MX2016003791A - Composiciones y método para desestabilizar, alterar y dispersar biopelículas. - Google Patents
Composiciones y método para desestabilizar, alterar y dispersar biopelículas.Info
- Publication number
- MX2016003791A MX2016003791A MX2016003791A MX2016003791A MX2016003791A MX 2016003791 A MX2016003791 A MX 2016003791A MX 2016003791 A MX2016003791 A MX 2016003791A MX 2016003791 A MX2016003791 A MX 2016003791A MX 2016003791 A MX2016003791 A MX 2016003791A
- Authority
- MX
- Mexico
- Prior art keywords
- biofilms
- altering
- compositions
- destabilizing
- removal
- Prior art date
Links
- 230000000368 destabilizing effect Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000007613 environmental effect Effects 0.000 abstract 2
- 238000011282 treatment Methods 0.000 abstract 2
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 abstract 1
- 229930064664 L-arginine Natural products 0.000 abstract 1
- 235000014852 L-arginine Nutrition 0.000 abstract 1
- 206010070834 Sensitisation Diseases 0.000 abstract 1
- 239000004599 antimicrobial Substances 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 230000035945 sensitivity Effects 0.000 abstract 1
- 230000008313 sensitization Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4425—Pyridinium derivatives, e.g. pralidoxime, pyridostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
- C12Q1/14—Streptococcus; Staphylococcus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6806—Determination of free amino acids
- G01N33/6812—Assays for specific amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Birds (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Toxicology (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
Abstract
La presente descripción se relaciona con composiciones y métodos para desestabilizar biopelículas, alterar la estructura 3D de biopelículas y dispersar biopelículas, para mejorar la remoción de células de la biopelícula y/o sensibilidad a otros agentes (por ejemplo, tratamientos ambientales y aplicados concurrentemente) En particular, la presente descripción se relaciona con el uso de L-arginina en la remoción y/o sensibilización (por ejemplo, a antimicrobianos) de microorganismos en aplicaciones médicas, industriales, domésticas o ambientales, así como el tratamiento de infecciones bacterianas (por ejemplo, en biopelículas).
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361881762P | 2013-09-24 | 2013-09-24 | |
| US201461972920P | 2014-03-31 | 2014-03-31 | |
| PCT/US2014/057235 WO2015048146A1 (en) | 2013-09-24 | 2014-09-24 | Compositions and method for destabilizing, altering, and dispersing biofilms |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2016003791A true MX2016003791A (es) | 2017-01-20 |
| MX374836B MX374836B (es) | 2025-03-06 |
Family
ID=52744423
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016003791A MX374836B (es) | 2013-09-24 | 2014-09-24 | Plásmido para monitorizar arginina o ai-2 en biopelículas. |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20160235698A1 (es) |
| EP (3) | EP3049073B1 (es) |
| CN (3) | CN115177607A (es) |
| AU (6) | AU2014326756B2 (es) |
| BR (1) | BR112016006584B1 (es) |
| DK (1) | DK3049073T3 (es) |
| ES (1) | ES2847388T3 (es) |
| MX (1) | MX374836B (es) |
| PL (1) | PL3049073T3 (es) |
| WO (1) | WO2015048146A1 (es) |
