MX2016006464A - Composicion farmaceutica de una combinacion de clorhidrato de tramadol-etoricoxib para el tratamiento del dolor. - Google Patents
Composicion farmaceutica de una combinacion de clorhidrato de tramadol-etoricoxib para el tratamiento del dolor.Info
- Publication number
- MX2016006464A MX2016006464A MX2016006464A MX2016006464A MX2016006464A MX 2016006464 A MX2016006464 A MX 2016006464A MX 2016006464 A MX2016006464 A MX 2016006464A MX 2016006464 A MX2016006464 A MX 2016006464A MX 2016006464 A MX2016006464 A MX 2016006464A
- Authority
- MX
- Mexico
- Prior art keywords
- etoricoxib
- tramadol
- hydrochloride
- pain
- treatment
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000008187 granular material Substances 0.000 abstract 3
- 239000011248 coating agent Substances 0.000 abstract 2
- 238000000576 coating method Methods 0.000 abstract 2
- PPKXEPBICJTCRU-XMZRARIVSA-N (R,R)-tramadol hydrochloride Chemical compound Cl.COC1=CC=CC([C@]2(O)[C@H](CCCC2)CN(C)C)=C1 PPKXEPBICJTCRU-XMZRARIVSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- MNJVRJDLRVPLFE-UHFFFAOYSA-N etoricoxib Chemical compound C1=NC(C)=CC=C1C1=NC=C(Cl)C=C1C1=CC=C(S(C)(=O)=O)C=C1 MNJVRJDLRVPLFE-UHFFFAOYSA-N 0.000 abstract 1
- 229960004945 etoricoxib Drugs 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 229960003107 tramadol hydrochloride Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4833—Encapsulating processes; Filling of capsules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención consiste en un proceso y composición farmacéutica de una combinación de clorhidrato de tramadol-etoricoxib para el tratamiento del dolor, cuyo proceso de obtención está dado a partir de dos activos la cual consiste en gránulos y/o multiparticulados con clorhidrato de tramadol y gránulos y/o multiparticulados con etoricoxib los cuales pueden estar contenidos en una mezcla de polvos, o comprimidos en una tableta bicapa con o sin recubrimiento o en una capsula como granulados y/o tabletas con o sin recubrimiento.
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2016006464A MX2016006464A (es) | 2016-05-18 | 2016-05-18 | Composicion farmaceutica de una combinacion de clorhidrato de tramadol-etoricoxib para el tratamiento del dolor. |
| EP17798843.3A EP3338771A4 (en) | 2016-05-18 | 2017-05-11 | PHARMACEUTICAL COMPOSITION COMPRISING A COMBINATION OF TRAMADOL-ETORICOXIB CHLORHYDRATE FOR THE TREATMENT OF PAIN |
| PCT/IB2017/052775 WO2017199140A1 (es) | 2016-05-18 | 2017-05-11 | Composición farmacéutica de una combinación de clorhidrato de tramadol-etoricoxib para el tratamiento del dolor |
| CA2997600A CA2997600A1 (en) | 2016-05-18 | 2017-05-11 | Pharmaceutical composition of a combination of tramadol-etoricoxib hydrochloride for the treatment of pain |
| US16/008,277 US20190060295A1 (en) | 2016-05-18 | 2017-05-11 | Pharmaceutical composition of a combination of tramadol-etoricoxib hydrochloride for the treatment of pain |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2016006464A MX2016006464A (es) | 2016-05-18 | 2016-05-18 | Composicion farmaceutica de una combinacion de clorhidrato de tramadol-etoricoxib para el tratamiento del dolor. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2016006464A true MX2016006464A (es) | 2017-11-17 |
Family
ID=60325762
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016006464A MX2016006464A (es) | 2016-05-18 | 2016-05-18 | Composicion farmaceutica de una combinacion de clorhidrato de tramadol-etoricoxib para el tratamiento del dolor. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20190060295A1 (es) |
| EP (1) | EP3338771A4 (es) |
| CA (1) | CA2997600A1 (es) |
| MX (1) | MX2016006464A (es) |
| WO (1) | WO2017199140A1 (es) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4585207A1 (en) | 2024-01-12 | 2025-07-16 | Laboratorios Silanes, S.A. de C.V. | Synergic and stable pharmaceutical composition of an nsaid and an opioid analgesic for pain and inflammation |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2017009660A (es) * | 2017-07-26 | 2017-11-23 | Laboratorios Liomont S A De C V | Composicion farmaceutica con un rango de relacion entre el clorhidrato de tramadol y el etoricoxib para su administracion para el tratamiento del dolor. |
| MX2018013070A (es) | 2017-12-29 | 2019-10-15 | Gruenenthal Gmbh | Combinación farmacéutica que comprende clorhidrato de tramadol de liberación extendida y etoricoxib de liberación inmediata, y su uso para el tratamiento del dolor. |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000051685A1 (en) * | 1999-03-01 | 2000-09-08 | Ortho-Mcneil Pharmaceutical, Inc. | Composition comprising a tramadol material and a selective cox-2 inhibitor drug |
| US20080026054A1 (en) * | 2007-04-27 | 2008-01-31 | Nectid Inc. | Novel anelgesic combination |
| EP2177215A1 (en) * | 2008-10-17 | 2010-04-21 | Laboratorios Del. Dr. Esteve, S.A. | Co-crystals of tramadol and NSAIDs |
| EP2281558A1 (en) * | 2009-08-06 | 2011-02-09 | Laboratorios Del. Dr. Esteve, S.A. | Pharmaceutical compounds of O-Desmethyl-Tramadol and COX-inhibitors |
| EP2311446A1 (en) * | 2009-10-16 | 2011-04-20 | Laboratorios Del. Dr. Esteve, S.A. | Compositions comprising Tramadol and Celecoxib in the treatment of pain |
| SG178835A1 (en) * | 2009-10-16 | 2012-05-30 | Esteve Labor Dr | Co-crystals of tramadol and coxibs |
| HUE033525T2 (en) * | 2012-08-27 | 2017-12-28 | Cadila Healthcare Ltd | Pharmaceuticals containing Etoricoxib |
-
2016
- 2016-05-18 MX MX2016006464A patent/MX2016006464A/es unknown
-
2017
- 2017-05-11 CA CA2997600A patent/CA2997600A1/en not_active Abandoned
- 2017-05-11 US US16/008,277 patent/US20190060295A1/en not_active Abandoned
- 2017-05-11 WO PCT/IB2017/052775 patent/WO2017199140A1/es not_active Ceased
- 2017-05-11 EP EP17798843.3A patent/EP3338771A4/en not_active Withdrawn
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4585207A1 (en) | 2024-01-12 | 2025-07-16 | Laboratorios Silanes, S.A. de C.V. | Synergic and stable pharmaceutical composition of an nsaid and an opioid analgesic for pain and inflammation |
Also Published As
| Publication number | Publication date |
|---|---|
| US20190060295A1 (en) | 2019-02-28 |
| EP3338771A4 (en) | 2019-05-08 |
| EP3338771A1 (en) | 2018-06-27 |
| CA2997600A1 (en) | 2017-11-23 |
| WO2017199140A1 (es) | 2017-11-23 |
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