MX2015011833A - Kits y métodos para el tratamiento de cáncer con péptidos de gliadina. - Google Patents
Kits y métodos para el tratamiento de cáncer con péptidos de gliadina.Info
- Publication number
- MX2015011833A MX2015011833A MX2015011833A MX2015011833A MX2015011833A MX 2015011833 A MX2015011833 A MX 2015011833A MX 2015011833 A MX2015011833 A MX 2015011833A MX 2015011833 A MX2015011833 A MX 2015011833A MX 2015011833 A MX2015011833 A MX 2015011833A
- Authority
- MX
- Mexico
- Prior art keywords
- cancer
- patient
- tyrosine kinase
- administering
- kinase inhibitor
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 6
- 108010061711 Gliadin Proteins 0.000 title abstract 5
- 206010028980 Neoplasm Diseases 0.000 title abstract 5
- 201000011510 cancer Diseases 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 229940124617 receptor tyrosine kinase inhibitor Drugs 0.000 abstract 4
- 239000002246 antineoplastic agent Substances 0.000 abstract 2
- 229940127089 cytotoxic agent Drugs 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 238000011260 co-administration Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/168—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medical Informatics (AREA)
- Inorganic Chemistry (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Optics & Photonics (AREA)
- High Energy & Nuclear Physics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Biophysics (AREA)
Abstract
En el presente documento se divulgan los equipos y los métodos para tratar el cáncer que comprenden la administración de un péptido de gliadina a un paciente. Un equipo de acuerdo con la invención comprende una composición farmacéutica que comprende un péptido de gliadina y las instrucciones para administrar el péptido a un paciente. El equipo puede además incluir una composición farmacéutica que comprende por lo menos un agente quimioterapéutico como un inhibidor del receptor tirosina cinasa y las instrucciones para coadministrar los compuestos. Un método para tratar el cáncer de acuerdo con la invención comprende administrar un péptido de gliadina a un paciente y puede además comprender coadministrar al menos un agente quimioterapéutico como un inhibidor del receptor tirosina cinasa. La coadministración de un péptido de gliadina y del inhibidor del receptor tirosina cinasa a un paciente con cáncer es eficaz para disminuir o prevenir la resistencia del cáncer al ínhibidor del receptor tirosina cinasa.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361774285P | 2013-03-07 | 2013-03-07 | |
| PCT/US2014/021660 WO2014138556A1 (en) | 2013-03-07 | 2014-03-07 | Kits and methods for the treatment of cancer using gliadin peptides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015011833A true MX2015011833A (es) | 2016-06-02 |
| MX370858B MX370858B (es) | 2020-01-08 |
Family
ID=50483486
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015011833A MX370858B (es) | 2013-03-07 | 2014-03-07 | Composiciones que comprenden péptidos de gliadina para usarse en el tratamiento de cáncer. |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US9254308B2 (es) |
| EP (1) | EP2964242B1 (es) |
| JP (1) | JP6352952B2 (es) |
| KR (1) | KR102230514B1 (es) |
| CN (2) | CN105120881A (es) |
| AU (1) | AU2014225496B2 (es) |
| BR (1) | BR112015021448B1 (es) |
| CA (1) | CA2903471C (es) |
| DK (1) | DK2964242T3 (es) |
| HK (1) | HK1212920A1 (es) |