| ZA (1) | ZA201602797B (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5548121B2 (ja) | 2007-05-14 | 2014-07-16 | リサーチ ファウンデーション オブ ステイト ユニバーシティ オブ ニューヨーク | バイオフィルム中の細菌細胞における生理学的分散応答の誘導 |
| WO2015048146A1 (en) | 2013-09-24 | 2015-04-02 | The Regents Of The University Of Michigan | Compositions and method for destabilizing, altering, and dispersing biofilms |
| US9795579B1 (en) * | 2017-04-24 | 2017-10-24 | Knoze Jr. Corporation | Oral microbiota promoting method |
| US12194105B2 (en) * | 2018-02-21 | 2025-01-14 | The Board Of Trustees Of The Leland Stanford Junior University | Composition and method for new antimicrobial agents with secondary mode of action provided by conjugation of an antimicrobial to a guanidinium-rich molecular transporter |
| US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
| US10927397B2 (en) | 2018-10-16 | 2021-02-23 | Sterilex, Llc | Compositions, devices and methods for detecting biofilms |
| CA3123091A1 (en) * | 2018-12-26 | 2020-07-02 | Colgate-Palmolive Company | Methods of shifting biofilm in the oral cavity from pathogenic to healthy biofilm |
| CN113271918A (zh) * | 2018-12-26 | 2021-08-17 | 高露洁-棕榄公司 | 使用精氨酸降低病原性细菌 |
| US20210196598A1 (en) * | 2018-12-26 | 2021-07-01 | Colgate-Palmolive Company | Specific Co-Aggregation Inhibition by Arginine |
| AU2020253232B2 (en) * | 2019-03-29 | 2022-12-08 | Colgate-Palmolive Company | Oral care product |
| CN110583697B (zh) * | 2019-09-20 | 2021-04-06 | 浙江工商大学 | 去除铜绿假单胞菌生物膜用的高效化学生物制剂及其应用 |
| US12332160B2 (en) | 2019-11-08 | 2025-06-17 | Colgate-Palmolive Company | Apparatus, system, and method for testing biological samples |
| WO2021092613A1 (en) * | 2019-11-08 | 2021-05-14 | Colgate-Palmolive Company | Methods of modifying biofilm |
| CN111299267B (zh) * | 2020-02-12 | 2021-10-22 | 上海交通大学 | 一种基于群感效应的供水管网生物膜控制方法及其应用 |
| WO2023114550A2 (en) * | 2021-12-19 | 2023-06-22 | The Trustees Of Columbia University In The City Of New York | Engineering bacteria swarm patterns for spatiotemporal information encoding |
| CN119112857A (zh) * | 2024-09-18 | 2024-12-13 | 中国科学技术大学 | 抑制金葡菌生物被膜形成的组合物及其应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4539234A (en) | 1981-05-27 | 1985-09-03 | Unitika Ltd. | Urethral catheter capable of preventing urinary tract infection and process for producing the same |
| EP1159951A1 (en) * | 2000-06-02 | 2001-12-05 | Societe Des Produits Nestle S.A. | Use of exogenous lactic bacteria strain against Actinomyces naeslundii-related diseases |
| WO2000066616A1 (en) * | 1999-05-03 | 2000-11-09 | Advanced Research & Technology Institute, Inc. | METHODS AND COMPOSITIONS FOR CONTROLLING DENTAL CARIES, AND RECOMBINANT SmaA POLYPEPTIDES USEFUL FOR SAME |
| AU2001286741A1 (en) * | 2000-08-25 | 2002-03-04 | Trustees Of Tufts College | Methods and compositions for potentiating antibiotic action against persistent/tolerant pathogenic microorganisms |
| US20100021942A1 (en) * | 2008-07-25 | 2010-01-28 | Paul Freemont | Cell-free expression system for the detection of bacterial biofilms |
| ES2385236B8 (es) * | 2008-12-22 | 2014-01-31 | Micropure Inc. | Composición y método para reducir la desmineralización de los dientes. |
| BR112012030037B1 (pt) * | 2010-06-23 | 2017-06-27 | Colgate-Palmolive Company | Oral hygiene composition, use and article |
| CA2816241C (en) | 2010-10-27 | 2016-04-19 | Colgate-Palmolive Company | Oral care composition comprising arginine and calcium carbonate |
