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MX2016000057A - Derivados organometalicos de 2-ciano-2-aminobenzoato-propilo y su uso como antihelminticos. - Google Patents

Derivados organometalicos de 2-ciano-2-aminobenzoato-propilo y su uso como antihelminticos.

Info

Publication number
MX2016000057A
MX2016000057A MX2016000057A MX2016000057A MX2016000057A MX 2016000057 A MX2016000057 A MX 2016000057A MX 2016000057 A MX2016000057 A MX 2016000057A MX 2016000057 A MX2016000057 A MX 2016000057A MX 2016000057 A MX2016000057 A MX 2016000057A
Authority
MX
Mexico
Prior art keywords
organometallic
anthelmintics
aminobenzoate
derivates
cyano
Prior art date
Application number
MX2016000057A
Other languages
English (en)
Inventor
Gasser Gilles
B Gasser Robin
Jabbar Abdul
HESS Jeannine
PATRA Malay
Original Assignee
Univ Zuerich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Zuerich filed Critical Univ Zuerich
Publication of MX2016000057A publication Critical patent/MX2016000057A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/02—Iron compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N55/00—Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur
    • A01N55/02—Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur containing metal atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0046—Ruthenium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/06—Cobalt compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F17/00—Metallocenes
    • C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic Table

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La invención se refiere a compuestos caracterizados por una fórmula general (1), en la que X es un grupo descrito por una fórmula general -Kp-F1Kq-, en la que - F1 es -C(=O)-,-C(=S)-, siendo 1 0 o 1, - Kp es un alquilo Cp siendo p 0, 1, 2, 3 0 4, - Kq es un alquilo Cq siendo q 0, 1, 2, 3 o 4 y en la que n de R1n es 0, 1, 2, 3, 4 o 5 y cada R1 independientemente de cualquier otro R1- es -C(=O)OR2, - 1, R1 e22, -C(=O)SR2, -C(=S)OR2, -C(NH)NR22, CN4H2, -NR22, - C(=O)R2, -C(=S)R2, -OR2, -SR2, -CF3, -OCF3, -SCF3, -SOCF3, - SO2CF3, -CN, -NO2, -F, -C1, -Br o -I, siendo cada R2 independientemente de cualquier otro R2 hidrógeno o alquilo C1-C4 y en la que OM es un compuesto organometálico seleccionado independientemente del grupo de un compuesto sándwich metálico no sustituido o sustituido, un compuesto sándwich semimetálico no sustituido o sustituido o un compuesto carbonilo metálico y su uso en un método para el tratamiento de infecciones por helmintos.
MX2016000057A 2013-07-01 2014-07-01 Derivados organometalicos de 2-ciano-2-aminobenzoato-propilo y su uso como antihelminticos. MX2016000057A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13174551.5A EP2821412A1 (en) 2013-07-01 2013-07-01 Organometallic 2-cyano-2-aminobenzoate-propyl derivates and their use as anthelmintics
PCT/EP2014/064005 WO2015000928A1 (en) 2013-07-01 2014-07-01 Organometallic 2-cyano-2-aminobenzoate-propyl derivates and their use as anthelmintics

Publications (1)

Publication Number Publication Date
MX2016000057A true MX2016000057A (es) 2016-08-18

Family

ID=48698964

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016000057A MX2016000057A (es) 2013-07-01 2014-07-01 Derivados organometalicos de 2-ciano-2-aminobenzoato-propilo y su uso como antihelminticos.

Country Status (9)

Country Link
US (1) US9663545B2 (es)
EP (2) EP2821412A1 (es)
JP (1) JP2016523280A (es)
CN (1) CN105492452A (es)
AU (1) AU2014286220A1 (es)
CA (1) CA2916804A1 (es)
MX (1) MX2016000057A (es)
WO (1) WO2015000928A1 (es)
ZA (1) ZA201600037B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2016000055A (es) * 2013-07-01 2016-08-18 Univ Zuerich Derivados de n-(1-ciano-2-hidroxi-1-metil-etil)-4-(trifluorometils ulfanil)benzamida para su uso como farmacos nematicidas.

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6239077B1 (en) * 1998-05-01 2001-05-29 Nihon Nohyaku Co., Ltd. Aminoacetonitrile derivative agricultural and horticultural insecticide containing the same and use thereof
US7700656B2 (en) * 2000-12-20 2010-04-20 Novartis Ag Organic compounds
GB0402677D0 (en) * 2003-11-06 2004-03-10 Novartis Ag Organic compounds
WO2008062005A1 (en) * 2006-11-24 2008-05-29 Novartis Ag The use of aminoacetonitril compounds in the control of endoparasites in warm- blood animals.
MX2010002868A (es) * 2010-03-16 2011-09-21 Norma Del Carmen Galindo Sevilla N6-(ferrocenmetil)quinazolin-2,4,6-triamina (h2), sus derivados y profarmacos, como agentes antimicrobianos antiparasitarios, antiprotozoarios y antileishmanias.
UY33282A (es) * 2010-03-25 2011-09-30 Novartis Ag Composiciones endoparasiticidas
FR2961209B1 (fr) * 2010-06-11 2013-03-01 Sanofi Aventis Procede de synthese de la ferroquine par amination reductrice convergente.
WO2012013725A1 (en) * 2010-07-28 2012-02-02 Medizinische Universität Wien Vinylogous chalcone derivatives and their medical use

Also Published As

Publication number Publication date
WO2015000928A1 (en) 2015-01-08
CN105492452A (zh) 2016-04-13
AU2014286220A1 (en) 2016-01-28
JP2016523280A (ja) 2016-08-08
ZA201600037B (en) 2017-02-22
US20160368939A1 (en) 2016-12-22
CA2916804A1 (en) 2015-01-08
EP3016962B1 (en) 2018-02-28
US9663545B2 (en) 2017-05-30
EP2821412A1 (en) 2015-01-07
EP3016962A1 (en) 2016-05-11

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