| IL (1) | IL241230B (es) |
| MX (1) | MX370858B (es) |
| SG (1) | SG11201506963UA (es) |
| WO (1) | WO2014138556A1 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107312810B (zh) * | 2017-07-11 | 2020-10-09 | 南开大学 | 酶催化苯丁酸氮芥-多肽水凝胶的制备及抗癌应用 |
| WO2021138391A1 (en) | 2019-12-30 | 2021-07-08 | Tyra Biosciences, Inc. | Indazole compounds |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2729296B1 (fr) * | 1995-01-12 | 1997-03-28 | Europlanaire | Compositions pharmaceutiques comprenant une superoxyde dismutase |
| US20030171318A1 (en) | 2001-08-20 | 2003-09-11 | Myriad Genetics, Incorporated | Composition and method for treating viral infection |
| JP2004099459A (ja) * | 2002-09-05 | 2004-04-02 | Asama Chemical Co Ltd | 抗腫瘍剤 |
| WO2005021757A1 (en) | 2003-09-01 | 2005-03-10 | Galapagos Genomics N.V. | Polypeptides and polynucleotides for use as a medicament |
| US8957032B2 (en) * | 2008-05-06 | 2015-02-17 | Alba Therapeutics Corporation | Inhibition of gliadin peptides |
| RU2013114360A (ru) * | 2010-08-31 | 2014-10-10 | Дженентек, Инк. | Биомаркеры и способы лечения |
| WO2014002108A1 (en) * | 2012-06-27 | 2014-01-03 | Amrita Vishwa Vidyapeetham University | A core-shell nanostructure on the basis of proteins with corresponding therapeutic agents |
-
2014
- 2014-03-07 BR BR112015021448-7A patent/BR112015021448B1/pt active IP Right Grant
- 2014-03-07 US US14/200,585 patent/US9254308B2/en active Active
- 2014-03-07 JP JP2015561703A patent/JP6352952B2/ja active Active
- 2014-03-07 WO PCT/US2014/021660 patent/WO2014138556A1/en not_active Ceased
- 2014-03-07 AU AU2014225496A patent/AU2014225496B2/en active Active
- 2014-03-07 CN CN201480012163.XA patent/CN105120881A/zh active Pending
- 2014-03-07 MX MX2015011833A patent/MX370858B/es active IP Right Grant
- 2014-03-07 SG SG11201506963UA patent/SG11201506963UA/en unknown
- 2014-03-07 CN CN202410373681.XA patent/CN118217382A/zh active Pending
- 2014-03-07 HK HK16100994.8A patent/HK1212920A1/zh unknown
- 2014-03-07 EP EP14717253.0A patent/EP2964242B1/en active Active
- 2014-03-07 CA CA2903471A patent/CA2903471C/en active Active
- 2014-03-07 DK DK14717253.0T patent/DK2964242T3/en active
- 2014-03-07 KR KR1020157027813A patent/KR102230514B1/ko active Active
-
2015
- 2015-09-06 IL IL241230A patent/IL241230B/en active IP Right Grant
-
2016
- 2016-01-26 US US15/007,157 patent/US9669068B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| DK2964242T3 (en) | 2019-03-04 |
| US9254308B2 (en) | 2016-02-09 |
| NZ711682A (en) | 2021-07-30 |
| KR20150138230A (ko) | 2015-12-09 |
| US20160143991A1 (en) | 2016-05-26 |
| US9669068B2 (en) | 2017-06-06 |
| CA2903471A1 (en) | 2014-09-12 |
| JP2016529202A (ja) | 2016-09-23 |
| BR112015021448A2 (pt) | 2017-10-10 |
| CA2903471C (en) | 2022-11-01 |
| MX370858B (es) | 2020-01-08 |
| AU2014225496B2 (en) | 2018-03-15 |
| AU2014225496A1 (en) | 2015-09-24 |
| EP2964242A1 (en) | 2016-01-13 |
| IL241230B (en) | 2021-02-28 |
| CN105120881A (zh) | 2015-12-02 |
| JP6352952B2 (ja) | 2018-07-04 |
| WO2014138556A1 (en) | 2014-09-12 |
| US20140256647A1 (en) | 2014-09-11 |
| SG11201506963UA (en) | 2015-10-29 |
| HK1212920A1 (zh) | 2016-06-24 |
| KR102230514B1 (ko) | 2021-03-19 |
| IL241230A0 (en) | 2015-11-30 |
| CN118217382A (zh) | 2024-06-21 |
| BR112015021448B1 (pt) | 2022-04-19 |
| EP2964242B1 (en) | 2018-11-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |