas.

Info

Publication number
MX2016010345A
MX2016010345A MX2016010345A MX2016010345A MX2016010345A MX 2016010345 A MX2016010345 A MX 2016010345A MX 2016010345 A MX2016010345 A MX 2016010345A MX 2016010345 A MX2016010345 A MX 2016010345A MX 2016010345 A MX2016010345 A MX 2016010345A
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MX
Mexico
Prior art keywords
cells
immunotherapy
pathological
immune
designed
Prior art date
Application number
MX2016010345A
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English (en)
Other versions
MX378913B (es
Inventor
Poirot Laurent
Duchateau Philippe
Original Assignee
Cellectis
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50114255&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2016010345(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cellectis filed Critical Cellectis
Publication of MX2016010345A publication Critical patent/MX2016010345A/es
Publication of MX378913B publication Critical patent/MX378913B/es

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    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
    • A61K40/4224—Molecules with a "CD" designation not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4231—Cytokines
    • A61K40/4232—Tumor necrosis factors [TNF] or CD70
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
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    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
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  • Public Health (AREA)
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  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Métodos de desarrollo de células inmune diseñados genéticamente para inmunoterapia, las cuales se encuentran dotadas con Receptores de Antígenos Quiméricos que dirigen un marcador de antígeno que es común tanto para las células patológicas y las células inmunes (ejemplo: CD38, CS1 o CD70) por el hecho de que los genes que dosifican los marcadores están inactivos en las células inmune por una endonucleasa de corte poco frecuente tal como TALEN, Cas9 o argonauta.
MX2016010345A 2014-02-14 2015-02-13 Células para inmunoterapia diseñadas para dirigir antígeno presente tanto en células inmunes y células patológicas. MX378913B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201470076 2014-02-14
PCT/EP2015/053162 WO2015121454A1 (en) 2014-02-14 2015-02-13 Cells for immunotherapy engineered for targeting antigen present both on immune cells and pathological cells

Publications (2)

Publication Number Publication Date
MX2016010345A true MX2016010345A (es) 2017-01-23
MX378913B MX378913B (es) 2025-03-10

Family

ID=50114255

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016010345A MX378913B (es) 2014-02-14 2015-02-13 Células para inmunoterapia diseñadas para dirigir antígeno presente tanto en células inmunes y células patológicas.

Country Status (19)

Country Link
US (3) US10836998B2 (es)
EP (2) EP3505623B1 (es)
JP (1) JP6673838B2 (es)
KR (1) KR102157924B1 (es)
CN (1) CN106029875B (es)
AU (1) AU2015216875B2 (es)
BR (1) BR112016017806B1 (es)
CA (1) CA2937711C (es)
DK (1) DK3105317T3 (es)
ES (1) ES2711498T3 (es)
HU (1) HUE041497T2 (es)
IL (1) IL246645B (es)
MX (1) MX378913B (es)
NO (1) NO20161276A1 (es)
PL (1) PL3105317T3 (es)
PT (1) PT3105317T (es)
RU (1) RU2714258C2 (es)
TR (1) TR201819571T4 (es)
WO (1) WO2015121454A1 (es)

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