| US9717929B2 (en) * | 2010-12-07 | 2017-08-01 | Colgate-Palmolive Company | Dentifrice compositions containing calcium silicate and a basic amino acid |
| CA2853857C (en) * | 2011-10-31 | 2022-06-14 | Kane Biotech Inc. | Compositions and methods for preventing and treating oral diseases |
| RU2014128847A (ru) * | 2011-12-15 | 2016-02-10 | Колгейт-Палмолив Компани | Композиции для гигиены полости рта |
| WO2015048146A1 (en) | 2013-09-24 | 2015-04-02 | The Regents Of The University Of Michigan | Compositions and method for destabilizing, altering, and dispersing biofilms |
-
2014
- 2014-09-24 WO PCT/US2014/057235 patent/WO2015048146A1/en not_active Ceased
- 2014-09-24 EP EP14847319.2A patent/EP3049073B1/en not_active Revoked
- 2014-09-24 CN CN202210703882.2A patent/CN115177607A/zh active Pending
- 2014-09-24 MX MX2016003791A patent/MX374836B/es active IP Right Grant
- 2014-09-24 CN CN201480064187.XA patent/CN106029062A/zh active Pending
- 2014-09-24 EP EP16195796.4A patent/EP3150715B1/en active Active
- 2014-09-24 AU AU2014326756A patent/AU2014326756B2/en active Active
- 2014-09-24 US US15/023,111 patent/US20160235698A1/en not_active Abandoned
- 2014-09-24 PL PL14847319T patent/PL3049073T3/pl unknown
- 2014-09-24 BR BR112016006584-0A patent/BR112016006584B1/pt active IP Right Grant
- 2014-09-24 EP EP20205086.0A patent/EP3831374A1/en active Pending
- 2014-09-24 CN CN201811621240.8A patent/CN110129352A/zh active Pending
- 2014-09-24 DK DK14847319.2T patent/DK3049073T3/da active
- 2014-09-24 ES ES14847319T patent/ES2847388T3/es active Active
-
2016
- 2016-03-31 AU AU2016202002A patent/AU2016202002B2/en active Active
- 2016-04-20 US US15/134,007 patent/US10570401B2/en active Active
- 2016-04-22 ZA ZA2016/02797A patent/ZA201602797B/en unknown
-
2019
- 2019-11-26 AU AU2019271937A patent/AU2019271937B2/en active Active
-
2021
- 2021-04-28 AU AU2021202650A patent/AU2021202650B2/en active Active
-
2022
- 2022-11-14 AU AU2022271381A patent/AU2022271381B2/en active Active
-
2024
- 2024-11-15 AU AU2024264692A patent/AU2024264692A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DK3049073T3 (da) | 2021-02-01 |
| BR112016006584B1 (pt) | 2022-11-29 |
| AU2024264692A1 (en) | 2024-12-05 |
| AU2016202002A1 (en) | 2016-04-21 |
| EP3049073A1 (en) | 2016-08-03 |
| AU2021202650B2 (en) | 2022-09-08 |
| US10570401B2 (en) | 2020-02-25 |
| MX374836B (es) | 2025-03-06 |
| AU2019271937A1 (en) | 2019-12-19 |
| EP3049073A4 (en) | 2017-03-15 |
| EP3150715A1 (en) | 2017-04-05 |
| AU2014326756A1 (en) | 2016-04-07 |
| US20160235698A1 (en) | 2016-08-18 |
| BR112016006584A2 (pt) | 2017-08-01 |
| AU2019271937B2 (en) | 2021-01-28 |
| US20160304886A1 (en) | 2016-10-20 |
| AU2021202650A1 (en) | 2021-05-27 |
| AU2014326756B2 (en) | 2019-08-29 |
| EP3831374A1 (en) | 2021-06-09 |
| CN106029062A (zh) | 2016-10-12 |
| EP3049073B1 (en) | 2020-11-04 |
| AU2022271381B2 (en) | 2024-08-15 |
| CN115177607A (zh) | 2022-10-14 |
| CN110129352A (zh) | 2019-08-16 |
| ZA201602797B (en) | 2018-12-19 |
| WO2015048146A1 (en) | 2015-04-02 |
| AU2022271381A1 (en) | 2022-12-15 |
| EP3150715B1 (en) | 2018-11-14 |
| ES2847388T3 (es) | 2021-08-03 |
| AU2016202002B2 (en) | 2017-10-12 |
| PL3049073T3 (pl) | 2021-10-25 |
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Legal Events
| Date | Code | Title | Description |
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| FG | Grant or registration |