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MX2016005718A - Metodos de uso de acil-coa sintetasa para produccion biosintetica de acil-coas. - Google Patents

Metodos de uso de acil-coa sintetasa para produccion biosintetica de acil-coas.

Info

Publication number
MX2016005718A
MX2016005718A MX2016005718A MX2016005718A MX2016005718A MX 2016005718 A MX2016005718 A MX 2016005718A MX 2016005718 A MX2016005718 A MX 2016005718A MX 2016005718 A MX2016005718 A MX 2016005718A MX 2016005718 A MX2016005718 A MX 2016005718A
Authority
MX
Mexico
Prior art keywords
acyl
coas
methods
coa synthetase
biosynthetic production
Prior art date
Application number
MX2016005718A
Other languages
English (en)
Inventor
Hui Chen
Hongxue Wang
Xiaodan Yu
Original Assignee
Conagen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Conagen Inc filed Critical Conagen Inc
Publication of MX2016005718A publication Critical patent/MX2016005718A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y602/00—Ligases forming carbon-sulfur bonds (6.2)
    • C12Y602/01—Acid-Thiol Ligases (6.2.1)
    • C12Y602/01001—Acetate-CoA ligase (6.2.1.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Nutrition Science (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Oil, Petroleum & Natural Gas (AREA)

Abstract

Se describe un método biosintético para hacer carboxil CoA a partir de ácido carboxílico de cadena larga que incluye expresar una ACS en un sistema celular, alimentar un ácido carboxílico de cadena larga al sistema celular, hacer crecer el sistema celular en un medio, y producir carboxil CoA.
MX2016005718A 2013-11-01 2014-11-03 Metodos de uso de acil-coa sintetasa para produccion biosintetica de acil-coas. MX2016005718A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361898944P 2013-11-01 2013-11-01
PCT/US2014/063695 WO2015066615A2 (en) 2013-11-01 2014-11-03 Methods of using acyl-coa synthetase for biosynthetic production of acyl-coas

Publications (1)

Publication Number Publication Date
MX2016005718A true MX2016005718A (es) 2016-12-08

Family

ID=53005405

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016005718A MX2016005718A (es) 2013-11-01 2014-11-03 Metodos de uso de acil-coa sintetasa para produccion biosintetica de acil-coas.

Country Status (9)

Country Link
US (1) US10392643B2 (es)
EP (1) EP3063283A4 (es)
JP (1) JP6587358B2 (es)
KR (1) KR20160126969A (es)
CN (1) CN105916991A (es)
BR (1) BR112016009764A2 (es)
CA (1) CA2962266A1 (es)
MX (1) MX2016005718A (es)
WO (1) WO2015066615A2 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20180101445A (ko) 2016-01-07 2018-09-12 코나겐 인크. 생합성 프로세스에 의해 캡시노이드를 제조하는 방법
US11459591B2 (en) 2016-07-19 2022-10-04 Conagen Inc. Method for the microbial production of specific natural capsaicinoids
CN107083412B (zh) * 2017-06-13 2021-05-28 刘超 一种中短链酰基辅酶a合成酶的应用
IL305756A (en) * 2021-03-10 2023-11-01 Yeda Res & Dev An acyl-activating enzyme, and a cell, tissue, and organism that contain it are tensogens.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5958745A (en) * 1996-03-13 1999-09-28 Monsanto Company Methods of optimizing substrate pools and biosynthesis of poly-β-hydroxybutyrate-co-poly-β-hydroxyvalerate in bacteria and plants
US20070244192A1 (en) 1999-01-14 2007-10-18 Martek Biosciences Corporation Plant seed oils containing polyunsaturated fatty acids
US20040010817A1 (en) 2000-07-21 2004-01-15 Washington State University Research Foundation Plant acyl-CoA synthetases
GB0421937D0 (en) 2004-10-02 2004-11-03 Univ York Acyl CoA synthetases
US20070220634A1 (en) 2006-03-15 2007-09-20 Martek Biosciences Corporation Plant seed oils containing polyunsaturated fatty acids
CN103087998B (zh) 2012-10-30 2014-09-03 浙江工业大学 冬虫夏草合成十六烷基-辅酶a的酶、基因及其应用
CN103725652B (zh) 2013-12-25 2016-06-29 无锡新和源发酵技术研究院有限公司 一种酰基辅酶a合成酶及其应用

Also Published As

Publication number Publication date
JP2016534758A (ja) 2016-11-10
WO2015066615A2 (en) 2015-05-07
WO2015066615A3 (en) 2015-06-25
US20160273014A1 (en) 2016-09-22
US20170247733A2 (en) 2017-08-31
KR20160126969A (ko) 2016-11-02
CA2962266A1 (en) 2015-05-07
BR112016009764A2 (pt) 2017-12-05
EP3063283A2 (en) 2016-09-07
JP6587358B2 (ja) 2019-10-09
EP3063283A4 (en) 2017-07-05
US10392643B2 (en) 2019-08-27
CN105916991A (zh) 2016-08-31

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